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Clinical Characteristics and Geriatric Nutritional Risk Index Levels in Elderly People with Dementia Living in A Nursing Home

Yıl 2022, Cilt: 6 Sayı: 1, 35 - 41, 15.07.2022

Öz

ge, gender, family history, low education level, hypertension, diabetes, hyperlipidemia, smoking, alcohol and vitamin D deficiency are thought to be potential risk factors for patients with dementia. In addition, malnutrition is common among dementia patients. Therefore, we aimed to evaluate the clinical characteristics and Geriatric Nutritional Risk Index (GNRI) status of elderly individuals living in a nursing home diagnosed with dementia alongside those without dementia. A total of 150 elderly individuals aged 60 and over living in an Istanbul nursing home in were included in the study. Demographic characteristics, comorbidity status, and biochemical parameters were obtained from their own files. In addition, the GNRI status of elderly individuals were calculated. The mean age of patients with dementia is higher than those without (p <0.05). The number of illiterate elderly (41.3%) was higher in those with dementia (p <0.05). The mean Body Mass Index (BMI) and serum glucose, ALT, and albumin in the elderly were significantly lower in those with dementia (p <0.05). When GNRI valueswere compared, those with dementia were at a higher risk than those without (70.7%, 33.3%, respectively). Findings call for a multidimensional assessment of the health status of elderly individuals living in nursing homes.

Kaynakça

  • [1]American Psychiatric Association (APA), Diagnostic and statistical manual of mental disorders: DSM-5. Washington, D.C: American Psychiatric Association(2013).
  • [2]Huq AJ, Sexton A, Lacaze P, Masters CL, Storey E, Velakoulis D, et al. Genetic testing in dementia‐A medical genetics perspective. International Journal of Geriatric Psychiatry(2021) 36(8):1158–1170. doi:10.1002/gps.5535.
  • [3]Lee S, Cho E-J, Kwak H-B. Personalized Healthcare for Dementia. Healthcare(2021) 9(2):128. doi:10.3390/healthcare9020128.
  • [4]Jayedi A, Rashidy-Pour A, Shab-Bidar S. Vitamin D status and risk of dementia and Alzheimer’s disease: A meta-analysis of dose-response. Nutritional Neuroscience(2019) 22(11):750–759. doi:10.1080/1028415X.2018.1436639.
  • [5]Alzheimer’s Disease International (ADI). World Alzheimer Report 2021 Journey Through the diagnosis of dementia. London: Alzheimer’s Disease Internationa(2021). Available at: https://www.alzint.org/u/World.
  • [6]Karakis I, Pase MP, Beiser A, Booth SL, Jacques PF, Rogers G, et al. Association of Serum Vitamin D with the Risk of Incident Dementia and Subclinical Indices of Brain Aging: The Framingham Heart Study. Journal of Alzheimer's Disease(2016) 51(2):451–461. doi:10.3233/JAD-150991.
  • [7]Norton S, Matthews FE, Barnes DE, Yaffe K, Brayne C. Potential for primary prevention of Alzheimer's disease: an analysis of population-based data. The Lancet Neurology(2014) 13(8):788–794. doi:10.1016/S1474-4422(14)70136-X.
  • [8]Ames BN, Grant WB, Willett WC. Does the High Prevalence of Vitamin D Deficiency in African Americans Contribute to Health Disparities? Nutrients(2021) 13(2):499. doi:10.3390/nu13020499.
  • [9]ADI. Policy Brief Risk Factors For Dementia. London: Alzheimer’s Disease International 2012, Available at: https://www.alz.co.uk/sites/default/files/policy-brief-risk-factors-for-dementia.pdf(2021).
  • [10]Brook S. Nutrition and dementia: what can we do to help? BritishJournal of Community Nursing(2014) 19(Sup11):S24-S27. doi:10.12968/bjcn.2014.19.Sup11.S24.
  • [11]Sanders CL, Wengreen HJ, Schwartz S, Behrens SJ, Corcoran C, Lyketsos CG, et al. Nutritional Status is Associated With Severe Dementia and Mortality. Alzheimer Disease & Associated Disorders(2018) 32(4):298–304. doi:10.1097/WAD.0000000000000274.
  • [12]Bouillanne O, Morineau G, Dupont C, Coulombel I, Vincent J-P, Nicolis I, et al. Geriatric Nutritional Risk Index: a new index for evaluating at-risk elderly medical patients. The American Journal of Clinical Nutrition(2005) 82(4):777–783. doi:10.1093/ajcn/82.4.777.
  • [13]Xiong J, Wang M, Zhang Y, Nie L, He T, Wang Y, et al. Association of Geriatric Nutritional Risk Index with Mortality in Hemodialysis Patients: A Meta-Analysis of Cohort Studies. Kidney and Blood Pressure Research(2018) 43(6):1878–1889. doi:10.1159/000495999.
  • [14]World Health Organization. Body Mass Index (BMI).
  • [15]Buell JS, Dawson-Hughes B, Scott TM, Weiner DE, Dallal GE, Qui WQ, et al. 25-Hydroxyvitamin D, dementia, and cerebrovascular pathology in elders receiving home services. Neurology(2010) 74(1):18–26. doi:10.1212/WNL.0b013e3181beecb7.
  • [16]Bakır MA, Aydın C. Statistics. 6. Edition. Ankara: Nobel publications, ISBN; 6051330129(2015). 215p.
  • [17]TUIK. Elderly with statistics. Sayı: 33712. Turkey: Turkish Statistical Institute 2015, Available at: http://www.tuik.gov.tr/HbPrint.do?id=33712. [Accessed June 2021].
  • [18]United Nations (UN). Department of Economic and Social Affairs. World Population Ageing 2019. New York: United Nations 2019, Available at: https://www.un.org/development/desa/pd/sites/www.un.org.development.desa.pd/files/files/documents/2020/Jan/worldpopu.
  • [19]Hersi M, Irvine B, Gupta P, Gomes J, Birkett N, Krewski D. Risk factors associated with the onset and progression of Alzheimer’s disease: A systematic review of the evidence. NeuroToxicology(2017) 61:143–187. doi:10.1016/j.neuro.2017.03.006.
  • [20]Silva MVF, Loures, Cristina de Mello Gomide, Alves LCV, Souza LC de, Borges KBG, Carvalho MdG. Alzheimer’s disease: risk factors and potentially protective measures. Journal of Biomedical Science(2019) 26(1):33. doi:10.1186/s12929-019-0524-y.
  • [21]Wahl D, Solon-Biet SM, Cogger VC, Fontana L, Simpson SJ, Le Couteur DG, et al. Aging, lifestyle and dementia. Neurobiology of Disease(2019) 130:104481. doi:10.1016/j.nbd.2019.104481.
  • [22]Chêne G, Beiser A, Au R, Preis SR, Wolf PA, Dufouil C, et al. Gender and incidenceof dementia in the Framingham Heart Study from mid‐adult life. Alzheimer's & Dementia(2015) 11(3):310–320. doi:10.1016/j.jalz.2013.10.005.
  • [23]Lee S-Y, Lim J-S, Oh DJ, Kong IG, Choi HG. Increased risk of neurodegenerative dementia in women with migraines. Medicine(2019) 98(7):e14467-e14467. doi:10.1097/MD.0000000000014467.
  • [24]Viña J, Lloret A, Zhu X, Beal MF, Wang X, Perry G, et al. Why Women Have More Alzheimer's Disease Than Men: Gender and Mitochondrial Toxicity of Amyloid-β Peptide. Journal of Alzheimer's Disease(2010) 20(s2):S527-S533. doi:10.3233/JAD-2010-100501.
  • [25]Scheyer O, Rahman A, Hristov H, Berkowitz C, Isaacson RS, Diaz Brinton R, et al. Female Sex and Alzheimer’s Risk: The Menopause Connection. The Journal Of Prevention of Alzheimer'sDisease(2018):1–6. doi:10.14283/jpad.2018.34.
  • [26]Contador I, Del Ser T, Llamas S, Villarejo A, Benito-León J, Bermejo-Pareja F. Impact of literacy and years of education on the diagnosis of dementia: A population-based study. Journal of Clinical and Experimental Neuropsychology(2017) 39(2):112–119. doi:10.1080/13803395.2016.1204992.
  • [27]Lipnicki DM, Makkar SR, Crawford JD, Thalamuthu A, Kochan NA, Lima-Costa MF, et al. Determinants of cognitive performance and decline in 20 diverse ethno-regional groups: A COSMIC collaboration cohort study. PLOS Medicine(2019) 16(7):e1002853-e1002853. doi:10.1371/journal.pmed.1002853.
  • [28]Xu W, Tan L, Wang H-F, Tan M-S, Tan L, Li J-Q, et al. Education and Risk of Dementia: Dose-Response Meta-Analysis of Prospective Cohort Studies. Molecular Neurobiology(2016) 53(5):3113–3123. doi:10.1007/s12035-015-9211-5.
  • [29]Ulstein I, Bøhmer T. Normal Vitamin Levels and Nutritional Indices in Alzheimer’s Disease Patients with Mild Cognitive Impairment or Dementia with Normal BodyMass Indexes. Journal of Alzheimer's Disease(2016) 55(2):717–725. doi:10.3233/JAD-160393.
  • [30]Galesi LF, Leandro-Merhi VA, Oliveira MRM de. Association between indicators of dementia and nutritional status in institutionalised older people. International Journal of Older People Nursing(2013) 8(3):236–243. doi:10.1111/j.1748-3743.2012.00321.x.
  • [31]Lee CM, Woodward M, Batty GD, Beiser AS, Bell S, Berr C, et al. Association of anthropometry and weight change with risk of dementia and its major subtypes: Ameta‐analysis consisting 2.8 million adults with 57 294 cases of dementia. Obesity Reviews(2020) 21(4). doi:10.1111/obr.12989.
  • [32]Walrand S. Dietary supplement intake among the elderly. Current Opinion in Clinical Nutrition & Metabolic Care(2018) 21(6):465–470. doi:10.1097/MCO.0000000000000512.
  • [33]Mutt SJ, Jokelainen J, Sebert S, Auvinen J, Järvelin M-R, Keinänen-Kiukaanniemi S, et al. Vitamin D Status and Components of Metabolic Syndrome in Older Subjects from Northern Finland (Latitude 65°North). Nutrients(2019) 11(6):1229. doi:10.3390/nu11061229.
  • [34]Steingrimsdottir L. Relationship Between Serum Parathyroid Hormone Levels, Vitamin D Sufficiency, and Calcium Intake. JAMA(2005) 294(18):2336. doi:10.1001/jama.294.18.2336.
  • [35]NIH. Vitamin D Fact Sheet for Health Professionals. Washington, D.C: National Institutes of Health, 2021, Available at: https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/. [Accessed January 2022].
  • [36]Pettersen JA. Does high dose vitamin D supplementation enhancecognition? A randomized trial in healthy adults. Experimental Gerontology(2017) 90:90–97. doi:10.1016/j.exger.2017.01.019.
  • [37]Löppönen MK, Isoaho RE, Räihä IJ, Vahlberg TJ, Loikas SM, Takala TI, et al. Undiagnosed Diseases in Patients with Dementia –APotential Target Group for Intervention. Dementia and Geriatric Cognitive Disorders(2004) 18(3-4):321–329. doi:10.1159/000080126.
  • [38]Reitz C, Brickman AM, Luchsinger JA, Wu WE, Small SA, Tang M-X, et al. Frequency of Subclinical Heart Disease in Elderly Persons With Dementia. The American Journal of Geriatric Cardiology(2007) 16(3):183–188. doi:10.1111/j.1076-7460.2007.06511.x.
  • [39]Alzheimer’s and Dementia. 2021 Alzheimer’s Disease Facts And Figures. Alzheimer’s and Dementia. Chicago: Alzheimer’s Association 2021, Available at: https://www.alz.org/media/Documents/alzheimers-facts-and-figures.pdf. [Accessed January 2022].
  • [40]Ramdane S, Daoudi-Gueddah D. Mild Hypercholesterolemia, Normal Plasma Triglycerides, and Normal Glucose Levels Across Dementia Staging in Alzheimer’s Disease. American Journal of Alzheimer's Disease & Other Dementiasr(2011) 26(5):399–405. doi:10.1177/1533317511414552.
  • [41]Moretti R, Caruso P, Dal Ben M, Conti C, Gazzin S, Tiribelli C. Vitamin D, Homocysteine, and Folate in Subcortical Vascular Dementia and Alzheimer Dementia. Frontiers in Aging Neuroscience(2017) 9. doi:10.3389/fnagi.2017.00169.
  • [42]Yeşil Y, Kuyumcu ME, Kara Ö, Halaçlı B, Etgül S, Kızılarslanoğlu MC, et al. Vitamin D status and its association with gradual decline in cognitive function. Turkish Journal of Medica Sciences(2015) 45:1051–1057. doi:10.3906/sag-1405-11.
  • [43]Llewellyn DJ, Langa KM, Friedland RP, Lang IA. Serum albumin concentration and cognitive impairment. Current Alzheimer research(2010) 7(1):91–96. doi:10.2174/156720510790274392.
  • [44]Liu W, Cheon J, Thomas SA. Interventions on mealtime difficulties in older adults with dementia: A systematic review. International Journal of Nursing Studies(2014) 51(1):14–27. doi:10.1016/j.ijnurstu.2012.12.021.
  • [45]Gschwind YJ, Bischoff-Ferrari HA, Bridenbaugh SA, Härdi I, Kressig RW. Association between Serum Vitamin D Status and Functional Mobility in Memory Clinic Patients Aged 65 Years and Older. Gerontology(2014) 60(2):123–129. doi:10.1159/000355667.
  • [46]Feart C, Helmer C, Merle B, Herrmann FR, Annweiler C, Dartigues J-F, et al. Associations of lower vitamin D concentrations with cognitive decline and long‐term risk of dementia and Alzheimer's disease in older adults. Alzheimer's & Dementia(2017) 13(11):1207–1216. doi:10.1016/j.jalz.2017.03.003.
  • [47]Lee KS, Hong CH, Cheong H-K, Oh BH. Difference in nutritional risk between mild cognitive impairment group and normal cognitive function elderly group. Archives of Gerontology and Geriatrics(2009) 49(1):49–53.doi:10.1016/j.archger.2008.04.011.
  • [48]Camina MM, Barrera SO, Domínguez LR, Couceiro CM, Del Río Redondo MP. Presence of malnutrition and risk of malnutrition in institutionalized elderly with dementia according to the type and deterioration stage. Nutr.Hosp.(2012) 27:434–440. doi:10.1590/s0212-16112012000200013.
  • [49]Lee KS, Cheong H-K, Kim EA, Kim KR, Oh BH, Hong CH. Nutritional risk and cognitive impairment in the elderly. Archives of Gerontology and Geriatrics(2009) 48(1):95–99. doi:10.1016/j.archger.2007.11.001.
Yıl 2022, Cilt: 6 Sayı: 1, 35 - 41, 15.07.2022

Öz

Kaynakça

  • [1]American Psychiatric Association (APA), Diagnostic and statistical manual of mental disorders: DSM-5. Washington, D.C: American Psychiatric Association(2013).
  • [2]Huq AJ, Sexton A, Lacaze P, Masters CL, Storey E, Velakoulis D, et al. Genetic testing in dementia‐A medical genetics perspective. International Journal of Geriatric Psychiatry(2021) 36(8):1158–1170. doi:10.1002/gps.5535.
  • [3]Lee S, Cho E-J, Kwak H-B. Personalized Healthcare for Dementia. Healthcare(2021) 9(2):128. doi:10.3390/healthcare9020128.
  • [4]Jayedi A, Rashidy-Pour A, Shab-Bidar S. Vitamin D status and risk of dementia and Alzheimer’s disease: A meta-analysis of dose-response. Nutritional Neuroscience(2019) 22(11):750–759. doi:10.1080/1028415X.2018.1436639.
  • [5]Alzheimer’s Disease International (ADI). World Alzheimer Report 2021 Journey Through the diagnosis of dementia. London: Alzheimer’s Disease Internationa(2021). Available at: https://www.alzint.org/u/World.
  • [6]Karakis I, Pase MP, Beiser A, Booth SL, Jacques PF, Rogers G, et al. Association of Serum Vitamin D with the Risk of Incident Dementia and Subclinical Indices of Brain Aging: The Framingham Heart Study. Journal of Alzheimer's Disease(2016) 51(2):451–461. doi:10.3233/JAD-150991.
  • [7]Norton S, Matthews FE, Barnes DE, Yaffe K, Brayne C. Potential for primary prevention of Alzheimer's disease: an analysis of population-based data. The Lancet Neurology(2014) 13(8):788–794. doi:10.1016/S1474-4422(14)70136-X.
  • [8]Ames BN, Grant WB, Willett WC. Does the High Prevalence of Vitamin D Deficiency in African Americans Contribute to Health Disparities? Nutrients(2021) 13(2):499. doi:10.3390/nu13020499.
  • [9]ADI. Policy Brief Risk Factors For Dementia. London: Alzheimer’s Disease International 2012, Available at: https://www.alz.co.uk/sites/default/files/policy-brief-risk-factors-for-dementia.pdf(2021).
  • [10]Brook S. Nutrition and dementia: what can we do to help? BritishJournal of Community Nursing(2014) 19(Sup11):S24-S27. doi:10.12968/bjcn.2014.19.Sup11.S24.
  • [11]Sanders CL, Wengreen HJ, Schwartz S, Behrens SJ, Corcoran C, Lyketsos CG, et al. Nutritional Status is Associated With Severe Dementia and Mortality. Alzheimer Disease & Associated Disorders(2018) 32(4):298–304. doi:10.1097/WAD.0000000000000274.
  • [12]Bouillanne O, Morineau G, Dupont C, Coulombel I, Vincent J-P, Nicolis I, et al. Geriatric Nutritional Risk Index: a new index for evaluating at-risk elderly medical patients. The American Journal of Clinical Nutrition(2005) 82(4):777–783. doi:10.1093/ajcn/82.4.777.
  • [13]Xiong J, Wang M, Zhang Y, Nie L, He T, Wang Y, et al. Association of Geriatric Nutritional Risk Index with Mortality in Hemodialysis Patients: A Meta-Analysis of Cohort Studies. Kidney and Blood Pressure Research(2018) 43(6):1878–1889. doi:10.1159/000495999.
  • [14]World Health Organization. Body Mass Index (BMI).
  • [15]Buell JS, Dawson-Hughes B, Scott TM, Weiner DE, Dallal GE, Qui WQ, et al. 25-Hydroxyvitamin D, dementia, and cerebrovascular pathology in elders receiving home services. Neurology(2010) 74(1):18–26. doi:10.1212/WNL.0b013e3181beecb7.
  • [16]Bakır MA, Aydın C. Statistics. 6. Edition. Ankara: Nobel publications, ISBN; 6051330129(2015). 215p.
  • [17]TUIK. Elderly with statistics. Sayı: 33712. Turkey: Turkish Statistical Institute 2015, Available at: http://www.tuik.gov.tr/HbPrint.do?id=33712. [Accessed June 2021].
  • [18]United Nations (UN). Department of Economic and Social Affairs. World Population Ageing 2019. New York: United Nations 2019, Available at: https://www.un.org/development/desa/pd/sites/www.un.org.development.desa.pd/files/files/documents/2020/Jan/worldpopu.
  • [19]Hersi M, Irvine B, Gupta P, Gomes J, Birkett N, Krewski D. Risk factors associated with the onset and progression of Alzheimer’s disease: A systematic review of the evidence. NeuroToxicology(2017) 61:143–187. doi:10.1016/j.neuro.2017.03.006.
  • [20]Silva MVF, Loures, Cristina de Mello Gomide, Alves LCV, Souza LC de, Borges KBG, Carvalho MdG. Alzheimer’s disease: risk factors and potentially protective measures. Journal of Biomedical Science(2019) 26(1):33. doi:10.1186/s12929-019-0524-y.
  • [21]Wahl D, Solon-Biet SM, Cogger VC, Fontana L, Simpson SJ, Le Couteur DG, et al. Aging, lifestyle and dementia. Neurobiology of Disease(2019) 130:104481. doi:10.1016/j.nbd.2019.104481.
  • [22]Chêne G, Beiser A, Au R, Preis SR, Wolf PA, Dufouil C, et al. Gender and incidenceof dementia in the Framingham Heart Study from mid‐adult life. Alzheimer's & Dementia(2015) 11(3):310–320. doi:10.1016/j.jalz.2013.10.005.
  • [23]Lee S-Y, Lim J-S, Oh DJ, Kong IG, Choi HG. Increased risk of neurodegenerative dementia in women with migraines. Medicine(2019) 98(7):e14467-e14467. doi:10.1097/MD.0000000000014467.
  • [24]Viña J, Lloret A, Zhu X, Beal MF, Wang X, Perry G, et al. Why Women Have More Alzheimer's Disease Than Men: Gender and Mitochondrial Toxicity of Amyloid-β Peptide. Journal of Alzheimer's Disease(2010) 20(s2):S527-S533. doi:10.3233/JAD-2010-100501.
  • [25]Scheyer O, Rahman A, Hristov H, Berkowitz C, Isaacson RS, Diaz Brinton R, et al. Female Sex and Alzheimer’s Risk: The Menopause Connection. The Journal Of Prevention of Alzheimer'sDisease(2018):1–6. doi:10.14283/jpad.2018.34.
  • [26]Contador I, Del Ser T, Llamas S, Villarejo A, Benito-León J, Bermejo-Pareja F. Impact of literacy and years of education on the diagnosis of dementia: A population-based study. Journal of Clinical and Experimental Neuropsychology(2017) 39(2):112–119. doi:10.1080/13803395.2016.1204992.
  • [27]Lipnicki DM, Makkar SR, Crawford JD, Thalamuthu A, Kochan NA, Lima-Costa MF, et al. Determinants of cognitive performance and decline in 20 diverse ethno-regional groups: A COSMIC collaboration cohort study. PLOS Medicine(2019) 16(7):e1002853-e1002853. doi:10.1371/journal.pmed.1002853.
  • [28]Xu W, Tan L, Wang H-F, Tan M-S, Tan L, Li J-Q, et al. Education and Risk of Dementia: Dose-Response Meta-Analysis of Prospective Cohort Studies. Molecular Neurobiology(2016) 53(5):3113–3123. doi:10.1007/s12035-015-9211-5.
  • [29]Ulstein I, Bøhmer T. Normal Vitamin Levels and Nutritional Indices in Alzheimer’s Disease Patients with Mild Cognitive Impairment or Dementia with Normal BodyMass Indexes. Journal of Alzheimer's Disease(2016) 55(2):717–725. doi:10.3233/JAD-160393.
  • [30]Galesi LF, Leandro-Merhi VA, Oliveira MRM de. Association between indicators of dementia and nutritional status in institutionalised older people. International Journal of Older People Nursing(2013) 8(3):236–243. doi:10.1111/j.1748-3743.2012.00321.x.
  • [31]Lee CM, Woodward M, Batty GD, Beiser AS, Bell S, Berr C, et al. Association of anthropometry and weight change with risk of dementia and its major subtypes: Ameta‐analysis consisting 2.8 million adults with 57 294 cases of dementia. Obesity Reviews(2020) 21(4). doi:10.1111/obr.12989.
  • [32]Walrand S. Dietary supplement intake among the elderly. Current Opinion in Clinical Nutrition & Metabolic Care(2018) 21(6):465–470. doi:10.1097/MCO.0000000000000512.
  • [33]Mutt SJ, Jokelainen J, Sebert S, Auvinen J, Järvelin M-R, Keinänen-Kiukaanniemi S, et al. Vitamin D Status and Components of Metabolic Syndrome in Older Subjects from Northern Finland (Latitude 65°North). Nutrients(2019) 11(6):1229. doi:10.3390/nu11061229.
  • [34]Steingrimsdottir L. Relationship Between Serum Parathyroid Hormone Levels, Vitamin D Sufficiency, and Calcium Intake. JAMA(2005) 294(18):2336. doi:10.1001/jama.294.18.2336.
  • [35]NIH. Vitamin D Fact Sheet for Health Professionals. Washington, D.C: National Institutes of Health, 2021, Available at: https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/. [Accessed January 2022].
  • [36]Pettersen JA. Does high dose vitamin D supplementation enhancecognition? A randomized trial in healthy adults. Experimental Gerontology(2017) 90:90–97. doi:10.1016/j.exger.2017.01.019.
  • [37]Löppönen MK, Isoaho RE, Räihä IJ, Vahlberg TJ, Loikas SM, Takala TI, et al. Undiagnosed Diseases in Patients with Dementia –APotential Target Group for Intervention. Dementia and Geriatric Cognitive Disorders(2004) 18(3-4):321–329. doi:10.1159/000080126.
  • [38]Reitz C, Brickman AM, Luchsinger JA, Wu WE, Small SA, Tang M-X, et al. Frequency of Subclinical Heart Disease in Elderly Persons With Dementia. The American Journal of Geriatric Cardiology(2007) 16(3):183–188. doi:10.1111/j.1076-7460.2007.06511.x.
  • [39]Alzheimer’s and Dementia. 2021 Alzheimer’s Disease Facts And Figures. Alzheimer’s and Dementia. Chicago: Alzheimer’s Association 2021, Available at: https://www.alz.org/media/Documents/alzheimers-facts-and-figures.pdf. [Accessed January 2022].
  • [40]Ramdane S, Daoudi-Gueddah D. Mild Hypercholesterolemia, Normal Plasma Triglycerides, and Normal Glucose Levels Across Dementia Staging in Alzheimer’s Disease. American Journal of Alzheimer's Disease & Other Dementiasr(2011) 26(5):399–405. doi:10.1177/1533317511414552.
  • [41]Moretti R, Caruso P, Dal Ben M, Conti C, Gazzin S, Tiribelli C. Vitamin D, Homocysteine, and Folate in Subcortical Vascular Dementia and Alzheimer Dementia. Frontiers in Aging Neuroscience(2017) 9. doi:10.3389/fnagi.2017.00169.
  • [42]Yeşil Y, Kuyumcu ME, Kara Ö, Halaçlı B, Etgül S, Kızılarslanoğlu MC, et al. Vitamin D status and its association with gradual decline in cognitive function. Turkish Journal of Medica Sciences(2015) 45:1051–1057. doi:10.3906/sag-1405-11.
  • [43]Llewellyn DJ, Langa KM, Friedland RP, Lang IA. Serum albumin concentration and cognitive impairment. Current Alzheimer research(2010) 7(1):91–96. doi:10.2174/156720510790274392.
  • [44]Liu W, Cheon J, Thomas SA. Interventions on mealtime difficulties in older adults with dementia: A systematic review. International Journal of Nursing Studies(2014) 51(1):14–27. doi:10.1016/j.ijnurstu.2012.12.021.
  • [45]Gschwind YJ, Bischoff-Ferrari HA, Bridenbaugh SA, Härdi I, Kressig RW. Association between Serum Vitamin D Status and Functional Mobility in Memory Clinic Patients Aged 65 Years and Older. Gerontology(2014) 60(2):123–129. doi:10.1159/000355667.
  • [46]Feart C, Helmer C, Merle B, Herrmann FR, Annweiler C, Dartigues J-F, et al. Associations of lower vitamin D concentrations with cognitive decline and long‐term risk of dementia and Alzheimer's disease in older adults. Alzheimer's & Dementia(2017) 13(11):1207–1216. doi:10.1016/j.jalz.2017.03.003.
  • [47]Lee KS, Hong CH, Cheong H-K, Oh BH. Difference in nutritional risk between mild cognitive impairment group and normal cognitive function elderly group. Archives of Gerontology and Geriatrics(2009) 49(1):49–53.doi:10.1016/j.archger.2008.04.011.
  • [48]Camina MM, Barrera SO, Domínguez LR, Couceiro CM, Del Río Redondo MP. Presence of malnutrition and risk of malnutrition in institutionalized elderly with dementia according to the type and deterioration stage. Nutr.Hosp.(2012) 27:434–440. doi:10.1590/s0212-16112012000200013.
  • [49]Lee KS, Cheong H-K, Kim EA, Kim KR, Oh BH, Hong CH. Nutritional risk and cognitive impairment in the elderly. Archives of Gerontology and Geriatrics(2009) 48(1):95–99. doi:10.1016/j.archger.2007.11.001.
Toplam 49 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Mühendislik
Bölüm Research Articles
Yazarlar

Halime Uğur Bu kişi benim

Nihal Zekiye Erdem Bu kişi benim

Sümeyye Eker Bu kişi benim

Yayımlanma Tarihi 15 Temmuz 2022
Gönderilme Tarihi 30 Ocak 2022
Yayımlandığı Sayı Yıl 2022 Cilt: 6 Sayı: 1

Kaynak Göster

APA Uğur, H., Erdem, N. Z., & Eker, S. (2022). Clinical Characteristics and Geriatric Nutritional Risk Index Levels in Elderly People with Dementia Living in A Nursing Home. International Journal of Innovative Research and Reviews, 6(1), 35-41.