Research Article
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Comparison of laparoscopic, abdominal, and vaginal hysterectomy methods in terms of clinical parameters

Year 2025, Volume: 16 Issue: 56, 162 - 167, 16.12.2025
https://doi.org/10.17944/interdiscip.1772824

Abstract

Objective: To compare the demographic characteristics, operative outcomes, laboratory findings, and complications among laparoscopic (n=254), abdominal (n=233), and vaginal (n=334) hysterectomy methods.
Methods: A retrospective analysis of 821 patients undergoing hysterectomy was conducted. Groups were compared for age, BMI (body mass index), operative time, intraoperative blood loss, postoperative hemoglobin drop (ΔHb), length of hospital stay, complication rates, wound infections, and presence of malignancy. Statistical significance was assessed with p < 0.05, and post-hoc analyses were adjusted accordingly.
Results: Mean age differed significantly among groups (p < 0.001), notably between laparoscopic (48 ± 6 years) and vaginal (50 ± 6 years) groups (adj. p < 0.001); BMI showed no significant difference (p = 0.089). Operative time was longest in the laparoscopic group (95 ± 14 min, p < 0.001, all post-hoc adj. p < 0.001). Blood loss was highest in the abdominal group (253 ± 67 cc) compared to laparoscopic (123 ± 40 cc) and vaginal (135 ± 37 cc) (p < 0.001, adj. p < 0.001). The postoperative hemoglobin decrease was greatest in the abdominal group (–2.73 ± 1.54 g/dL) versus laparoscopic (–1.58 ± 1.11 g/dL) and vaginal (–1.73 ± 0.97 g/dL) (p < 0.001, adj. p < 0.001). Hospital stay was shortest after vaginal hysterectomy (2.0 ± 0.5 days) and longest after abdominal (3.1 ± 0.8 days) (p < 0.001, adj. p < 0.001). Complication rate was highest in the abdominal group (16.3%), including wound infection (10.3%) (p < 0.001). Malignant pathology was more frequent
in the abdominal group (9.0%) compared to vaginal (3.3%) (p = 0.013).
Conclusion: Abdominal hysterectomy is associated with greater blood loss, larger hemoglobin drop, longer operative time and hospital stay, and higher complication and malignancy detection rates, whereas vaginal hysterectomy offers the shortest hospitalization. These findings underscore the importance of surgical method selection based on perioperative risk profiles.

References

  • Walsh CA, Walsh SR, Tang TY, Slack M. Total abdominal hysterectomy versus total laparoscopic hysterectomy for benign disease: a meta-analysis. Eur J Obstet Gynecol Reprod Biol. 2009 May;144(1):3-7. doi: 10.1016/j.ejogrb.2009.01.003.
  • Pickett CM, Seeratan DD, Mol BWJ, Nieboer TE, Johnson N, Bonestroo T, et al. Surgical approach to hysterectomy for benign gynaecological disease. Cochrane Database Syst Rev. 2023;29;8(8):CD003677. doi: 10.1002/14651858.CD003677.pub6.
  • Garry R, Fountain J, Mason S, Hawe J, Napp V, Abbott J, et al. The eVALuate study: two parallel randomised trials, one comparing laparoscopic with abdominal hysterectomy, the other comparing laparoscopic with vaginal hysterectomy. BMJ. 2004 Jan 17;328(7432):129. doi: 10.1136/bmj.37984.623889.F6. Epub 2004 Jan 7.
  • Committee Opinion No 701: Choosing the Route of Hysterectomy for Benign Disease. Obstet Gynecol. 2017;129(6):e155-e159. doi: 10.1097/AOG.0000000000002112.
  • Mäkinen J, Johansson J, Tomás C, Tomás E, Heinonen PK, Laatikainen T, et al. Morbidity of 10 110 hysterectomies by type of approach. Hum Reprod. 2001;16(7):1473-8. doi: 10.1093/humrep/16.7.1473.
  • Donnez O, Jadoul P, Squifflet J, Donnez J. A series of 3190 laparoscopic hysterectomies for benign disease from 1990 to 2006: evaluation of complications compared with vaginal and abdominal procedures. BJOG. 2009;116(4):492-500. doi: 10.1111/j.1471-0528.2008.01966.x.
  • Uccella S, Morosi C, Marconi N, Arrigo A, Gisone B, Casarin J, et al. Laparoscopic Versus Open Hysterectomy for Benign Disease in Uteri Weighing >1 kg: A Retrospective Analysis on 258 Patients. J Minim Invasive Gynecol. 2018;25(1):62-69. doi: 10.1016/j.jmig.2017.07.005.
  • Aarts JW, Nieboer TE, Johnson N, Tavender E, Garry R, Mol BW, et al. Surgical approach to hysterectomy for benign gynaecological disease. Cochrane Database Syst Rev. 2015 Aug 12;2015(8):CD003677. doi: 10.1002/14651858.CD003677.pub5. Update in: Cochrane Database Syst Rev. 2023 Aug 29;8:CD003677.
  • Neis F, Ayguen A, Sima RM, Solomayer EF, Juhasz-Boess I, Wagenpfeil G, et al. Access to Hysterectomy-What Is the Realistic Rate for Pure Vaginal Hysterectomy? A Single-Center Prospective Observational Study. J Clin Med. 2024 Oct 15;13(20):6130. doi: 10.3390/jcm13206130.
  • Mikhail E, Miladinovic B, Velanovich V, Finan MA, Hart S, Imudia AN. Association between obesity and the trends of routes of hysterectomy performed for benign indications. Obstet Gynecol. 2015 Apr;125(4):912-918. doi: 10.1097/AOG.0000000000000733.
  • Uwais A, Al-Abadleh A, Jahameh M, Satari A, Al-Hawamdeh Q, Haddadin S. A Comparison between Total Abdominal Hysterectomy versus Total Laparoscopic Hysterectomy. Gynecol Minim Invasive Ther. 2023 Dec 7;13(1):43-47. doi: 10.4103/gmit.gmit_72_23.
  • Brummer TH, Jalkanen J, Fraser J, Heikkinen AM, Kauko M, Mäkinen J, et al. FINHYST 2006--national prospective 1-year survey of 5,279 hysterectomies. Hum Reprod. 2009 Oct;24(10):2515-22. doi: 10.1093/humrep/dep229.
  • Johnson N, Barlow D, Lethaby A, Tavender E, Curr L, Garry R. Methods of hysterectomy: systematic review and meta-analysis of randomised controlled trials. BMJ. 2005 Jun 25;330(7506):1478. doi: 10.1136/ bmj.330.7506.1478.
  • Panda S, Das A, Das R, Sharma N, Shullai W, Jante V, et al. Analysis of Different Routes of Hysterectomy Based on a Prospective Algorithm and Their Complications in a Tertiary Care Institute. Minim Invasive Surg. 2022;15:2022:6034113. doi: 10.1155/2022/6034113.
  • Azadi A, Masoud AT, Ulibarri H, Arroyo A, Coriell C, Goetz S, et al. Vaginal Hysterectomy Compared With Laparoscopic Hysterectomy in Benign Gynecologic Conditions: A Systematic Review and Meta-analysis. Obstet Gynecol. 2023 Dec 1;142(6):1373-1394. doi: 10.1097/AOG.0000000000005434.
  • Antoun L, Middleton L, Smith P, Saridogan E, Cooper K, Brocklehurst P, et al. LAparoscopic Versus Abdominal hysterectomy (LAVA): protocol of a randomised controlled trial. BMJ Open. 2023;5:13(9):e070218. doi: 10.1136/bmjopen-2022-070218.
  • Agarwal M, Sinha S, Singh S, Haripriya H, Roy I. Surgical Morbidity of Laparoscopic Hysterectomy versus Abdominal Hysterectomy: A Retrospective Overview. Gynecol Minim Invasive Ther. 2023;10:12(3):161-165. doi: 10.4103/gmit.gmit_30_23.
  • Takahashi A, Uemura M, Kitazawa J, Nakata M, Hayashi Y. Laparoscopic Hysterectomy for Benign Pathology Does Not Yield More Perioperative Complications than Abdominal or Vaginal Hysterectomies: Our Experience in Introducing Laparoscopic Hysterectomy. Gynecol Minim Invasive Ther. 2020;15:9(4):215-219. doi:10.4103/GMIT.GMIT_116_19.
There are 18 citations in total.

Details

Primary Language English
Subjects Surgery (Other), Obstetrics and Gynaecology, Public Health (Other)
Journal Section Research Article
Authors

İlkan Kayar 0000-0001-6385-4730

Ferhat Çetin 0000-0002-8613-2711

Mustafa Çetin 0000-0003-2813-2163

Özer Birge 0000-0002-1939-3743

Submission Date August 28, 2025
Acceptance Date October 4, 2025
Publication Date December 16, 2025
Published in Issue Year 2025 Volume: 16 Issue: 56

Cite

Vancouver Kayar İ, Çetin F, Çetin M, Birge Ö. Comparison of laparoscopic, abdominal, and vaginal hysterectomy methods in terms of clinical parameters. Interdiscip Med J. 2025;16(56):162-7.