Postoperative outcomes and predictors of Hirschsprung-associated enterocolitis after transanal endorectal pull-through: a single-centre retrospective cohort of 71 patients

Ozkan Okur; Bahoz Biçer; Mehmet Can; Arzu Şencan

doi:10.17944/interdiscip.1958978

Postoperative outcomes and predictors of Hirschsprung-associated enterocolitis after transanal endorectal pull-through: a single-centre retrospective cohort of 71 patients

Abstract

Objective: To describe the perioperative and longer-term outcomes of a single-center cohort undergoing transanal endorectal pull-through (TEPT) for Hirschsprung disease (HSCR), and to identify independent predictors of postoperative Hirschsprung-associated enterocolitis (HAEC). Method: A retrospective review of 71 patients undergoing TEPT at a single institution was performed. Postoperative HAEC was analysed under two definitions: early postoperative HAEC (within the first postoperative year) and any postoperative HAEC during follow-up. Anastomotic stricture was reported under a broad clinical definition and a strict definition restricted to cases requiring operative revision. Univariate and multivariable logistic regression with four a priori covariates (age at surgery, preoperative HAEC, long/total-segment aganglionosis, one-stage operation) was used to identify independent predictors of postoperative HAEC. Results: Median age at definitive surgery was 2.0 months and median follow-up was 60 months. Anastomotic stricture occurred in 35.2% under the broad definition and 9.9% under the strict definition. Early postoperative HAEC was documented in 12.7% and any postoperative HAEC in 22.5%. Preoperative HAEC was an independent predictor of both early and any postoperative HAEC. One-stage pull-through was independently protective against any postoperative HAEC. Long- or total-segment aganglionosis was associated with a higher broad-definition stricture rate (62.5% vs 27.3%, p=0.016) but not the strict definition (12.5% vs 9.1%, p=0.651). Conclusion: Preoperative HAEC and one-stage operation are independently associated with postoperative HAEC after TEPT. Reporting anastomotic stricture under both broad and strict definitions improves comparability with other single-center series.

Keywords

Supporting Institution

none

Ethical Statement

Ethical approval was obtained from the Dr. Behçet Uz Children’s Hospital Ethical Committee with protocol number GOA-363 and approval date 21.05.2026. The study was conducted in accordance with the principles of the Declaration of Helsinki. The requirement for individual informed consent was waived due to the retrospective design and the use of de-identified data.

Thanks

none

References

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Details

Primary Language

English

Subjects

Surgery (Other), Paediatrics (Other)

Journal Section

Research Article

Authors

Ozkan Okur ^*
0000-0002-3928-4659
Türkiye

Bahoz Biçer
0009-0003-9986-8909
Türkiye

Mehmet Can
0000-0002-4263-0911
Türkiye

Arzu Şencan
0000-0003-4499-7984
Türkiye

Publication Date

August 23, 2026

Submission Date

May 26, 2026

Acceptance Date

July 7, 2026

Published in Issue

Year 2026 Volume: 17 Number: 58

DOI

https://doi.org/10.17944/interdiscip.1958978

IZ

https://izlik.org/JA36LT33YD

Cite

RIS / Bibtex

APA

Okur, O., Biçer, B., Can, M., & Şencan, A. (2026). Postoperative outcomes and predictors of Hirschsprung-associated enterocolitis after transanal endorectal pull-through: a single-centre retrospective cohort of 71 patients. Interdisciplinary Medical Journal, 17(58), 185-194. https://doi.org/10.17944/interdiscip.1958978

AMA

1.Okur O, Biçer B, Can M, Şencan A. Postoperative outcomes and predictors of Hirschsprung-associated enterocolitis after transanal endorectal pull-through: a single-centre retrospective cohort of 71 patients. Interdiscip Med J. 2026;17(58):185-194. doi:10.17944/interdiscip.1958978

Chicago

Okur, Ozkan, Bahoz Biçer, Mehmet Can, and Arzu Şencan. 2026. “Postoperative Outcomes and Predictors of Hirschsprung-Associated Enterocolitis After Transanal Endorectal Pull-Through: A Single-Centre Retrospective Cohort of 71 Patients”. Interdisciplinary Medical Journal 17 (58): 185-94. https://doi.org/10.17944/interdiscip.1958978.

EndNote

Okur O, Biçer B, Can M, Şencan A (August 1, 2026) Postoperative outcomes and predictors of Hirschsprung-associated enterocolitis after transanal endorectal pull-through: a single-centre retrospective cohort of 71 patients. Interdisciplinary Medical Journal 17 58 185–194.

IEEE

[1]O. Okur, B. Biçer, M. Can, and A. Şencan, “Postoperative outcomes and predictors of Hirschsprung-associated enterocolitis after transanal endorectal pull-through: a single-centre retrospective cohort of 71 patients”, Interdiscip Med J, vol. 17, no. 58, pp. 185–194, Aug. 2026, doi: 10.17944/interdiscip.1958978.

ISNAD

Okur, Ozkan - Biçer, Bahoz - Can, Mehmet - Şencan, Arzu. “Postoperative Outcomes and Predictors of Hirschsprung-Associated Enterocolitis After Transanal Endorectal Pull-Through: A Single-Centre Retrospective Cohort of 71 Patients”. Interdisciplinary Medical Journal 17/58 (August 1, 2026): 185-194. https://doi.org/10.17944/interdiscip.1958978.

JAMA

1.Okur O, Biçer B, Can M, Şencan A. Postoperative outcomes and predictors of Hirschsprung-associated enterocolitis after transanal endorectal pull-through: a single-centre retrospective cohort of 71 patients. Interdiscip Med J. 2026;17:185–194.

MLA

Okur, Ozkan, et al. “Postoperative Outcomes and Predictors of Hirschsprung-Associated Enterocolitis After Transanal Endorectal Pull-Through: A Single-Centre Retrospective Cohort of 71 Patients”. Interdisciplinary Medical Journal, vol. 17, no. 58, Aug. 2026, pp. 185-94, doi:10.17944/interdiscip.1958978.

Vancouver

1.Ozkan Okur, Bahoz Biçer, Mehmet Can, Arzu Şencan. Postoperative outcomes and predictors of Hirschsprung-associated enterocolitis after transanal endorectal pull-through: a single-centre retrospective cohort of 71 patients. Interdiscip Med J. 2026 Aug. 1;17(58):185-94. doi:10.17944/interdiscip.1958978