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The epidemiology of tympanosclerosis in chronic otitis media patients in the Kars region of Turkey: The role of computerized temporal tomography in diagnosis of tympanosclerosis

Yıl 2019, Cilt: 11 Sayı: 2, 825 - 834, 23.06.2019
https://doi.org/10.37212/jcnos.683514

Öz

The aim of this study was to evaluate tympanosclerosis patients operated with tympanoplasty in terms of patient profile, clinical characteristics, diagnostic role of preoperative computed tomography (CT) and postoperative graft and hearing outcome. The patients operated with tympanoplasty due to tympanosclerosis were included in this study. Data on patient demographics, type of otitis media, preoperative findings, characteristics of tympanosclerosis, preoperative temporal bone CT findings and preoperative and post-operative audiological assessment were recorded in each patient. Postoperative hearing outcome (pure tone averages, air-bone gap) and graft survival rates were also recorded. Most of patients with operated tympanosclerosis were females (75.9%) and in the 41-60 year (37.0%) age group. CSOM (81.5%) was the most common diagnosis. Tympanosclerosis was open type in 94.0% and located in posterioinferior tympanic membrane in 35.2% of patients and in epitympanum of middle ear in 53.7% of patients with involvement of malleus and incus in most of cases. Loss of mastoid air and volume (94.4%) and high-density areas in middle ear and around ossicles (88.9%) were the leading findings on pre-operative temporal bone CT. Overall graft survival rate was 75.5%, and higher with cartilage than temporal fascia grafts. A significant improvement was noted in pure tone average and air-bone gap (p=0.000). Preoperative temporal bone CT findings seem to offer a potential pre-surgical guide for surgeons operating tympanosclerosis. Tympanoplasty was associated with favorable graft outcome, particularly for cartilage rather than temporal fascia grafts and improved postoperative hearing outcome in terms of pure tone averages and air-bone gap, regardless of the graft type.

Kaynakça

  • Ağrı İ, Ağrı AE, Özdemir D, Özgür A. CAPE and Tympanosclerosis. Polyphenols: Mechanisms of Action in Human Health and Disease (Second Edition). 2018;(31): 421-430. Aslan H, Katilmiş H, Oztürkcan S, Ilknur AE, Başoğlu S.Tympanosclerosis and our surgical results. Eur Arch Otorhinolaryngol. 2010;267(5):673-7. Bayazit YA, Ozer E, Kara C, Gokpinar S, Kanlikama M, Mumbuc S. An analysis of the single- stage tympanoplasty with over-underlay grafting in tympanosclerosis. Otol Neurotol. 2004;25(3):211- 4. Boyraz E, Erdogan N, Boyraz I, Kazikdas C, Etit D, Uluc E. [The importance of computed tomography examination of temporal bone in detecting tympanosclerosis]. Kulak Burun Bogaz Ihtis Derg. 2009;19(6):294-8. Cabra J, Monux A. Efficacy of cartilage palisade tympanoplasty: randomized controlled trial. Otol Neurotol 2010;31(4):589-95. Dornelles C, Schmidt Rosito LP, Meurer L, da Costa SS, Argenta A, Alves SL. Hystology findings' correlation between the ossicular chain in the transoperative and cholesteatomas. Braz J Otorhinolaryngol. 2007;73(6):738-43. Dornhoffer J. Cartilage tympanoplasty: indications, techniques, and outcomes in a 1,000- patient series. Laryngoscope. 2003;113(11):1844-56. Dornhoffer JL. Surgical management of the atelectatic ear. Am J Otol. 2000;21(3):315-21. Forseni M, Bagger-Sjoback D, Hultcrantz M. A study of inflammatory mediators in the human tympanosclerotic middle ear. Arch Otolaryngol Head Neck Surg. 2001;127(5):559-64. Garov EV, Sidorina NG, Zagorskaya EE, Sudarev PA, Meparishvili AS.[The prevalence of tympanosclerosis and the effectiveness of its surgical treatment]. Vestn Otorinolaringol. 2017;82(2):4-10. Gibb AG, Pang YT. Current considerations in the etiology and diagnosis of tympanosclerosis. Eur Arch Otorhinolaryngol. 1994;251(8):439-51. Giddings NA, House JW. Tympanosclerosis of the stapes: hearing results for various surgical treatments. Otolaryngol Head Neck Surg. 1992;107(5):644-50. Glasscock ME, Jackson CG, Nissen AJ, Schwaber MK. Postauricular undersurface tympanic membrane grafting: a follow-up report. Laryngoscope. 1982;92(7):718-27. Gurr A, Hildmann H, Stark T, Dazert S. [Treatment of tympanosclerosis]. HNO. 2008;56(6):651-7. Hasham A, Anazy F, Zakzouk S, Banjar A. Tympanosclerosis: review of literature and incidence among patients with middle-ear infection. J Laryngol Otol 1999;113(12):1076-80. Ho KY, Tsai SM, Chai CY, Wang HM. Clinical analysis of intratympanic tympanosclerosis: etiology, ossicular chain findings, and hearing results of surgery. Acta Otolaryngol. 2010;130(3):370- 4. Jalali MM, Motasaddi M, Kouhi A, Dabiri S, Soleimani R. Comparison of cartilage with temporalis fascia tympanoplasty: A meta-analysis of comparative studies. Laryngoscope. 2017;127(9):2139-48. Kalcioglu MT, Cokkeser Y, Kizilay A, Ozturan O. Follow-up of 366 ears after tympanostomy tube insertion: why is it draining? Otolaryngol Head Neck Surg . 2003;128(4):560-4. Karlidag T, Ilhan N, Kaygusuz I, Keles E, Yalcin S. Comparison of free radicals and antioxidant enzymes in chronic otitis media with and without tympanosclerosis. Laryngoscope 2004;114(1):85-9. Kucuktag Z, Satar B, Yetiser S, Hidir Y, Gunhan O. Immunohistochemical investigation of inducible nitric oxide synthase, osteopontin, and calcium-sensing receptor in a myringosclerosis/tympanosclerosis model. Otol Neurotol. 2014;35(1):e15-23. Magliocca KR, Vivas EX, Griffith CC. Idiopathic, Infectious and Reactive Lesions of the Ear and Temporal Bone. Head Neck Pathol. 2018;12(3):328-349. Mattsson C, Marklund SL, Hellström S. Application of oxygen free radical scavengers to diminish the occurrence of myringosclerosis. Ann Otol Rhinol Laryngol.1997;106:513-8. Milewski C.Composite graft tympanoplasty in the treatment of ears with advanced middle ear pathology. Laryngoscope. 1993 ;103(12):1352-6. Mutlu F, Iseri M, Erdogan S, Ozturk M, Sari F. An Analysis of Surgical Treatment Results of Patients With Tympanosclerosis. J Craniofac Surg. 2015;26(8):2393-5. Pal I, Sengupta A. Clinicopathological and audiological study of tympanosclerrosis. Indian Journal of Otolaryngology and Head and Neck Surgery. 2005;57(3):235-9. Stankovic MD. Hearing results of surgery for tympanosclerosis. Eur Arch Otorhinolaryngol. 2009;266(5):635-40. Swartz JD, Goodman RS, Russell KB, Marlowe FI, Wolfson RJ. High-Resolution Computed-Tomography of the Middle-Ear and Mastoid .2. Tubotympanic Disease. [Article in English] Radiology. 1983;148(2):455-9. Tos M, Lau T, Arndal H, Plate S. Tympanosclerosis of the middle ear: late results of surgical treatment. J Laryngol Otol 1990;104(9):685-9. Walshe P, McConn Walsh R, Brennan P, Walsh M. The role of computerized tomography in the preoperative assessment of chronic suppurative otitis media. Clin Otolaryngol Allied Sci. 2002;27(2):95-7. Wu Y, Yin S, Zhu H, Zhang S. [Tympanosclerosis incidence among patients with chronic suppurative otitis media]. Lin Chuang Er Bi Yan Hou Ke Za Zhi. 2006;20(22):1016-7. Yuen AP, Ho WK, Hui Y, Wei WI, Au DK. Correlation of pure tone audiogram results and hearing benefit of tympanoplasty for chronic suppurative otitis media. Ann Otol Rhinol Laryngol. 2000;109(4):381-384.
Yıl 2019, Cilt: 11 Sayı: 2, 825 - 834, 23.06.2019
https://doi.org/10.37212/jcnos.683514

Öz

Kaynakça

  • Ağrı İ, Ağrı AE, Özdemir D, Özgür A. CAPE and Tympanosclerosis. Polyphenols: Mechanisms of Action in Human Health and Disease (Second Edition). 2018;(31): 421-430. Aslan H, Katilmiş H, Oztürkcan S, Ilknur AE, Başoğlu S.Tympanosclerosis and our surgical results. Eur Arch Otorhinolaryngol. 2010;267(5):673-7. Bayazit YA, Ozer E, Kara C, Gokpinar S, Kanlikama M, Mumbuc S. An analysis of the single- stage tympanoplasty with over-underlay grafting in tympanosclerosis. Otol Neurotol. 2004;25(3):211- 4. Boyraz E, Erdogan N, Boyraz I, Kazikdas C, Etit D, Uluc E. [The importance of computed tomography examination of temporal bone in detecting tympanosclerosis]. Kulak Burun Bogaz Ihtis Derg. 2009;19(6):294-8. Cabra J, Monux A. Efficacy of cartilage palisade tympanoplasty: randomized controlled trial. Otol Neurotol 2010;31(4):589-95. Dornelles C, Schmidt Rosito LP, Meurer L, da Costa SS, Argenta A, Alves SL. Hystology findings' correlation between the ossicular chain in the transoperative and cholesteatomas. Braz J Otorhinolaryngol. 2007;73(6):738-43. Dornhoffer J. Cartilage tympanoplasty: indications, techniques, and outcomes in a 1,000- patient series. Laryngoscope. 2003;113(11):1844-56. Dornhoffer JL. Surgical management of the atelectatic ear. Am J Otol. 2000;21(3):315-21. Forseni M, Bagger-Sjoback D, Hultcrantz M. A study of inflammatory mediators in the human tympanosclerotic middle ear. Arch Otolaryngol Head Neck Surg. 2001;127(5):559-64. Garov EV, Sidorina NG, Zagorskaya EE, Sudarev PA, Meparishvili AS.[The prevalence of tympanosclerosis and the effectiveness of its surgical treatment]. Vestn Otorinolaringol. 2017;82(2):4-10. Gibb AG, Pang YT. Current considerations in the etiology and diagnosis of tympanosclerosis. Eur Arch Otorhinolaryngol. 1994;251(8):439-51. Giddings NA, House JW. Tympanosclerosis of the stapes: hearing results for various surgical treatments. Otolaryngol Head Neck Surg. 1992;107(5):644-50. Glasscock ME, Jackson CG, Nissen AJ, Schwaber MK. Postauricular undersurface tympanic membrane grafting: a follow-up report. Laryngoscope. 1982;92(7):718-27. Gurr A, Hildmann H, Stark T, Dazert S. [Treatment of tympanosclerosis]. HNO. 2008;56(6):651-7. Hasham A, Anazy F, Zakzouk S, Banjar A. Tympanosclerosis: review of literature and incidence among patients with middle-ear infection. J Laryngol Otol 1999;113(12):1076-80. Ho KY, Tsai SM, Chai CY, Wang HM. Clinical analysis of intratympanic tympanosclerosis: etiology, ossicular chain findings, and hearing results of surgery. Acta Otolaryngol. 2010;130(3):370- 4. Jalali MM, Motasaddi M, Kouhi A, Dabiri S, Soleimani R. Comparison of cartilage with temporalis fascia tympanoplasty: A meta-analysis of comparative studies. Laryngoscope. 2017;127(9):2139-48. Kalcioglu MT, Cokkeser Y, Kizilay A, Ozturan O. Follow-up of 366 ears after tympanostomy tube insertion: why is it draining? Otolaryngol Head Neck Surg . 2003;128(4):560-4. Karlidag T, Ilhan N, Kaygusuz I, Keles E, Yalcin S. Comparison of free radicals and antioxidant enzymes in chronic otitis media with and without tympanosclerosis. Laryngoscope 2004;114(1):85-9. Kucuktag Z, Satar B, Yetiser S, Hidir Y, Gunhan O. Immunohistochemical investigation of inducible nitric oxide synthase, osteopontin, and calcium-sensing receptor in a myringosclerosis/tympanosclerosis model. Otol Neurotol. 2014;35(1):e15-23. Magliocca KR, Vivas EX, Griffith CC. Idiopathic, Infectious and Reactive Lesions of the Ear and Temporal Bone. Head Neck Pathol. 2018;12(3):328-349. Mattsson C, Marklund SL, Hellström S. Application of oxygen free radical scavengers to diminish the occurrence of myringosclerosis. Ann Otol Rhinol Laryngol.1997;106:513-8. Milewski C.Composite graft tympanoplasty in the treatment of ears with advanced middle ear pathology. Laryngoscope. 1993 ;103(12):1352-6. Mutlu F, Iseri M, Erdogan S, Ozturk M, Sari F. An Analysis of Surgical Treatment Results of Patients With Tympanosclerosis. J Craniofac Surg. 2015;26(8):2393-5. Pal I, Sengupta A. Clinicopathological and audiological study of tympanosclerrosis. Indian Journal of Otolaryngology and Head and Neck Surgery. 2005;57(3):235-9. Stankovic MD. Hearing results of surgery for tympanosclerosis. Eur Arch Otorhinolaryngol. 2009;266(5):635-40. Swartz JD, Goodman RS, Russell KB, Marlowe FI, Wolfson RJ. High-Resolution Computed-Tomography of the Middle-Ear and Mastoid .2. Tubotympanic Disease. [Article in English] Radiology. 1983;148(2):455-9. Tos M, Lau T, Arndal H, Plate S. Tympanosclerosis of the middle ear: late results of surgical treatment. J Laryngol Otol 1990;104(9):685-9. Walshe P, McConn Walsh R, Brennan P, Walsh M. The role of computerized tomography in the preoperative assessment of chronic suppurative otitis media. Clin Otolaryngol Allied Sci. 2002;27(2):95-7. Wu Y, Yin S, Zhu H, Zhang S. [Tympanosclerosis incidence among patients with chronic suppurative otitis media]. Lin Chuang Er Bi Yan Hou Ke Za Zhi. 2006;20(22):1016-7. Yuen AP, Ho WK, Hui Y, Wei WI, Au DK. Correlation of pure tone audiogram results and hearing benefit of tympanoplasty for chronic suppurative otitis media. Ann Otol Rhinol Laryngol. 2000;109(4):381-384.
Toplam 1 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Klinik Tıp Bilimleri
Bölüm Original Articles
Yazarlar

Sinem Gökçe Kütük Bu kişi benim

Fatih Bora Bu kişi benim

Yayımlanma Tarihi 23 Haziran 2019
Yayımlandığı Sayı Yıl 2019 Cilt: 11 Sayı: 2

Kaynak Göster

APA Gökçe Kütük, S., & Bora, F. (2019). The epidemiology of tympanosclerosis in chronic otitis media patients in the Kars region of Turkey: The role of computerized temporal tomography in diagnosis of tympanosclerosis. Journal of Cellular Neuroscience and Oxidative Stress, 11(2), 825-834. https://doi.org/10.37212/jcnos.683514
AMA Gökçe Kütük S, Bora F. The epidemiology of tympanosclerosis in chronic otitis media patients in the Kars region of Turkey: The role of computerized temporal tomography in diagnosis of tympanosclerosis. J Cell Neurosci Oxid Stress. Haziran 2019;11(2):825-834. doi:10.37212/jcnos.683514
Chicago Gökçe Kütük, Sinem, ve Fatih Bora. “The Epidemiology of Tympanosclerosis in Chronic Otitis Media Patients in the Kars Region of Turkey: The Role of Computerized Temporal Tomography in Diagnosis of Tympanosclerosis”. Journal of Cellular Neuroscience and Oxidative Stress 11, sy. 2 (Haziran 2019): 825-34. https://doi.org/10.37212/jcnos.683514.
EndNote Gökçe Kütük S, Bora F (01 Haziran 2019) The epidemiology of tympanosclerosis in chronic otitis media patients in the Kars region of Turkey: The role of computerized temporal tomography in diagnosis of tympanosclerosis. Journal of Cellular Neuroscience and Oxidative Stress 11 2 825–834.
IEEE S. Gökçe Kütük ve F. Bora, “The epidemiology of tympanosclerosis in chronic otitis media patients in the Kars region of Turkey: The role of computerized temporal tomography in diagnosis of tympanosclerosis”, J Cell Neurosci Oxid Stress, c. 11, sy. 2, ss. 825–834, 2019, doi: 10.37212/jcnos.683514.
ISNAD Gökçe Kütük, Sinem - Bora, Fatih. “The Epidemiology of Tympanosclerosis in Chronic Otitis Media Patients in the Kars Region of Turkey: The Role of Computerized Temporal Tomography in Diagnosis of Tympanosclerosis”. Journal of Cellular Neuroscience and Oxidative Stress 11/2 (Haziran 2019), 825-834. https://doi.org/10.37212/jcnos.683514.
JAMA Gökçe Kütük S, Bora F. The epidemiology of tympanosclerosis in chronic otitis media patients in the Kars region of Turkey: The role of computerized temporal tomography in diagnosis of tympanosclerosis. J Cell Neurosci Oxid Stress. 2019;11:825–834.
MLA Gökçe Kütük, Sinem ve Fatih Bora. “The Epidemiology of Tympanosclerosis in Chronic Otitis Media Patients in the Kars Region of Turkey: The Role of Computerized Temporal Tomography in Diagnosis of Tympanosclerosis”. Journal of Cellular Neuroscience and Oxidative Stress, c. 11, sy. 2, 2019, ss. 825-34, doi:10.37212/jcnos.683514.
Vancouver Gökçe Kütük S, Bora F. The epidemiology of tympanosclerosis in chronic otitis media patients in the Kars region of Turkey: The role of computerized temporal tomography in diagnosis of tympanosclerosis. J Cell Neurosci Oxid Stress. 2019;11(2):825-34.