Abstract Book of 7th Brain Research School (2022-BRS), 27 June and 3 July 2022, Isparta, Turkey (http://2022.brs.org.tr/)

Year 2022, Volume: 14 Issue: 2 (Supplement 1), 1 - 24, 14.07.2022

Anonymes Abstract Book

https://doi.org/10.37212/jcnos.1143834

Abstract

7th Brain Research School (2022-BRS) was performed in Isparta, Turkey between 27 June and 3 July 2022 (http://2022.brs.org.tr/). There were abstracts of 8 speakers, 11 oral presentations, and 3 poster presentations in the 2022-BRS.
Titles of speakers;
1- Mustafa NAZIROĞLU. Fluorescent Ca2+ stains for imaging the mice microglia.
2- Beatrice Mihaela RADU. Low-energy accelerated protons irradiation inhibits DNA repair and diminishes cell proliferation, migration and calcium signaling in brain microvascular endothelial cells.
3- Nashat ABUMARIA. Behavioral assays and animal models of psychiatric disorders.
4- Ferah YILDIRIM. Mapping genome-wide DNA methylation changes in alcohol use disorder (No abstrcat).
5- Marco CANEPARI. Principles of Ca2+ imaging using low-affinity indicators.
6- Denis ROUSSEAU. Western blot analyses in the mitochondria.
7- Xinhua SHU. Protection of p-Coumaric acid against depression and memory impairment via inhibition of neuroinflammation
8- Simon HEBEISEN. State dependent block of voltage gated sodium and calcium channels as modern treatment for
epilepsy.

Titles of oral presentations (OPs);
OP1. Bünyamin AYDIN. Diabetic neuropathic pain and TRPM2 Channel: Focus on selenium.
OP2. Agomelatine attenuates calcium signaling and apoptosis via the inhibition of TRPV1
channel in the hippocampal neurons of rats with chronic mild stress depression model.
OP3. Hatice DALDAL. An interaction between cisplatin-induced optic nerve injury and TRPM2 channel.
OP4. Kemal ERTİLAV. Recent developments on the traumatic brain injury models in the experimental animals.
OP5. Kaan ERBAKAN. Involvement of TRPV1 channel in the etiology of epilepsy.
OP6. Ramazan ÇINAR. Does GSH depletion induce TRPM2 activation in neuronal cells?
OP7. Esin AKBAY ÇETİN. TRP ion channels and approaches in COVID-19.
OP8. Gülin ÖZDAMAR ÜNAL. Early life stress and neuroinflammation.
OP9. Adem AHLATCI. Investigation of TRPM2 cation channel activation in PTZ-induced SH-SY5Y cells by patch-clamp technique: Regulatory role of valproic acid.
OP10. Yener YAZĞAN. Orthodontic teeth movement-induced pain and TRPV1 channel.
OP11. Evaluation of the role of Radish (Raphanus sativus) extract in movement tests in MPTP induced experimental Parkinson's model in Balb/C mice.

Titles of poster presentations (P);
P1- Esin AKBAY ÇETİN. Probable pathways of SARS-CoV-2 to central nervous system.
P2. Yusuf DAL. Low molecular weight heparin treatment reduced apoptosis, oxidative stress, and calcium signaling in the thrombocytes of patients with recurrent pregnancy loss and thrombophilia: Involvements of TRPM2 and TRPV1 channels.
P3. Ferruh KARAMANGİL. Investigation of frequency and diversity of experimental animal models of schizophrenia.

Keywords

Epilepsy, Calcium signaling, Neuroscience, Western blot, Patch-clamp, Laser confocal microscope, Cell culture

Supporting Institution

1- International Brain Research Organization (IBRO). 2- Zeiss (Ankara, Turkey). 3- BSN Health, Analysis and Innovation Ltd. Inc. Göller Bölgesi Teknokenti, Isparta, Turkey. 4- Suleyman Demirel University, Isparta, Turkey.

References

• Nazıroğlu M, Lückhoff A. (2008). A calcium influx pathway regulated separately by oxidative stress and ADP-Ribose in TRPM2 channels: single channel events. Neurochem Res. 33(7):1256-62. https://doi.org/10.1007/s11064-007-9577-5.
• Perraud AL, Fleig A, Dunn CA, et al. (2001). ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology. Nature 411(6837):595-9. https://doi.org/10.1038/35079100.
• Yıldızhan K, Nazıroğlu M. (2020). Glutathione Depletion and Parkinsonian Neurotoxin MPP+-Induced TRPM2 Channel Activation Play Central Roles in Oxidative Cytotoxicity and Inflammation in Microglia. Mol Neurobiol. 57(8):3508-3525. https://doi.org/10.1007/s12035-020-01974-7.