BibTex RIS Kaynak Göster

New antiepileptic drugs in the treatment of Lennox-Gastaut syndrome

Yıl 2009, Cilt: 1 , 0 - , 18.12.2009

Alberto Verrottı , Giangennaro Coppola , Lucia Fıordalıso Claudia D'egıdıo Giulia Loıacono Francesco Chıarellı

Öz

Lennoxa€“Gastaut syndrome is a childhood epileptic encephalopathy characterised by polymorphic seizures and neuropsychological decline. The most characteristic seizures are tonic fits, atypical absences and atonic seizures, in that order. Treatment options for patients with LGS are limited because of the resistance of seizures to pharmacological treatment. Owing to the many seizure types, many drugs are used in combinations that are mostly guided by anecdotal evidence or personal experience. Opinions towards treatment are further complicated because an antiepileptic drug might be of some benefit for the control of one type of seizure while aggravating another type. Concomitantly, polytherapy increases the potential for adverse events. The ultimate goal of epilepsy treatment is to achieve seizure control in a safe manner. Seizure freedom appears to be unrealistic in some refractory epilepsies, especially LGS. In this Review, we discuss newer antiepileptic drugs (Felbamate, Lamotrigine, Levetiracetam, Topiramate, Rufinamide, Vigabatrin, Zonisamide) in the treatment of Lennox-Gastaut syndrome. Investigation of the effects of newer medications might help to identify treatments that, when used in the early stages of the disorder, might have long-term beneficial effects on seizures and the associated comorbidities.

Anahtar Kelimeler

antiepileptic drugs Lennox- Gastaut syndrome epilepsy

Yıl 2009, Cilt: 1 , 0 - , 18.12.2009

Alberto Verrottı , Giangennaro Coppola , Lucia Fıordalıso Claudia D'egıdıo Giulia Loıacono Francesco Chıarellı

Öz

Toplam 0 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Bölüm Reviews
Yazarlar

Alberto Verrottı

Giangennaro Coppola

Lucia Fıordalıso Bu kişi benim

Claudia D'egıdıo Bu kişi benim

Giulia Loıacono Bu kişi benim

Francesco Chıarellı Bu kişi benim

Yayımlanma Tarihi 18 Aralık 2009
Yayımlandığı Sayı Yıl 2009 Cilt: 1

Kaynak Göster

APA Verrottı, A., Coppola, G., Fıordalıso, L., D’egıdıo, C., vd. (2009). New antiepileptic drugs in the treatment of Lennox-Gastaut syndrome. Journal of Pediatric Sciences, 1. https://doi.org/10.17334/jps.17339
AMA Verrottı A, Coppola G, Fıordalıso L, D’egıdıo C, Loıacono G, Chıarellı F. New antiepileptic drugs in the treatment of Lennox-Gastaut syndrome. Journal of Pediatric Sciences. Aralık 2009;1. doi:10.17334/jps.17339
Chicago Verrottı, Alberto, Giangennaro Coppola, Lucia Fıordalıso, Claudia D’egıdıo, Giulia Loıacono, ve Francesco Chıarellı. “New Antiepileptic Drugs in the Treatment of Lennox-Gastaut Syndrome”. Journal of Pediatric Sciences 1, Aralık (Aralık 2009). https://doi.org/10.17334/jps.17339.
EndNote Verrottı A, Coppola G, Fıordalıso L, D’egıdıo C, Loıacono G, Chıarellı F (01 Aralık 2009) New antiepileptic drugs in the treatment of Lennox-Gastaut syndrome. Journal of Pediatric Sciences 1
IEEE A. Verrottı, G. Coppola, L. Fıordalıso, C. D’egıdıo, G. Loıacono, ve F. Chıarellı, “New antiepileptic drugs in the treatment of Lennox-Gastaut syndrome”, Journal of Pediatric Sciences, c. 1, 2009, doi: 10.17334/jps.17339.
ISNAD Verrottı, Alberto vd. “New Antiepileptic Drugs in the Treatment of Lennox-Gastaut Syndrome”. Journal of Pediatric Sciences 1 (Aralık 2009). https://doi.org/10.17334/jps.17339.
JAMA Verrottı A, Coppola G, Fıordalıso L, D’egıdıo C, Loıacono G, Chıarellı F. New antiepileptic drugs in the treatment of Lennox-Gastaut syndrome. Journal of Pediatric Sciences. 2009;1. doi:10.17334/jps.17339.
MLA Verrottı, Alberto vd. “New Antiepileptic Drugs in the Treatment of Lennox-Gastaut Syndrome”. Journal of Pediatric Sciences, c. 1, 2009, doi:10.17334/jps.17339.
Vancouver Verrottı A, Coppola G, Fıordalıso L, D’egıdıo C, Loıacono G, Chıarellı F. New antiepileptic drugs in the treatment of Lennox-Gastaut syndrome. Journal of Pediatric Sciences. 2009;1.