Yıl 2019, Cilt 4 , Sayı 2, Sayfalar 145 - 150 2019-08-27

CARRIERS OF CHROMOSOME TRANSLOCATIONS FROM THREE MEN WITH AZOOSPERMIA

Gülbahar GÜZEL ERDAL [1] , Mahmut BALKAN [2]


Male infertility is liable for half of the genetic infertility cases. Robertsonian and Reciprocal translocations are the major chromosomal rearrangements in the infertile population. In this study, we aimed to submit a Robertsonian and two Reciprocal translocations in three couples with a history of male infertility with azoospermia. Chromosomal analysis of the one couple in the male partner appeared with an abnormal karyotype with 45, XY, rob (13,14) chromosomal constitution, while the female partner revealed normal 46, XX karyotype. The other two couple revealed in the male partner with reciprocal translocations, while the female partners showed normal 46, XX karyotype; one of infertile males has karyotype with 46,XY, rcp (19:10), and other infertile male with 46,XY,rcp(6:14) chromosomal constitution. The cytogenetic analysis is mandatory to identify any probable chromosomal anomalies for couples with primer infertility. Couples with repeated abortions should be offered prenatal diagnosis in the case of future pregnancies. Chromosome translocation carriers should be counseled to use advanced technologies such as assisted reproductive technology such as PGD.

male infertility, chromosome abnormalities
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Birincil Dil en
Konular Biyokimya ve Moleküler Biyoloji
Bölüm Case Report
Yazarlar

Orcid: 0000-0003-0138-6622
Yazar: Gülbahar GÜZEL ERDAL (Sorumlu Yazar)
Kurum: DICLE UNIVERSITY
Ülke: Turkey


Orcid: 0000-0003-0138-6622
Yazar: Mahmut BALKAN (Sorumlu Yazar)
Kurum: DICLE UNIVERSITY
Ülke: Turkey


Destekleyen Kurum Dicle University Research Fund DUBAP, Project No. TIP.18.036.
Proje Numarası TIP.18.036
Tarihler

Başvuru Tarihi : 19 Ağustos 2019
Kabul Tarihi : 27 Ağustos 2019
Yayımlanma Tarihi : 27 Ağustos 2019

Bibtex @olgu sunumu { ijhsrp606830, journal = {International Journal of Health Services Research and Policy}, issn = {}, eissn = {2602-3482}, address = {Dicle Üniversitesi Teknokenti Silvan Bulvarı 222/3 21280 SUR/DİYARBAKIR}, publisher = {Rojan GÜMÜŞ}, year = {2019}, volume = {4}, pages = {145 - 150}, doi = {10.23884/ijhsrp.2019.4.2.08}, title = {CARRIERS OF CHROMOSOME TRANSLOCATIONS FROM THREE MEN WITH AZOOSPERMIA}, key = {cite}, author = {Güzel Erdal, Gülbahar and Balkan, Mahmut} }
APA Güzel Erdal, G , Balkan, M . (2019). CARRIERS OF CHROMOSOME TRANSLOCATIONS FROM THREE MEN WITH AZOOSPERMIA . International Journal of Health Services Research and Policy , 4 (2) , 145-150 . DOI: 10.23884/ijhsrp.2019.4.2.08
MLA Güzel Erdal, G , Balkan, M . "CARRIERS OF CHROMOSOME TRANSLOCATIONS FROM THREE MEN WITH AZOOSPERMIA" . International Journal of Health Services Research and Policy 4 (2019 ): 145-150 <https://dergipark.org.tr/tr/pub/ijhsrp/issue/48345/606830>
Chicago Güzel Erdal, G , Balkan, M . "CARRIERS OF CHROMOSOME TRANSLOCATIONS FROM THREE MEN WITH AZOOSPERMIA". International Journal of Health Services Research and Policy 4 (2019 ): 145-150
RIS TY - JOUR T1 - CARRIERS OF CHROMOSOME TRANSLOCATIONS FROM THREE MEN WITH AZOOSPERMIA AU - Gülbahar Güzel Erdal , Mahmut Balkan Y1 - 2019 PY - 2019 N1 - doi: 10.23884/ijhsrp.2019.4.2.08 DO - 10.23884/ijhsrp.2019.4.2.08 T2 - International Journal of Health Services Research and Policy JF - Journal JO - JOR SP - 145 EP - 150 VL - 4 IS - 2 SN - -2602-3482 M3 - doi: 10.23884/ijhsrp.2019.4.2.08 UR - https://doi.org/10.23884/ijhsrp.2019.4.2.08 Y2 - 2019 ER -
EndNote %0 International Journal of Health Services Research and Policy CARRIERS OF CHROMOSOME TRANSLOCATIONS FROM THREE MEN WITH AZOOSPERMIA %A Gülbahar Güzel Erdal , Mahmut Balkan %T CARRIERS OF CHROMOSOME TRANSLOCATIONS FROM THREE MEN WITH AZOOSPERMIA %D 2019 %J International Journal of Health Services Research and Policy %P -2602-3482 %V 4 %N 2 %R doi: 10.23884/ijhsrp.2019.4.2.08 %U 10.23884/ijhsrp.2019.4.2.08
ISNAD Güzel Erdal, Gülbahar , Balkan, Mahmut . "CARRIERS OF CHROMOSOME TRANSLOCATIONS FROM THREE MEN WITH AZOOSPERMIA". International Journal of Health Services Research and Policy 4 / 2 (Ağustos 2019): 145-150 . https://doi.org/10.23884/ijhsrp.2019.4.2.08
AMA Güzel Erdal G , Balkan M . CARRIERS OF CHROMOSOME TRANSLOCATIONS FROM THREE MEN WITH AZOOSPERMIA. IJHSRP. 2019; 4(2): 145-150.
Vancouver Güzel Erdal G , Balkan M . CARRIERS OF CHROMOSOME TRANSLOCATIONS FROM THREE MEN WITH AZOOSPERMIA. International Journal of Health Services Research and Policy. 2019; 4(2): 145-150.