Bi(NO3)3•5H2O-catalyzed Mannich Reaction: A Potent Catalyst for Synthesis of β-Aminocarbonyl Compounds

Yıl 2019, Cilt: 6 Sayı: 3, 433 - 438, 20.10.2019

Hasniye Yaşa Kübra Demir

https://doi.org/10.18596/jotcsa.605641

Cited By: 2

Öz

Biologically active
compounds containing nitrogen, natural molecules and drugs are important for
organic synthesis. Mannich reaction is one of the most common methods used for
the synthesis of these compounds. Bi(NO₃)₃ was used as an
efficient catalyst for the one-pot three-component Mannich reactions of ketones
with different aromatic amines and aromatic aldehydes at room temperature. It
is a good method to prepare β-amino carbonyl compounds in excellent yield. The
high efficiency using simple starting materials and a catalytic amount of a
reusable catalyst is especially noteworthy.

Anahtar Kelimeler

Mannich reaction, One-pot synthesis, Bismuth (III) nitrate

Destekleyen Kurum

Scientific Research Projects Coordination Unit of Istanbul University

Proje Numarası

57459

Kaynakça

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