Investigation of the Effect of Dandelion Plant (Taraxacum Offcinale) on Calcium Oxalate Monohydrate Crystal Growth

Öz

The formation of kidney stones is a common diasese. It has accepted that the formation of kidney
stones is a process that consist of nucleation, growth and aggregation of calcium oxalate monohydrate crystals
on epithelial cells at renal papillae in super saturated urine. In spite of the technological developments, the high
recurrence rate of kidney stone formation and the risk factors of all available surgical and medical treatments for
kidney stone disease cause new researches in traditional methods. In this study, the effects of dandelion (Taraxacum
offcinale) plant extract as a natural additive on crystallization of calcium oxalate, which have great importance in
biomineralization, were investigated in vitro.  

Anahtar Kelimeler

• Additive,calcium oxalate,crystallization,dandelion

Kalsiyum Oksalat Monohidrat Kristal Büyümesine Karahindiba (Taraxacum Offcinale) Bitkisinin Etkisinin İncelenmesi

Öz

Böbrek taşları günümüzde önemini koruyan, yaygın bir hastalıktır. Böbrek taşı, aşırı doygun ürin
içerisinde kalsiyum oksalat monohidrat kristallerinin renal papillalardaki epitel hücrelerde çekirdeklenme, büyüme
ve çökme aşamalarından oluşan bir kristalizasyon prosesidir. İlerleyen teknolojiye rağmen böbrek taşlarının
tekrarlanabilirliğinin yüksek olması ile tıbbi ve cerrahi tedavilerin yüksek risk faktörleri taşıması geleneksel
yöntemlerde yeni arayışlara sebep olmuştur. Bu çalışmada, biyomineralizasyon açısından oldukça önemli olan
kalsiyum oksalat kristalizasyonuna doğal katkı maddesi olarak Karahindiba (Taraxacum offcinale) bitki ekstraktının
in vitro koşullarda etkileri incelenmiştir  

Anahtar Kelimeler

• Kalsiyum oksalat,katkı maddesi,karahindiba,kristalizasyon

Kaynakça

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