Şanlıurfa Bölgesinde Koyunlarda Coxiella burnetii Antikorlarının Tespiti

Abstract

Q Humması, farklı hayvan türlerini ve insanları etkileyen Coxiella burnetii'nin (C. burnetii) neden olduğu yaygın bir zoonozdur. En önemli hayvan rezervuarları sığır, koyun ve keçilerdir. Bu çalışmanın amacı, ticari bir ELISA kiti kullanarak, Türkiye'nin Şanlıurfa bölgesindeki koyunlarda C. burnetii’nin antikor varlığını belirlemektir. Şanlıurfa'nın farklı bölgelerinden daha önce laboratuvarımıza gönderilen ve abort öyküsü bulunmayan farklı yaşlarda olan 120 koyundan alınan serumlar analiz edildi. C. burnetii'nin serolojik tanısı için yapılan ELISA sonuçlarına göre 20 serumda (%16,7) pozitiflik saptandı. Pozitif 20 serumdan sekizinin çok yüksek antikor titresine sahip olduğu tespit edildi. Bu çalışmada C. burnetii’nin antikor varlığı tespit edilmiş olup, bu durumun ise bölgede bulunan hayvanların daha önce enfeksiyona maruz kalındığını düşündürmüştür. Hastalığın zoonotik doğası gereği bölgede Q humması hastalığı riski göz önünde bulundurulmalıdır. Sonuç olarak, ülkenin Güneydoğu bölgesindeki farklı tür ve yaş gruplarında olan ruminantlar için Q humması teşhisi ve yönetim prosedürleri üzerine daha fazla çalışma yapılması tavsiye edilmektedir.

Keywords

• Antikor,
• Coxiella burnetii,
• ELISA,
• Koyun,
• Q Humması

Investigation of Coxiella burnetii Antibodies in Sheep in Şanlıurfa Region

Abstract

Q fever is a common zoonosis caused by Coxiella burnetii (C. burnetii) and can affect various animal species and humans. The most important animal reservoirs are cattle, goat and sheep. The aim of this study was to determine the presence of C. burnetii in sheep in Şanlıurfa, Türkiye, using a commercial ELISA kit. The sera from 120 sheep of different ages from different regions of Şanlıurfa, were tested. These sera previously sent to our laboratory were not from the animals with a history of abortion. ELISA results for serologic diagnosis of C. burnetii showed that 20 sera (16.7%) were positive for the test. Eight of 20 positive sera were found to have very high antibody titer. In this study, antibodies against C. burnetii were detected, indicating that the animals had previously been exposed to an infection in the region. The risk of Q fever disease in the region should be taken into consideration because of the zoonotic nature of the disease. In conclusion, further studies on Q fever diagnosis and management procedures are highly recommended for different species and age groups of ruminants in Southeast part of the country.

Keywords

• Antibodies,
• Coxiella burnetii,
• ELISA,
• Sheep,
• Q Fever

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