The Algerian endemic plant Ammoides atlantica (Coss. et Durieu) H. Wolff was studied for the chemical profiling and biological activities of its essential oil (EO) and ethanolic extract (EE). The chemical analysis by GC/MS and HPLC/DAD/UV revealed, respectively, the major compounds thymol (39.46%), γ-terpinene (31.74%), and p-cymene (19.01%) in the EO, and apigenin (33.58%), luteolin 7-O-glucoside (20.09%), and luteolin (14.39%) in the EE. The EO exhibited strong antioxidant activity, with a significant ABTS•+ scavenging capacity (IC50 = 2.79 µg/mL) compared to EE, Trolox, and BHT. The EE showed comparable effects to BHT in DPPH scavenging and reducing power tests. Moreover, the EO demonstrated noteworthy antibacterial activity against S. aureus, E. coli, and P. aeruginosa, with inhibition zone diameters ranging from 32.1 to 70 mm and MICs below 0.3 to 5 mg/mL. Furthermore, the EE exhibited strong anti-inflammatory activity by inhibiting hemolysis of red blood cells >70% at a concentration of 20 µg/mL.
Ammoides atlantica Essential oil Ethanolic extract Chemical profiling Bioactivity
This research was supported by the University of Algiers 1 Benyoucef Benkhedda and the National Higher School of Agronomy as part of a University Training Research Project (PRFU).
Project number: D01N01ES160320220001
The Algerian endemic plant Ammoides atlantica (Coss. et Durieu) H. Wolff was studied for the chemical profiling and biological activities of its essential oil (EO) and ethanolic extract (EE). The chemical analysis by GC/MS and HPLC/DAD/UV revealed, respectively, the major compounds thymol (39.46%), γ-terpinene (31.74%), and p-cymene (19.01%) in the EO, and apigenin (33.58%), luteolin 7-O-glucoside (20.09%), and luteolin (14.39%) in the EE. The EO exhibited strong antioxidant activity, with a significant ABTS•+ scavenging capacity (IC50 = 2.79 µg/mL) compared to EE, Trolox, and BHT. The EE showed comparable effects to BHT in DPPH scavenging and reducing power tests. Moreover, the EO demonstrated noteworthy antibacterial activity against S. aureus, E. coli, and P. aeruginosa, with inhibition zone diameters ranging from 32.1 to 70 mm and MICs below 0.3 to 5 mg/mL. Furthermore, the EE exhibited strong anti-inflammatory activity by inhibiting hemolysis of red blood cells >70% at a concentration of 20 µg/mL.
Ammoides atlantica Essential oil Ethanolic extract Chemical profiling Bioactivity
This research was supported by the University of Algiers 1 Benyoucef Benkhedda and the National Higher School of Agronomy as part of a University Training Research Project (PRFU).
Project number: D01N01ES160320220001
Birincil Dil | İngilizce |
---|---|
Konular | Doğal Ürünler ve Biyoaktif Bileşikler |
Bölüm | Makaleler |
Yazarlar | |
Proje Numarası | Project number: D01N01ES160320220001 |
Erken Görünüm Tarihi | 8 Ekim 2024 |
Yayımlanma Tarihi | |
Gönderilme Tarihi | 7 Mart 2024 |
Kabul Tarihi | 4 Temmuz 2024 |
Yayımlandığı Sayı | Yıl 2024 Cilt: 11 Sayı: 4 |