The Fear of COVID-19: Effects on Psychosocial Factors and Quality of Life in Patients with Cystic Fibrosis

Abstract

Objective: Psychosocial effects have been reported in patients with cystic fibrosis (pwCFs), which is chronic disease, and inconsistent results were observed in pandemic between studies. This study investigated the effects of Coronavirus (COVID-19) pandemic on anxiety, depression and quality of life (QoL) levels among pwCFs. Material and Methods: The data of all participants included in the study were collected through two web-based questionnaires, one for pwCFs and general population (GP) controls. Two questionnaire versions had similar questions, prepared by the researchers. The pwCFs questionnaire augmented with CF targeted questions. Also, both questionnaires included COVID-19 Fear Scale, Hospital Anxiety Depression Scale (HADS) and World Health Organization QoL Scale Short Form (WHOQOL-Bref) question items. Results: Sixty-four pwCFs and seventy GP controls completed the questionnairesCompared to GP controls, pwCFs had increased fear of COVID-19, anxiety, depression, and decreased QoL levels (p<0.001). The fear of COVID-19 had significant effects on anxiety (R2=0.506; p<0.001), depression (R2=0.337; p<0.001), and QoL domains of general health status (R2=0.095; p=0.013), physical (R2=0.239; p<0.001) and psychological health (R2=0.275; p<0.001), and environment (R2=0.179; p<0.001), but not on social relationships (p>0.05) in pwCFs. In GP controls, the fear of COVID-19 had significant effects on anxiety and depression (p<0.05), but not on any QoL domains (p>0.05). Conclusion: According to our study findings, theincrease in fear of COVID-19 had a negative impact on anxiety, depression and QoL in pwCFs.Psychosocial influences in pwCFs need to be further investigated in future cross-sectional studies in case of a possible pandemic and lockdown.

Keywords

• Anxiety
• COVID-19
• Depression
• Cystic fibrosis
• Quality of Life

COVID-19 Korkusu: Kistik Fibrozisli Hastalarda Psikososyal Faktörler ve Yaşam Kalitesi Üzerine Etkileri

Abstract

Amaç: Kronik bir hastalık olan Kistik Fibrozis (KF) tanılı bireylerde pandemi sürecinde psikososyal etkiler ortaya konmuş ve tutarsız sonuçlar gözlenmiştir. Bu çalışma, KF'li bireylerde Koronavirüs (COVID-19) pandemisinin anksiyete, depresyon ve yaşam kalitesi (YK) seviyeleri üzerindeki etkilerini araştırdı. Gereç ve Yöntemler: Çalışmaya dahil edilen tüm katılımcıların verileri, biri KF'li bireyler ve diğeri genel popülasyon (GP) kontrolleri için olmak üzere iki internet tabanlı anket aracılığıyla toplanmıştır. İki anket versiyonunda da araştırmacılar tarafından hazırlanan benzer sorular vardı. KF'li bireyler için olan anket, KF hedefli sorularla zenginleştirildi. Ayrıca her iki ankette de COVID-19 Korkusu Ölçeği, Hastane Anksiyete Depresyon Ölçeği (HADÖ) ve Dünya Sağlık Örgütü YK Ölçeği Kısa Formu (DSÖYK-KF) soru maddeleri yer aldı. Bulgular: KF'li 64 birey ve 70 GP kontrolü anketleri tamamladı. KF'li bireyler, GP kontrollerine göre COVID-19 korkusu, anksiyete, depresyon ve düşük YK seviyelerine sahipti (p<0,001). KF'li bireylerde COVID-19 korkusunun anksiyete (R2=0,506; p<0,001), depresyon (R2=0,337; p<0,001) ve YK'nin genel sağlık durumu (R2=0,095; p=0,013), fiziksel (R2=0,239; p<0,001), psikolojik (R2=0,275; p<0,001) ve çevresel (R2=0,179; p<0,001) sağlık YK alanları üzerinde önemli etkileri olduğu, ancak sosyal ilişkiler üzerinde (p>0,05) anlamlı etkisi olmadığı görüldü. GP kontrollerinde, COVID-19 korkusunun anksiyete ve depresyon üzerinde anlamlı etkileri vardı (p<0,05), ancak herhangi bir YK alanı üzerinde yoktu (p>0,05). Sonuç: Çalışmadaki bulgularımıza göre, COVID-19 korkusundaki artışın KF’li bireylerde anksiyete, depresyon ve YK üzerinde olumsuz etkisi vardı. KF'li bireylerdeki psikososyal etkilenimler gelecekteki kesitsel çalışmalarla, olası bir pandemi ve karantina durumunda daha iyi takip edilebileceğini ve önlemlerin alınabileceğini düşünmekteyiz.

Keywords

• Anksiyete
• COVID-19
• Depresyon
• Kistik Fibrozis
• Yaşam Kalitesi

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