Antibacterial Activity of Verbascum antinori

Abstract

Objective: In current study, biological screening of the methanol extract obtained from Verbascum antinori Boiss. et Heldr. (Scrophulariaceae) was carry out on antibacterial effects.

Methods: Antibacterial activity of the extract was evaluated for Staphylococcus aureus ATCC 6538P, Proteus vulgaris ATCC 8427, Klebsiella pneumoniae UC57, Micrococcus luteus CCM 169, Escherichia coli ATCC 11230, Listeria monocytogenes ATCC 15313, Bacillus cereus ATCC 7064 and Pseudomonas aeruginosa ATCC 27853 by disk diffusion method.

Results: The extract has potential effect against the Gram-positive bacteria, but no activity was observed against the Gram-negative bacteria used in the present study.

Conclusions: On the basis of the mentioned results, V. antinori may be a potential source of antibacterial agent.

Keywords

• Antibacterial activity,Verbascum antinori

Verbascum antinori Bitkisinin Antibakteriyal Aktivitesi

Abstract

Amaç: Bu çalışmada, Verbascum antinori Boiss. et Heldr. (Scrophulariaceae) bitkisinden elde edilen metanol ekstraktının antibakteriyal aktivitesi araştırılmıştır.

Gereç ve Yöntem: Ekstraktın antibakteriyal aktivitesi, Staphylococcus aureus ATCC 6538P, Proteus vulgaris ATCC 8427, Klebsiella pneumoniae UC57, Micrococcus luteus CCM 169, Escherichia coli ATCC 11230, Listeria monocytogenes ATCC 15313, Bacillus cereus ATCC 7064 ve Pseudomonas aeruginosa ATCC 27853 bakterilerine karşı disk difüzyon metodu kullanılarak belirlenmiştir.

Bulgular: Elde edilen ekstraktın, çalışmada kullanılan Gram-pozitif bakterilere karşı oldukça etkin olduğu, ancak Gram-negatif bakterilere karşı ise etkisiz olduğu saptanmıştır.

Sonuç: V. antinori bitkisinden elde edilen ekstraktın antibakteriyal ajan olarak kullanılabilirliği saptanmış ve ilerki çalışmalarda bu bitkinin antibakteriyal bileşiklerinin belirlenmesine yönelik çalışmaların gerekliliği öngörülmüştür.

Keywords

• Antibakteriyal Aktivite,Verbascum antinori

References

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