Research Article

In Vitro Comparison of Dusting and Fragmentation Techniques Using Holmium: YAG Laser Lithotripsy: Efficacy and Thermal Impact Assessment

Volume: 18 Number: 2 June 26, 2026
EN

In Vitro Comparison of Dusting and Fragmentation Techniques Using Holmium: YAG Laser Lithotripsy: Efficacy and Thermal Impact Assessment

Abstract

Aim: Due to the potential risks of thermal effects during Ho:YAG laser lithotripsy, different techniques may vary in efficacy and safety. This study compares the stone fragmentation efficiency and temperature elevation associated with dusting and fragmentation techniques using the Ho:YAG laser in an experimental model.

Material and Methods: Using an artificial renal calyx model, ten experimental tubes and phantom stones were prepared for each technique. Energy settings were 0.5 J–20 Hz for the dusting technique and 1 J–10 Hz for the fragmentation technique. Temperature was measured every minute for five minutes, and stone weights were assessed.

Results: The fragmentation technique resulted in significantly greater stone mass reduction from the first minute onward (p < 0.001). Although the average temperature increase was higher in the dusting group, the intergroup difference was insignificant (p = 0.144). In both techniques, the thermal threshold of 43 °C was exceeded at the 2nd to 3rd minute.

Conclusion: The findings of this study underscore the importance of choosing a technique for Ho:YAG laser lithotripsy. The fragmentation technique was more effective for stone disintegration, while the dusting technique posed a higher thermal risk. The Ho:YAG laser method directly impacts clinical success and patient safety, highlighting the need for further research and careful consideration in clinical practice.

Keywords

Supporting Institution

This research was supported by the Scientific Research Projects Coordination Unit of Duzce University (Project No: 2019.04.02.1040).

Project Number

This study was supported by Düzce University BAP - DÜBAP 2019.04.02.1040 Scientific Research Project

References

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  2. Vassar GJ, Chan KF, Teichman JMH, Glickman RD, Weintraub ST, Pfefer TJ, et al. Holmium: YAG lithotripsy: photothermal mechanism. J Endourol. 1999;13(3):181-90. doi:10.1089/end.1999.13.181.
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  4. Aldoukhi AH, Hall TL, Ghani KR, Maxwell AD, MacConaghy B, Roberts WW. Caliceal fluid temperature during high-power Holmium laser lithotripsy in an in vivo porcine model. J Endourol. 2018;32(8):724-9. doi:10.1089/end.2018.0395.
  5. Wen Z, Wang L, Liu Y, Huang J, Chen CX, Wang CJ, et al. A systematic review and meta-analysis of outcomes between dusting and fragmentation in retrograde intrarenal surgery. BMC Urol. 2023;23(1):113. doi:10.1186/s12894-023-01283-w.
  6. Yarmolenko PS, Moon EJ, Landon C, Manzoor A, Hochman DW, Viglianti BL, et al. Thresholds for thermal damage to normal tissues: an update. Int J Hyperthermia. 2011;27(4):320-43. doi:10.3109/02656736.2010.534527.
  7. Hein S, Petzold R, Schoenthaler M, Wetterauer U, Miernik A. Thermal effects of Ho:YAG laser lithotripsy: real-time evaluation in an in vitro model. World J Urol. 2018;36(9):1469-75. doi:10.1007/s00345-018-2303-x.
  8. Rice P, Somani BK, Nagele U, Herrmann TR, Tokas T. Generated temperatures and thermal laser damage during upper tract endourological procedures using the Holmium: Yttrium–Aluminum-Garnet (Ho:YAG) laser: a systematic review of experimental studies. World J Urol. 2022;40(8):1981-92. doi:10.1007/s00345-022-03992-7.

Details

Primary Language

English

Subjects

Health Informatics and Information Systems

Journal Section

Research Article

Publication Date

June 26, 2026

Submission Date

June 30, 2025

Acceptance Date

June 3, 2026

Published in Issue

Year 2026 Volume: 18 Number: 2

APA
Şenoğlu, Y., Dilek, İ. E., Yüksel, A., Baba, D., & Kayıkçı, M. A. (2026). In Vitro Comparison of Dusting and Fragmentation Techniques Using Holmium: YAG Laser Lithotripsy: Efficacy and Thermal Impact Assessment. Konuralp Medical Journal, 18(2), 151-155. https://doi.org/10.18521/ktd.1728985
AMA
1.Şenoğlu Y, Dilek İE, Yüksel A, Baba D, Kayıkçı MA. In Vitro Comparison of Dusting and Fragmentation Techniques Using Holmium: YAG Laser Lithotripsy: Efficacy and Thermal Impact Assessment. Konuralp Medical Journal. 2026;18(2):151-155. doi:10.18521/ktd.1728985
Chicago
Şenoğlu, Yusuf, İsmail Eyüp Dilek, Alpaslan Yüksel, Dursun Baba, and Muhammet Ali Kayıkçı. 2026. “In Vitro Comparison of Dusting and Fragmentation Techniques Using Holmium: YAG Laser Lithotripsy: Efficacy and Thermal Impact Assessment”. Konuralp Medical Journal 18 (2): 151-55. https://doi.org/10.18521/ktd.1728985.
EndNote
Şenoğlu Y, Dilek İE, Yüksel A, Baba D, Kayıkçı MA (June 1, 2026) In Vitro Comparison of Dusting and Fragmentation Techniques Using Holmium: YAG Laser Lithotripsy: Efficacy and Thermal Impact Assessment. Konuralp Medical Journal 18 2 151–155.
IEEE
[1]Y. Şenoğlu, İ. E. Dilek, A. Yüksel, D. Baba, and M. A. Kayıkçı, “In Vitro Comparison of Dusting and Fragmentation Techniques Using Holmium: YAG Laser Lithotripsy: Efficacy and Thermal Impact Assessment”, Konuralp Medical Journal, vol. 18, no. 2, pp. 151–155, June 2026, doi: 10.18521/ktd.1728985.
ISNAD
Şenoğlu, Yusuf - Dilek, İsmail Eyüp - Yüksel, Alpaslan - Baba, Dursun - Kayıkçı, Muhammet Ali. “In Vitro Comparison of Dusting and Fragmentation Techniques Using Holmium: YAG Laser Lithotripsy: Efficacy and Thermal Impact Assessment”. Konuralp Medical Journal 18/2 (June 1, 2026): 151-155. https://doi.org/10.18521/ktd.1728985.
JAMA
1.Şenoğlu Y, Dilek İE, Yüksel A, Baba D, Kayıkçı MA. In Vitro Comparison of Dusting and Fragmentation Techniques Using Holmium: YAG Laser Lithotripsy: Efficacy and Thermal Impact Assessment. Konuralp Medical Journal. 2026;18:151–155.
MLA
Şenoğlu, Yusuf, et al. “In Vitro Comparison of Dusting and Fragmentation Techniques Using Holmium: YAG Laser Lithotripsy: Efficacy and Thermal Impact Assessment”. Konuralp Medical Journal, vol. 18, no. 2, June 2026, pp. 151-5, doi:10.18521/ktd.1728985.
Vancouver
1.Yusuf Şenoğlu, İsmail Eyüp Dilek, Alpaslan Yüksel, Dursun Baba, Muhammet Ali Kayıkçı. In Vitro Comparison of Dusting and Fragmentation Techniques Using Holmium: YAG Laser Lithotripsy: Efficacy and Thermal Impact Assessment. Konuralp Medical Journal. 2026 Jun. 1;18(2):151-5. doi:10.18521/ktd.1728985

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