The Relationship between Obesity and Cardiovascular Risk in Postmenopausal Women

Year 2019, , 208 - 216, 28.06.2019

Pakize Gamze Erten Bucaktepe , Tahsin Çelepkolu , İlknur Aslan M.halis Tanrıverdi Ahmet Yılmaz , Hamza Aslanhan Veysel Kars

https://doi.org/10.18521/ktd.514048

Abstract

Objective: The
aim of this study was to investigate the relationship between obesity and
cardiovascular risk in postmenopausal women.

            Methods: The study included 43 postmenopausal women who were
admitted to Dicle University Medical School Family Medicine Outpatient Clinic in
2011. Body mass index (BMI), waist and hip circumferences, body fat mass and
percentage, 24-hour arterial tension measurements, homocysteine (Hcy) level,
vitamin B12 level, and Framingham risk score (FRS) were compared between obese
(BMI>30 kg/m²) and non-obese (BMI≤30 kg/m²) patients.

            Results: The patients included 24 (55.8%) obese and 19 (44.2%)
non-obese patients. Abdominal obesity was seen in 29 (67.4%) and truncal
obesity in 33 (76.7%) participants. Family history of cardiac disease was seen
in 25 (58.1%) women, most of whom were obese. Based on FRS, moderate
cardiovascular risk was assessed in 21.6%, but none of the participants were at
high risk. FRS was higher in patients with Hcy levels of ≥15 µmol/L. In
addition, the Hcy values increased with age and there was a negative
correlation between Hcy levels and vitamin B12 status (r=-0.322, p=0.035).

            Conclusion: The results of this study indicate that age- and gender-dependent
differences must be taken into consideration for cardiovascular risk
assessments and postmenopausal women should be informed about obesity and
hypertension in order to improve their quality of life.

Özet

            Amaç:
Bu çalışmada postmenopozal kadınlarda obesite ve kardiyovasküler risk
ilişkisinin incelenmesi amaçlanmıştır.

            Gereç-Yöntem: çalışmaya Dicle Üniversitesi Tıp Fakültesi Aile
Hekimliği Polikliniğine 2011 yılında başvuran 43 postmenopozal kadın dahil
edilmiştir. Beden kitle indeksi (BKİ), bel ve kalça çevresi, vücut yağ kitle ve
yüzdesi, 24-saatlik kan basıncı ölçümleri, homosistein (Hcy) düzeyi, vitamin
B12 düzeyi ve Framingham risk skorlaması (FRS)  obez olan (BKİ>30 kg/m²) ve obez olmayan (BKİ≤30
kg/m²) kadınlarda ölçülerek karşılaştırılmıştır.

Bulgular: Kadınların
24’ü (%55.8) obez ve 19’u (%44.2) non-obezdi. Abdominal obezite 29 (%67.4),
trunkal obezite 33 (%76.7) hastada mevcuttu. Kardiyak hastalık aile öyküsü,
çoğu obez olan 25 (%58.1) kadında tespit edildi. FRS’ye göre orta düzeyde  kardiyovasküler risk %21.6 oranında
saptanırken hiçbir kadın yüksek risk grubunda değildi. FRS, Hcy seviyesi ≥15
µmol/L olan kadınlarda daha yüksekti. Hcy seviyesi yaşla artmaktaydı ve Hcy ile
vitamin B12 arasında negative korelasyon mevcuttu (r=-0.322, p=0.035).

Sonuç: Bu
çalışma kardiyovasküler risk değerlendirmesine yaş ve cinsiyete bağlı
farklılıkların göz önünde bulundurulması ve postmenopozal kadınların, yaşam
kalitelerini arttırmak için obezite ve hipertansiyon konusunda
bilgilendirilmeleri gerektiğini göstermektedir.

Anahtar Kelimeler: Obezite,
Homosistein, Vitamin B12, Kan
basıncı Monitorizasyonu, Framingham Risk Skorlaması.

Keywords

Obesity, Homocysteine, Vitamin B12, Blood Pressure Monitoring

Postmenopozal Kadınlarda Obesite ve Kardiyovasküler Risk İlişkisi

Abstract

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