Laryngeal myxoma: a rare entity mimicking Reinke’s edema

Ergin Bilgin; Seda Nur Saka; Şevval Günay; Aleyna Şivetoğlu

doi:10.47582/jompac.1865574

Laryngeal myxoma: a rare entity mimicking Reinke’s edema

Abstract

Laryngeal myxoma is a very rare benign mesenchymal tumor, which can present clinically and endoscopically simulating common glottic pathologies. We describe a case of a 56-year-old female smoker with a history of chronic hoarseness for five years. Videolaryngoscopy demonstrated bilateral vocal fold edema suggestive of Reinke’s edema. A microflap approach was utilized during suspension microlaryngoscopy, where gelatinous material was evacuated after a mucosal incision. Histological examination revealed a hypocellular tumor composed of stellate and spindle cells in a myxoid matrix. The diagnosis of laryngeal myxoma was confirmed based on Alcian blue staining and an immunohistochemical profile showing CD34 positivity and S-100 negativity. After the operation, the patient’s voice quality significantly improved, and no recurrence was observed during the 24-month follow-up period. Laryngeal myxoma should be included in the differential diagnosis of polypoid lesions that simulate Reinke’s edema. Clinical recognition is difficult, and the diagnosis is established histologically. Complete surgical excision by microlaryngoscopy is curative; however, long-term follow-up is necessary.

Keywords

Supporting Institution

N/A

Project Number

N/A

Ethical Statement

Written consent was obtained from the patient participating in this study.

Thanks

N/A

References

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Details

Primary Language

English

Subjects

Otorhinolaryngology

Journal Section

Case Report

Authors

Ergin Bilgin ^*
0000-0001-7191-6209
Türkiye

Seda Nur Saka
0009-0002-2135-0504
Türkiye

Şevval Günay
0009-0002-0954-9860
Türkiye

Aleyna Şivetoğlu
0009-0006-7262-181X
Türkiye

Publication Date

February 20, 2026

Submission Date

January 17, 2026

Acceptance Date

February 13, 2026

Published in Issue

Year 2026 Volume: 7 Number: 1

DOI

https://doi.org/10.47582/jompac.1865574

IZ

https://izlik.org/JA33SZ47TJ

Cite

RIS / Bibtex

APA

Bilgin, E., Saka, S. N., Günay, Ş., & Şivetoğlu, A. (2026). Laryngeal myxoma: a rare entity mimicking Reinke’s edema. Journal of Medicine and Palliative Care, 7(1), 189-191. https://doi.org/10.47582/jompac.1865574

AMA

1.Bilgin E, Saka SN, Günay Ş, Şivetoğlu A. Laryngeal myxoma: a rare entity mimicking Reinke’s edema. J Med Palliat Care / JOMPAC / jompac. 2026;7(1):189-191. doi:10.47582/jompac.1865574

Chicago

Bilgin, Ergin, Seda Nur Saka, Şevval Günay, and Aleyna Şivetoğlu. 2026. “Laryngeal Myxoma: A Rare Entity Mimicking Reinke’s Edema”. Journal of Medicine and Palliative Care 7 (1): 189-91. https://doi.org/10.47582/jompac.1865574.

EndNote

Bilgin E, Saka SN, Günay Ş, Şivetoğlu A (February 1, 2026) Laryngeal myxoma: a rare entity mimicking Reinke’s edema. Journal of Medicine and Palliative Care 7 1 189–191.

IEEE

[1]E. Bilgin, S. N. Saka, Ş. Günay, and A. Şivetoğlu, “Laryngeal myxoma: a rare entity mimicking Reinke’s edema”, J Med Palliat Care / JOMPAC / jompac, vol. 7, no. 1, pp. 189–191, Feb. 2026, doi: 10.47582/jompac.1865574.

ISNAD

Bilgin, Ergin - Saka, Seda Nur - Günay, Şevval - Şivetoğlu, Aleyna. “Laryngeal Myxoma: A Rare Entity Mimicking Reinke’s Edema”. Journal of Medicine and Palliative Care 7/1 (February 1, 2026): 189-191. https://doi.org/10.47582/jompac.1865574.

JAMA

1.Bilgin E, Saka SN, Günay Ş, Şivetoğlu A. Laryngeal myxoma: a rare entity mimicking Reinke’s edema. J Med Palliat Care / JOMPAC / jompac. 2026;7:189–191.

MLA

Bilgin, Ergin, et al. “Laryngeal Myxoma: A Rare Entity Mimicking Reinke’s Edema”. Journal of Medicine and Palliative Care, vol. 7, no. 1, Feb. 2026, pp. 189-91, doi:10.47582/jompac.1865574.

Vancouver

1.Ergin Bilgin, Seda Nur Saka, Şevval Günay, Aleyna Şivetoğlu. Laryngeal myxoma: a rare entity mimicking Reinke’s edema. J Med Palliat Care / JOMPAC / jompac. 2026 Feb. 1;7(1):189-91. doi:10.47582/jompac.1865574