Abstract
Marrubium vulgare L. is a perennial herbaceous plant belonging to the Lamiaceae family. This species, which usually grows in regions with a Mediterranean climate, has gray-green hairy leaves and small white flowers. It is widely used in traditional medicine in the treatment of respiratory diseases, digestive problems and cough. M. vulgare has a strong antioxidant capacity thanks to the phenolic compounds, flavonoids and diterpenoids it contains. Thanks to these properties, it is among the plants that attract attention in the pharmaceutical and food industries as a natural antioxidant source. The ethanol: water extract exhibited higher antioxidant capacity than the ethanol extract, as evidenced by its stronger DPPH radical scavenging activity (61.60%), greater CUPRAC value (4.36 mM Trolox equivalents/mg extract), and enhanced FRAP reducing power (0.64 mM FeSO₄/mg extract). The total phenolic content was found to be comparable between the two extracts. As expected, the reference antioxidants ascorbic acid and demonstrated superior antioxidant activities compared to the plant extracts. In enzyme inhibition analyses, the ethanol extract showed more pronounced anticholinesterase activity (20.911±2.324), while the ethanol: water extract showed higher antiurease inhibition (27.615±2.092). Overall, the findings indicate that the solvent system significantly affects the biological activity profile of M. vulgare.
Keywords
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Details
| Primary Language | English |
|---|---|
| Subjects | Botany (Other) |
| Journal Section | Research Article |
| Authors | |
| Submission Date | February 22, 2026 |
| Acceptance Date | March 11, 2026 |
| Early Pub Date | March 26, 2026 |
| Publication Date | March 26, 2026 |
| IZ | https://izlik.org/JA86DM22WN |
| Published in Issue | Year 2026 Issue: Advanced Online Publication |
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- Erdem, F., Doğan, G., Kıran, Y., & Evren, H. (2017). Morphological, anatomical, palynological and karyological characters of endemic Sideritis vulcanica (Lamiaceae) from Turkey. International Journal of Nature Life Sciences, 1 (1), 1-11.
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