Obstetric and neonatal outcomes in pregnant women with fibromyalgia syndrome: A retrospective case-control study
Abstract
Objective: This study aims to evaluate obstetric and neonatal outcomes in pregnant women diagnosed with fibromyalgia syndrome (FMS) and to investigate the relationship between disease severity and complications.
Methods: This retrospective case-control study was conducted between August 2018 and August 2019. Sixty pregnant women diagnosed with FMS according to the 2016 ACR criteria were compared with 71 healthy pregnant women. FMS severity was assessed using the Widespread Pain Index (WPI) and Symptom Severity Scale (SSS). Obstetric complications, mode of delivery, and neonatal outcomes were recorded.
Results: The mean age of pregnant women with FMS was significantly higher (30.8±4.6 vs 27.9±5.1 years, p=0.002). The preterm birth rate was 26.7% in the FMS group and 7.0% in the control group (p<0.001). Premature rupture of membranes was more frequent in the FMS group (18.3% vs 5.6%, p=0.003). Birth weight was significantly lower in the FMS group (2,880±410 vs 3,210±390 g, p<0.001). The rate of Apgar 1 <7 was 66.7% in the FMS group and 4.2% in the control group (p<0.001). Neonatal intensive care unit (NICU) admission rate was higher in the FMS group (21.7% vs 4.2%, p=0.002). Complication rates increased as disease severity increased (p<0.05).
Conclusion: FMS is associated with serious obstetric and neonatal complications during pregnancy. Risks increase in parallel with disease severity. Pregnant women with FMS should be considered a high-risk group and managed with a multidisciplinary approach.
Keywords
References
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Details
Primary Language
English
Subjects
Obstetrics and Gynaecology, Physical Medicine and Rehabilitation
Journal Section
Research Article
Authors
Publication Date
April 16, 2026
Submission Date
November 7, 2025
Acceptance Date
January 27, 2026
Published in Issue
Year 2026 Volume: 17 Number: 57
APA
Ertürk Çelik, G. (2026). Obstetric and neonatal outcomes in pregnant women with fibromyalgia syndrome: A retrospective case-control study. Interdisciplinary Medical Journal, 17(57), 52-58. https://doi.org/10.17944/interdiscip.1819793
AMA
1.Ertürk Çelik G. Obstetric and neonatal outcomes in pregnant women with fibromyalgia syndrome: A retrospective case-control study. Interdiscip Med J. 2026;17(57):52-58. doi:10.17944/interdiscip.1819793
Chicago
Ertürk Çelik, Gülsemin. 2026. “Obstetric and Neonatal Outcomes in Pregnant Women With Fibromyalgia Syndrome: A Retrospective Case-Control Study”. Interdisciplinary Medical Journal 17 (57): 52-58. https://doi.org/10.17944/interdiscip.1819793.
EndNote
Ertürk Çelik G (April 1, 2026) Obstetric and neonatal outcomes in pregnant women with fibromyalgia syndrome: A retrospective case-control study. Interdisciplinary Medical Journal 17 57 52–58.
IEEE
[1]G. Ertürk Çelik, “Obstetric and neonatal outcomes in pregnant women with fibromyalgia syndrome: A retrospective case-control study”, Interdiscip Med J, vol. 17, no. 57, pp. 52–58, Apr. 2026, doi: 10.17944/interdiscip.1819793.
ISNAD
Ertürk Çelik, Gülsemin. “Obstetric and Neonatal Outcomes in Pregnant Women With Fibromyalgia Syndrome: A Retrospective Case-Control Study”. Interdisciplinary Medical Journal 17/57 (April 1, 2026): 52-58. https://doi.org/10.17944/interdiscip.1819793.
JAMA
1.Ertürk Çelik G. Obstetric and neonatal outcomes in pregnant women with fibromyalgia syndrome: A retrospective case-control study. Interdiscip Med J. 2026;17:52–58.
MLA
Ertürk Çelik, Gülsemin. “Obstetric and Neonatal Outcomes in Pregnant Women With Fibromyalgia Syndrome: A Retrospective Case-Control Study”. Interdisciplinary Medical Journal, vol. 17, no. 57, Apr. 2026, pp. 52-58, doi:10.17944/interdiscip.1819793.
Vancouver
1.Gülsemin Ertürk Çelik. Obstetric and neonatal outcomes in pregnant women with fibromyalgia syndrome: A retrospective case-control study. Interdiscip Med J. 2026 Apr. 1;17(57):52-8. doi:10.17944/interdiscip.1819793