Synthesis of coordination compounds of Zinc(II), Copper(II), Nickel(II), Cobalt(II) and Iron(II) with mixed piperaquine-acetaminophen and piperaquine-acetylsalicylic acid has been studied. The complexes were characterized via: solubility test, melting point determination, conductivity measurement, Atomic Absorption Spectroscopy, UV-Visible Spectroscopy, FTIR Spectroscopy and magnetic susceptibility. The complexes were proposed to have a stoichiometry ratio of 1:1:1 between each metal salt and the ligands with tetrahedral and octahedral geometry following the reaction pattern of MX.yH2O + L1L2/3 to give ML1L2/3X.yH2O. Biological activities of the synthesized complexes have been evaluated against Escherichia coli and Staphylococcus aureus.
Antimalaria Analgesic Mixed ligands Metal complexes Spectroscopy Biological activities
Bölüm | Makaleler |
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Yazarlar | |
Yayımlanma Tarihi | 9 Ocak 2017 |
Gönderilme Tarihi | 7 Ekim 2016 |
Yayımlandığı Sayı | Yıl 2017 Cilt: 4 Sayı: 1 |