Assessment of the correlation between serum elafin concentrations and disease severity, erythrocyte sedimentation rate, and C-reactive protein levels in psoriasis patients

Yemliha Bozkurt; Cigdem Dogramaci

doi:10.17944/interdiscip.1882455

Assessment of the correlation between serum elafin concentrations and disease severity, erythrocyte sedimentation rate, and C-reactive protein levels in psoriasis patients

Abstract

Objective: This study was conducted to examine elafin levels between individuals with psoriasis and a healthy control group and to evaluate the relationship between elafin concentrations and disease severity, inflammatory markers, and lipid parameters. Method: The study sample included 40 psoriasis individuals in the Hatay Mustafa Kemal University Hospital Dermatology outpatient clinic and 40 healthy individuals matching the patient group. All subjects were characterized using demographic information, physical measurements, and biochemical markers. Results: It was found that elafin levels were significantly higher in psoriasis patients than in the healthy control group (p=0.028). Low-density lipoprotein (LDL) and total cholesterol levels increased, whereas high-density lipoprotein (HDL) levels decreased. Elafin levels positively correlate with LDL and total cholesterol. Conclusion: Elafin levels were higher in psoriasis patients, but this phenomenon was unrelated to disease severity or inflammatory markers.The correlation between elafin and lipid markers indicates a possible association between elafin and metabolic changes in psoriasis.

Keywords

Supporting Institution

Hatay Mustafa Kemal University, Medical Faculty Clinical / Human Research Ethics Committee

Ethical Statement

Ethical permission was obtained from the Hatay Mustafa Kemal University, Medical Faculty Clinical / Human Research Ethics Committee for this study with date 25th March, 2021 and number 08, and Helsinki Declaration rules were followed to conduct this study.

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Details

Primary Language

English

Subjects

Dermatology

Journal Section

Research Article

Authors

Yemliha Bozkurt ^*
0000-0001-9434-8355
Türkiye

Cigdem Dogramaci
0000-0003-4986-2149
Türkiye

Publication Date

August 23, 2026

Submission Date

February 5, 2026

Acceptance Date

July 25, 2026

Published in Issue

Year 2026 Volume: 17 Number: 58

DOI

https://doi.org/10.17944/interdiscip.1882455

IZ

https://izlik.org/JA38JP47BM

Cite

RIS / Bibtex

APA

Bozkurt, Y., & Dogramaci, C. (2026). Assessment of the correlation between serum elafin concentrations and disease severity, erythrocyte sedimentation rate, and C-reactive protein levels in psoriasis patients. Interdisciplinary Medical Journal, 17(58), 202-207. https://doi.org/10.17944/interdiscip.1882455

AMA

1.Bozkurt Y, Dogramaci C. Assessment of the correlation between serum elafin concentrations and disease severity, erythrocyte sedimentation rate, and C-reactive protein levels in psoriasis patients. Interdiscip Med J. 2026;17(58):202-207. doi:10.17944/interdiscip.1882455

Chicago

Bozkurt, Yemliha, and Cigdem Dogramaci. 2026. “Assessment of the Correlation Between Serum Elafin Concentrations and Disease Severity, Erythrocyte Sedimentation Rate, and C-Reactive Protein Levels in Psoriasis Patients”. Interdisciplinary Medical Journal 17 (58): 202-7. https://doi.org/10.17944/interdiscip.1882455.

EndNote

Bozkurt Y, Dogramaci C (August 1, 2026) Assessment of the correlation between serum elafin concentrations and disease severity, erythrocyte sedimentation rate, and C-reactive protein levels in psoriasis patients. Interdisciplinary Medical Journal 17 58 202–207.

IEEE

[1]Y. Bozkurt and C. Dogramaci, “Assessment of the correlation between serum elafin concentrations and disease severity, erythrocyte sedimentation rate, and C-reactive protein levels in psoriasis patients”, Interdiscip Med J, vol. 17, no. 58, pp. 202–207, Aug. 2026, doi: 10.17944/interdiscip.1882455.

ISNAD

Bozkurt, Yemliha - Dogramaci, Cigdem. “Assessment of the Correlation Between Serum Elafin Concentrations and Disease Severity, Erythrocyte Sedimentation Rate, and C-Reactive Protein Levels in Psoriasis Patients”. Interdisciplinary Medical Journal 17/58 (August 1, 2026): 202-207. https://doi.org/10.17944/interdiscip.1882455.

JAMA

1.Bozkurt Y, Dogramaci C. Assessment of the correlation between serum elafin concentrations and disease severity, erythrocyte sedimentation rate, and C-reactive protein levels in psoriasis patients. Interdiscip Med J. 2026;17:202–207.

MLA

Bozkurt, Yemliha, and Cigdem Dogramaci. “Assessment of the Correlation Between Serum Elafin Concentrations and Disease Severity, Erythrocyte Sedimentation Rate, and C-Reactive Protein Levels in Psoriasis Patients”. Interdisciplinary Medical Journal, vol. 17, no. 58, Aug. 2026, pp. 202-7, doi:10.17944/interdiscip.1882455.

Vancouver

1.Yemliha Bozkurt, Cigdem Dogramaci. Assessment of the correlation between serum elafin concentrations and disease severity, erythrocyte sedimentation rate, and C-reactive protein levels in psoriasis patients. Interdiscip Med J. 2026 Aug. 1;17(58):202-7. doi:10.17944/interdiscip.1882455