Epidemiology of Acinetobacter baumannii Isolates in an Intensive Care Unit in Kazakhstan

Yıl 2018, Cilt: 08 Sayı: 03, 83 - 88, 15.09.2018

Nelya Bissenova Aigerim Yergaliyeva

https://doi.org/10.5799/jmid.458451

Öz

    ABSTRACT

Objective: Objectives: Acinetobacter
baumannii is an important pathogen of infections in many hospitals,
especially in intensive care unit patients, conditioned difficulty to control
spread and treatment. The objective of the present study is to report the
prevalence and antibiotic resistance rates of A. baumannii strains in ICU patients during a five-year period in a
tertiary care hospital in Kazakhstan.

Methods: Consecutive,
non – duplicate isolates of A. baumannii
were collected and processed during the course of routine diagnostic work up
from adult patients hospitalized in ICU. Identification of isolates and
antibiotic susceptibility testing were performed by Vitek 2 automated system.

Results: In
total 325 A. baumannii strains were
evaluated. The most frequent of strains were from tracheostomy tubes (67
isolates, 22.1%), followed by tracheal aspirates (58 isolates, 19.1%) and
urinary tract (47, 15.5%). The prevalence of A. baumannii strains in ICU was significantly increased from 6.9%
in 2011 to 34.1% to 2015 (p=0.002). Most of testing isolates were 96.7% and
higher resistant to cephalosporins, carbapenems, quinolones. Lower resistance
50% and highest was obtained to aminoglycosides.

Conclusion: we report for the first time in Central Kazakhstan the
prevalence and resistance rates of A.
baumannii in ICU in a single tertiary hospital. The present report is
alarming because the increasing resistance can lead to no alternative situation
on the choice of drugs for the casual treatment of infections caused by
extremely resistant A. baumannii
strains. J Microbiol Infect Dis 2018; 8(3):83-88.

Anahtar Kelimeler

Acinetobacter baumannii, carbapenems, increasing resistance, intensive care, prevalence

Kaynakça

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