Bir Ankara Kedisi’nde Malign Fibröz Histiositomun (Dev Hücreli Tip) İnce İğne Aspirasyon Sitolojisi

Yıl 2018, , 130 - 132, 04.07.2018

Nihat Yumusak , Murat Calıskan Osman Kutsal

https://doi.org/10.31196/huvfd.470993

Öz

Bu olguda, 9 yaşlı, Ankara ırkı, dişi bir kedinin
sırtında radyolojik, sitopatolojik ve histopatolojik olarak dev hücreli malign
fibröz histiyositoma olgusu tanımlandı. Latero-lateral ve ventro-dorsal olarak  tümöral kitlenin invazyonu radyolojik olarak
belirlendi. Radyolojik incelemede kitle invaziv görüntüde olup kemiğe
bağlantısı yoktu.  Genel anestezi altında
tümöral bölgeden İnce İğne Aspirasyon Sitolojisi (İİAS) tekniğine göre
sitopatolojik örnekler alınarak May-Grunwald Giemsa yöntemine göre boyandı.
Cerrahi operasyonla uzaklaştırılan biyopsi örneği ise rutin doku takibine
alınarak hematoksilen eosin (HE) ile boyandı. Biyopsi materyali 8x6x6 cm ve 95
gr ağırlığında, deriyle kaplı, multilobuler yapıda ve sert kıvamlıydı. Kesit
yüzü gri beyaz ve nekrotik manzaradaydı. Sitopatolojik incelemelerde anaplazik
özelliklerde, pleomorfik şekilli histiyosit benzeri yada fibrosit benzeri çok
sayıda hücreyle beraber, geniş ve vakuoler sitoplazmalı, çok çekirdekli dev
hücreleri dikkati çekti. Histolojik incelemelerde ise, çeşitli yönlere
girdaplar şeklinde dizilim yapmış atipik özellikler gösteren histiyosit benzeri
veya bağ dokusu hücrelerinin aralarında, çok sayıda, geniş sitoplazmalı, 8-12
çekirdekli dev hücreleri fark edildi.

Anahtar Kelimeler

Kedi, Sitoloji, Radyoloji, Histopatoloji, Malign fibröz histiositom

Fine-Needle Aspiration Cytology of Malignant Fibrous Histiocytoma (Giant Cell Type) in an Angora Cat

Öz

This case study presents the radiological,
cytopathological and histopathological description of the giant cell type of a
malignant fibrous histiocytoma on the back of a 9-year-old female Angora cat. Latero-lateral
and ventro-dorsal thoracic radiographs was taken to evaluate invasion. Radiologically
the mass was invasive but had not invaded the bone. Under general anaesthesia,
cytopathological samples were taken from the tumour, using the Fine-Needle
Aspiration Cytology (FNAC)
technique, and were later stained with May-Grünwald Giemsa solution. The
surgically extracted biopsy sample was subjected to routine tissue processing
and stained with Haematoxylin-Eosin (HE). The biopsy material was 8x6x6 cm and
95 g, was covered by skin, multilobulary appearance and hard consistency.
Cross-sections was greyish white and necrotic appearance. Cytopathological
examination revealed the presence of numerous histiocyte- or fibrocyte-like
cells of anaplastic character and pleomorphic shape, which were associated with
giant cells with multiple nuclei and a broad and vacuolar cytoplasm.
Histological examination demonstrated the presence of histiocyte-like atypical
cells arranged in the form of swirls and extending in various directions, or
numerous giant cells with 8 to 12 nuclei and a broad cytoplasm situated in
between connective tissue cells.

Anahtar Kelimeler

Cat, Cytology, Radiology, Histopathology, Malignant fibrous histiocytoma

Kaynakça

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