Bir Kedide İntrakranial Psammomatöz Meningioma Olgusu

Abstract

Bu çalışmada, halsizlik, kafasını sağa sola çarpma, yürümede güçlük, görmede bozukluk gibi klinik bulgularla ötenazisi yapılan, 17 yaşlı, erkek bir kedide intrakranial psammomatöz meningioma olgusu tanımlandı. Hayvan sahibinin isteği ile kedi ötenazi edildi.  Histolojik incelemede, atipik özellikler gösteren, mekik şekilli, belirgin eozinofilik sitoplazmalı, yuvarlak çekirdekli hücrelerin aralarında yoğun kollajen demetlerin varlığı görüldü. Ayrıca çok sayıda konsantrik lamellasyonlardan oluşan girdapların merkezlerinde bazofilik mineralizasyon alanlarının olduğu psammom adacıkları dikkati çekti. Bu yapıların aralarında yarıklar halinde kollesterin kristallerinin olduğu fark edildi. Sonuç olarak kedilerde sık rastlandığı bildirilen ancak ülkemizde ilk kez bir kedide saptanan intrakranial psammomatöz meningioma makroskobik ve mikroskobik bulguları ile tanımlanmıştır.

Keywords

• Histopatoloji,kedi,Psammomatöz meningioma

A Case of Intracranial Psammomatous Meningioma in A Cat

Abstract

In the present study, intracranial psammomatous meningioma was described in a 17 years old, male cat is submitted to clinics with history of weakness, incoordination, difficulty in walking and oversight. The animal is euthanatized with request of owner of cat. Histological examination revealed the presence of dense collagen bundles between the round nucleated cells with atypical features, shuttle-shaped, marked eosinophilic cytoplasm. In addition, psammom islands, where basophilic mineralization areas are located in the centers of vortices composed of many concentric lamellations, have been noted. At necropsy, the cadaver is evaluated systematically as to routin necropsy method. Collestrin clefts were seen between collestrin crystals. As a result, although intracranial psammomatous meningioma seen frequently in cats, the tumour was described with macroscopic and microscopic findings in a cat, in our country initially.

Keywords

• Cat,Histopathology,Psammomatous meningioma

References

1. Erer H, Kıran MM, 2005: Veteriner Onkoloji, Damla Ofset AŞ, Yeni Matbaacılar Sitesi, Konya, 126-127.
2. Forterre F, Tomek A, Konar M, Vandevelde M, Howard J, Jaggy A, 2007: Multiple meningomas: clinical, radyological, surgical and pathological findings with outcome in four cats. J Feline Med Surg, 9, 36-43.
3. Gül Y, İlhan F, 2010: Bir Sokak Kedisinde İntrakranial Transisyonel Meningiom Olgusu. YYU Veteriner Fakültesi Dergisi, 21,59-61
4. Koestner A, Bilzer T, Fatzer R, Schulman FY, Summers BA, Van Winkle TJ, 1999: Histological Classification of Tumors of the Nervous System of Domestic Animals. Armed Forces Institute of Pathology, The World Health Organization, Washington, DC, 27-29.
5. Koestner A, Higgins RJ, 2002: Tumors of the Nervous System. In: Tumors in Domestic Animals, Meuten DJ (Ed), Iowa State Pres, Ames, 717-723.
6. Lobetti RG, Nesbit JW, Miller DB, 1997: Multiple malignant meningiomas in a young cat. J S Afr Vet Assoc, 68, 62-65.
7. Patnaik AK, Kay WJ, Hurvitz AI, 1986: Intracranial meningioma: a comparative pathologic study of 28 dogs. Vet Pathol, 23, 369-373.
8. Summers BA, Cummings JF, Lahunta, 1995: Tumors of the central nervous system. In: Veterinary Neuropathology, Mosby-Year Book, St Louis, 351-401.

9. Tomek A, Cizinauskas S, Doherr M, Gandini G, Jaggy A, 2006: Intracranial neoplasia in 61 cats: localisation, tumour types and seizure patterns. J Feline Med Surg, 8, 243-253.
10. Troxel MT, Vite CH, Van Winkle TJ, Newton AL, Tiches D, Dayrell-Hart B, Kapatkin AS, Shofer FS, Steinberg, SA, 2003: Feline intracranial neoplasia: Retrospective rewiev of 160 cases (1985 – 2001). J Vet Intern Med, 17, 850-859.
11. Wills TB, Chen AV, Haldorson GJ, 2009: What is your diagnosis? Intracranial mass in a cat. Vet Clin Pathol, 38, 39-41.