Rus Toy Terrier Irkı Bir Köpekte Oral Fibrosarkom ve Cerrahi Sağaltımı

Abstract

Bu olgu sunumu, Rus Toy Terrier ırkı bir köpekte görülen oral fibrosarkomun cerrahi tedavisini tanımlamaktadır. On beş yaşındaki dişi Rus Toy Terrier ırkı bir köpek, mandibulasında sert bir kitle ve çiğneme güçlüğü şikâyetleriyle Afyon Kocatepe Üniversitesi Hayvan Hastanesi Cerrahi Kliniği’ne getirildi. Hastanın tıbbi öyküsünde, oral bölgede bulunan bir kitleye yönelik olarak Rusya’daki bir klinikte iki kez cerrahi operasyon geçirdiği belirtildi. Bu operasyonlarda çıkarılan kitlenin histopatolojik incelemesi, “akantomatöz ameloblastoma” veya “kanin akantomatöz epulis” tanısıyla raporlanmıştır. Rezeksiyon ameliyatlarından yaklaşık bir yıl sonra, mandibulada yeniden bir şişlik geliştiği bildirildi. Yapılan klinik muayenede, hastanın sol mandibular bölgesinde mandibulayı invaze eden sert bir kitle tespit edildi. Radyografik incelemede, kitlenin mandibulaya invazyonu doğrulandı ve kemikte osteolitik lezyonlar ortaya konuldu. Ayrıca kitlenin enfekte olduğu ve içinde irin biriktiği gözlendi. Kitleye yönelik radikal cerrahi rezeksiyon, parsiyel mandibulektomi ile gerçekleştirildi. Histopatolojik inceleme, yüksek dereceli sarkoma özellikleri taşıyan “iğsi hücreli fibrosarkom” ile uyumlu olup, köpeklerde yumuşak doku sarkomlarının derecelendirilmesine göre Grade III olarak sınıflandırıldı. Sonuç olarak, yazarların bilgisine göre bu olgu, ülkemizde Rus Toy Terrier ırkı bir köpekte cerrahi tedavisi tanımlanan ki ilk oral fibrosarkom vakasıdır.

Keywords

• Oral fibrosarkom
• Rus toy terrier
• Köpek

Oral Fibrosarcoma and It’s Surgical Treatment in A Russian Toy Terrier Dog

Abstract

This case report describes the surgical treatment of an oral fibrosarcoma in a Russian Toy Terrier. A 15-year-old female Russian Toy Terrier was presented to the Surgery Clinic at Afyon Kocatepe University Animal Hospital with a primary complaint of a hard mass in her jaw and difficulty chewing. The dog's medical history revealed she had two previous surgeries at a clinic in Russia that were performed by a separate surgical team prior to presentation at our facility for a mass in the oral region. The histopathological examination of the excised mass from those surgeries was diagnosed as acanthomatous ameloblastoma or canine acanthomatous epulis. It was reported that approximately one year after the resection surgeries, the dog was presented again with swelling in the lower jaw. The clinical examination revealed a hard mass in the patient's left mandibular region, invading the mandible. Radiography confirmed that the mass had invaded the mandible and showed osteolytic lesions in the bone. Additionally, the mass was infected, with pus accumulating within it. Radical surgical resection of the mass was performed through partial mandibulectomy. Histopathological examination showed a spindle cell fibrosarcoma with features of high-grade sarcoma, classified as Grade III according to canine soft tissue sarcoma grading. In conclusion, to the authors’ knowledge, this is the first reported case of oral fibrosarcoma in a Russian Toy Terrier dog, describing its surgical treatment in Türkiye.

Keywords

• Canine
• Mandibulectomy
• Oral fibrosarcoma
• Russian Toy Terrier.

References

1. Atalan, G., Atasever, A., Yavuz, Ü., Güneş, V., Onmaz, A. C. (2009). Kangal ırkı bir köpekte oral fibrosarkom olgusu. Fırat University Health Science Veterinary Journal, 23, 167–169.
2. Cray, M., Selmic, L. E., Ruple, A. (2020). Demographics of dogs and cats with oral tumours presenting to teaching hospitals: 1996–2017. Journal of Veterinary Science, 21(5), e70. https://doi.org/10.4142/jvs.2020.21.e70
3. Gardner, H., Fidel, J., Haldorson, G., Dernell, W., &Wheeler, B. (2015). Canine oral fibrosarcomas: A retrospective analysis of 65 cases (1998–2010). Veterinary and Comparative Oncology, 13(1), 40–47. https://doi.org/10.1111/vco.12017
4. Gaudio, E., Baines, E., Scurrell, E., Baines, S. (2024). Development of sialocoele following a mandibular rim excision for treatment of an oral fibrosarcoma in a dog. Veterinary Record Case Reports, 12(4), e928. https://doi.org/10.1002/vrc2.928
5. Kosovsky, J. K., Matthiesen, D. T., Marretta, S. M., Patnaik, A. K. (1991). Results of partial mandibulectomy for the treatment of oral tumours in 142 dogs. Veterinary Surgery, 20(6), 397–401. https://doi.org/10.1111/j.1532-950X.1991.tb00346.x
6. Kutsal, O., Kaya, Ü., Vural, S. A., Sağlam, M. (2003). A survey of bone tumours in dogs and cats from 1986 to 2000 in Ankara. Turkish Journal of Veterinary and Animal Sciences, 27(1), 109–115.
7. Lascelles, B. D. X., Henderson, R. A., Seguin, B., Liptak, J. M., Withrow, S. J. (2004). Bilateral rostral maxillectomy and nasal planectomy for large rostral maxillofacial neoplasms in six dogs and one cat. Journal of the American Animal Hospital Association, 40(2), 137–146. https://doi.org/10.5326/0400137
8. Martano, M., Iussich, S., Morello, E., Buracco, P. (2018). Canine oral fibrosarcoma: Changes in prognosis over the last 30 years. Veterinary Journal, 241, 1–7. https://doi.org/10.1016/j.tvjl.2018.09.005

9. Munday, J. S., Löhr, C. V., Kiupel, M. (2016). Tumours of the alimentary tract (5th ed.). John Wiley & Sons. https://doi.org/10.1002/9781119181200.ch13
10. Putnová, B., Burová, J., Georgiou, M., Fichtel, T., Stehlík, L., Frgelecová, L., & Škorič, M. (2020). Occurrence site of canine oral lesions: A retrospective study of 659 cases. Acta Veterinaria Brno, 89(2), 179–187. https://doi.org/10.2754/avb202089020179
11. Riggs, J., Adams, V.J., Hermer, J.V., Dobson, J.M., Murphy, S., Ladlow, J.F. (2018). Outcomes following surgical excision or surgical excision combined with adjunctive, hypofractionated radiotherapy in dogs with oral squamous cell carcinoma or fibrosarcoma. Journal of the American Veterinary Medical Association, 253(1), 73–83. https://doi.org/10.2460/javma.253.1.73
12. Satthathum, C., Srisampane, S., Jariyarangsrirattana, P., Anusorn, P., Sattasathuchana, P., & Thengchaisri, N. (2023). Characteristics of canine oral tumours: Insights into prevalence, types, and lesion distribution. Journal of Advanced Veterinary and Animal Research, 10(3), 554–562. http://doi.org/10.5455/javar.2023.j709
13. Simons, K. W. J. (2015). Oral tumours in dogs: A retrospective study of 110 cases (2002–2014) (Master’s thesis). Utrecht University, Clinical Sciences of Companion Animals, Netherlands.
14. Tanrisever, M., Karabulut, B., Çevik, A. (2020). A fibrosarcoma case with poor prognosis in a Golden Retriever breed dog. Fırat University Health Science Veterinary Journal, 34(2), 115–118.
15. Tsimitris, N. D., Kouki, M. I., Brellou, G. D., Papazoglou, L. G., Slini, T., Papadopoulou, P., & Papadimitriou, S. A. (2019). Canine oral neoplasms treated by surgical excision: Retrospective study of 63 cases. Hellenic Journal of Companion Animal Medicine, 8(1), 14–27.
16. Wallace, J., Matthiesen, D. T., Patnaik, A. K. (1992). Hemimaxillectomy for the treatment of oral tumours in 69 dogs. Veterinary Surgery, 21(5), 337–341. https://doi.org/10.1111/j.1532-950X.1992.tb01707.x