Araştırma Makalesi
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Yıl 2018, Cilt: 48 Sayı: 3, 89 - 99, 01.12.2018

Öz

Kaynakça

  • Ahmad A, Husain A, Mujeeb M, Khan SA, Najmi AK, Siddique NA, Damanhouri ZA, Anwar F. (2013). A review on therapeutic potential of Nigella sativa: A miracle herb. Asian Pac J Trop Biomed 3(5): 337-352. Ahmad I, Tripathi J, Manik S, Umar L, JR. (2013). Preliminary Phytochemical Studies of the Miracle Herb of the Century, Nigella sativa L. (Black Seed). Indo Am J Pharm Res 3(4): 3000-3007. Ahmad S, Beg ZH. (2014). Mitigating role of thymoquinone rich fractions from Nigella sativa oil and its constituents, thymoquinone and limonene on lipidemic-oxidative injury in rats. Springerplus 3(1): 316. Alobaedi OH, Talib WH, Basheti IA. (2017). Antitumor effect of thymoquinone combined with resveratrol on mice transplanted with breast cancer. Asian Pac J Trop Biomed 10(4): 400-408. Andzouana M, Mombouli JB. (2011). Chemical composition and phytochemical screening of the leaves of Hymenocardiaulmoides and Vitexferruginea. Pak J Nutr 10(12): 1183-1189. Arici M, Sagdic O, Gecgel U. (2005). Antibacterial effect of Turkish black cumin (Nigella sativa L.) oils. Grasas y Aceites 56(4): 259-262. Aumeeruddy MZ, Zengin G, Mahomoodally MF. (2017). A review of the traditional and modern uses of Salvadora persica L.(Miswak): Toothbrush tree of Prophet Muhammad. J Ethnopharmacol 213: 409-444. Baharetha HM, Nassar ZD, Aisha AF, Ahamed MBK, Al-Suede FSR, Kadir MOA, Ismail Z, Majid AMSA. (2013). Proapoptotic and antimetastatic properties of supercritical CO2 extract of Nigella sativa Linn. against breast cancer cells. J Med Food 16(12): 1121-1130. Bieth J, Spiess B, Wermuth CG. (1974). The synthesis and analytical use of a highly sensitive and convenient substrate of elastase. Biochem Med 11(4): 350-357. Boussaid A, Chouaibi M, Rezig L, Hellal R, Donsì F, Ferrari G, Hamdi S. (2014). Physicochemical and bioactive properties of six honey samples from various floral origins from Tunisia. Arab J Chem 11: 265-274. Burits M, Bucar F. (2000). Antioxidant activity of Nigella sativa essential oil. Phytother Res 14(5): 323-328. Cakir M, Sakalar C, Sezen S, Aksu H, Kurt B, Canatan H. (2016). Thymoquinone confers higher cytotoxicity against triple negative breast cancer compared to estrogen receptor positive breast cancer through modulation of TNF receptor superfamily genes and P65 activity. Eur J Cancer 61: S138-S139. Cheikh-Rouhou S, Besbes S, Hentati B, Blecker C, Deroanne C, Attia H. (2007). Nigella sativa L.: Chemical composition and physicochemical characteristics of lipid fraction. Food Chem 101(2): 673-681. CLSI (2015). Performance standards for antimicrobial susceptibility testing; Twenty-second informational supplement. CLSI document M100-S22. Wayne, PA: Clinical and Laboratory Standards Institute. Eid AM, Elmarzugi NA, Abu Ayyash LM, Sawafta MN, Daana HI. (2017). A Review on the Cosmeceutical and External Applications of Nigella sativa. J Trop Med doi.org/10.1155/2017/7092514. Elkady AI. (2012). Crude extract of Nigella sativa inhibits proliferation and induces apoptosis in human cervical carcinoma HeLa cells. African Journal of Biotechnology, 11(64): 12710-12720. Farah IO. (2005). Assessment of cellular responses to oxidative stress using MCF-7 breast cancer cells, black seed (N. Sativa L.) extracts and H2O2. Int J Environ Res Public Health 2(3): 411-419. Feroz S, Uddin G. (2016). Phytochemical Analysis, Antimicrobial and Antioxidant Study of Nigella sativa Int J Pharm Chem 2(2): 36-43. Gilani AUH, Jabeen Q, Khan MAU. (2004). A review of medicinal uses and pharmacological activities of Nigella sativa. Pak J Biol Sci 7(4): 441-445. Goga A, Hasic S, Becirovic S, Cavar S. (2012). Phenolic compounds and antioxidant Activity of extracts of Nigella sativa L. Bull Chemists Technol Bosnia Herzegovina 39: 15-19.

Biological, phytochemical, and physico-chemical properties of two commercial Nigella sativa seed oils: A comparative analysis

Yıl 2018, Cilt: 48 Sayı: 3, 89 - 99, 01.12.2018

Öz

This study was designed to evaluate and
correlate the biological, phytochemical, and physicochemical properties of two
NSS (Nigella sativa seed) oils (N1 and N2). The biological activity was evaluated
in terms of antibacterial, antioxidant (nitric oxide scavenging), antielastase,
antityrosinase, antimelanogenic, and anticancer activity. Physicochemical
properties including colour, total soluble solids (TSS), and density were also
investigated. N2 exhibited higher antibacterial, NO scavenging, extracellular
antimelanogenic, and anticancer activity against the HeLa cell line compared to
N1, which showed higher antityrosinase activity. TPC (total phenolic content)
and TFC (total flavonoid content) of N1 were significantly higher than N2 while
TTC (total tannin content) was higher in N2. In fact, TTC was strongly
correlated (R=1.000) with the antioxidant, extracellular antimelanogenic, and
HeLa cell inhibitory activity. To conclude, NSS oil may be considered as a
complementary and alternative therapy in the management of infectious and
chronic diseases but warrants further in vivo pharmacological validation and
toxicological analysis.

Kaynakça

  • Ahmad A, Husain A, Mujeeb M, Khan SA, Najmi AK, Siddique NA, Damanhouri ZA, Anwar F. (2013). A review on therapeutic potential of Nigella sativa: A miracle herb. Asian Pac J Trop Biomed 3(5): 337-352. Ahmad I, Tripathi J, Manik S, Umar L, JR. (2013). Preliminary Phytochemical Studies of the Miracle Herb of the Century, Nigella sativa L. (Black Seed). Indo Am J Pharm Res 3(4): 3000-3007. Ahmad S, Beg ZH. (2014). Mitigating role of thymoquinone rich fractions from Nigella sativa oil and its constituents, thymoquinone and limonene on lipidemic-oxidative injury in rats. Springerplus 3(1): 316. Alobaedi OH, Talib WH, Basheti IA. (2017). Antitumor effect of thymoquinone combined with resveratrol on mice transplanted with breast cancer. Asian Pac J Trop Biomed 10(4): 400-408. Andzouana M, Mombouli JB. (2011). Chemical composition and phytochemical screening of the leaves of Hymenocardiaulmoides and Vitexferruginea. Pak J Nutr 10(12): 1183-1189. Arici M, Sagdic O, Gecgel U. (2005). Antibacterial effect of Turkish black cumin (Nigella sativa L.) oils. Grasas y Aceites 56(4): 259-262. Aumeeruddy MZ, Zengin G, Mahomoodally MF. (2017). A review of the traditional and modern uses of Salvadora persica L.(Miswak): Toothbrush tree of Prophet Muhammad. J Ethnopharmacol 213: 409-444. Baharetha HM, Nassar ZD, Aisha AF, Ahamed MBK, Al-Suede FSR, Kadir MOA, Ismail Z, Majid AMSA. (2013). Proapoptotic and antimetastatic properties of supercritical CO2 extract of Nigella sativa Linn. against breast cancer cells. J Med Food 16(12): 1121-1130. Bieth J, Spiess B, Wermuth CG. (1974). The synthesis and analytical use of a highly sensitive and convenient substrate of elastase. Biochem Med 11(4): 350-357. Boussaid A, Chouaibi M, Rezig L, Hellal R, Donsì F, Ferrari G, Hamdi S. (2014). Physicochemical and bioactive properties of six honey samples from various floral origins from Tunisia. Arab J Chem 11: 265-274. Burits M, Bucar F. (2000). Antioxidant activity of Nigella sativa essential oil. Phytother Res 14(5): 323-328. Cakir M, Sakalar C, Sezen S, Aksu H, Kurt B, Canatan H. (2016). Thymoquinone confers higher cytotoxicity against triple negative breast cancer compared to estrogen receptor positive breast cancer through modulation of TNF receptor superfamily genes and P65 activity. Eur J Cancer 61: S138-S139. Cheikh-Rouhou S, Besbes S, Hentati B, Blecker C, Deroanne C, Attia H. (2007). Nigella sativa L.: Chemical composition and physicochemical characteristics of lipid fraction. Food Chem 101(2): 673-681. CLSI (2015). Performance standards for antimicrobial susceptibility testing; Twenty-second informational supplement. CLSI document M100-S22. Wayne, PA: Clinical and Laboratory Standards Institute. Eid AM, Elmarzugi NA, Abu Ayyash LM, Sawafta MN, Daana HI. (2017). A Review on the Cosmeceutical and External Applications of Nigella sativa. J Trop Med doi.org/10.1155/2017/7092514. Elkady AI. (2012). Crude extract of Nigella sativa inhibits proliferation and induces apoptosis in human cervical carcinoma HeLa cells. African Journal of Biotechnology, 11(64): 12710-12720. Farah IO. (2005). Assessment of cellular responses to oxidative stress using MCF-7 breast cancer cells, black seed (N. Sativa L.) extracts and H2O2. Int J Environ Res Public Health 2(3): 411-419. Feroz S, Uddin G. (2016). Phytochemical Analysis, Antimicrobial and Antioxidant Study of Nigella sativa Int J Pharm Chem 2(2): 36-43. Gilani AUH, Jabeen Q, Khan MAU. (2004). A review of medicinal uses and pharmacological activities of Nigella sativa. Pak J Biol Sci 7(4): 441-445. Goga A, Hasic S, Becirovic S, Cavar S. (2012). Phenolic compounds and antioxidant Activity of extracts of Nigella sativa L. Bull Chemists Technol Bosnia Herzegovina 39: 15-19.
Toplam 1 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Kurumları Yönetimi
Bölüm Original Article
Yazarlar

Muhammad Zakariyyah Aumeeruddy Bu kişi benim

Zaahira Aumeeruddy-elalfi Bu kişi benim

Hudaa Neetoo Bu kişi benim

Gökhan Zengin Bu kişi benim

Bianca Fibrich Bu kişi benim

Sunelle Rademan Bu kişi benim

Analike Blom Van Staden Bu kişi benim

Karina Szuman Bu kişi benim

İsa Anina Lambrechts Bu kişi benim

Namrita Lall Bu kişi benim

Mohamad Fawzi Mahomoodally Bu kişi benim

Yayımlanma Tarihi 1 Aralık 2018
Gönderilme Tarihi 13 Eylül 2018
Yayımlandığı Sayı Yıl 2018 Cilt: 48 Sayı: 3

Kaynak Göster

APA Aumeeruddy, M. Z., Aumeeruddy-elalfi, Z., Neetoo, H., Zengin, G., vd. (2018). Biological, phytochemical, and physico-chemical properties of two commercial Nigella sativa seed oils: A comparative analysis. İstanbul Journal of Pharmacy, 48(3), 89-99.
AMA Aumeeruddy MZ, Aumeeruddy-elalfi Z, Neetoo H, Zengin G, Fibrich B, Rademan S, Staden ABV, Szuman K, Lambrechts İA, Lall N, Mahomoodally MF. Biological, phytochemical, and physico-chemical properties of two commercial Nigella sativa seed oils: A comparative analysis. iujp. Aralık 2018;48(3):89-99.
Chicago Aumeeruddy, Muhammad Zakariyyah, Zaahira Aumeeruddy-elalfi, Hudaa Neetoo, Gökhan Zengin, Bianca Fibrich, Sunelle Rademan, Analike Blom Van Staden, Karina Szuman, İsa Anina Lambrechts, Namrita Lall, ve Mohamad Fawzi Mahomoodally. “Biological, Phytochemical, and Physico-Chemical Properties of Two Commercial Nigella Sativa Seed Oils: A Comparative Analysis”. İstanbul Journal of Pharmacy 48, sy. 3 (Aralık 2018): 89-99.
EndNote Aumeeruddy MZ, Aumeeruddy-elalfi Z, Neetoo H, Zengin G, Fibrich B, Rademan S, Staden ABV, Szuman K, Lambrechts İA, Lall N, Mahomoodally MF (01 Aralık 2018) Biological, phytochemical, and physico-chemical properties of two commercial Nigella sativa seed oils: A comparative analysis. İstanbul Journal of Pharmacy 48 3 89–99.
IEEE M. Z. Aumeeruddy, “Biological, phytochemical, and physico-chemical properties of two commercial Nigella sativa seed oils: A comparative analysis”, iujp, c. 48, sy. 3, ss. 89–99, 2018.
ISNAD Aumeeruddy, Muhammad Zakariyyah vd. “Biological, Phytochemical, and Physico-Chemical Properties of Two Commercial Nigella Sativa Seed Oils: A Comparative Analysis”. İstanbul Journal of Pharmacy 48/3 (Aralık 2018), 89-99.
JAMA Aumeeruddy MZ, Aumeeruddy-elalfi Z, Neetoo H, Zengin G, Fibrich B, Rademan S, Staden ABV, Szuman K, Lambrechts İA, Lall N, Mahomoodally MF. Biological, phytochemical, and physico-chemical properties of two commercial Nigella sativa seed oils: A comparative analysis. iujp. 2018;48:89–99.
MLA Aumeeruddy, Muhammad Zakariyyah vd. “Biological, Phytochemical, and Physico-Chemical Properties of Two Commercial Nigella Sativa Seed Oils: A Comparative Analysis”. İstanbul Journal of Pharmacy, c. 48, sy. 3, 2018, ss. 89-99.
Vancouver Aumeeruddy MZ, Aumeeruddy-elalfi Z, Neetoo H, Zengin G, Fibrich B, Rademan S, Staden ABV, Szuman K, Lambrechts İA, Lall N, Mahomoodally MF. Biological, phytochemical, and physico-chemical properties of two commercial Nigella sativa seed oils: A comparative analysis. iujp. 2018;48(3):89-9.