Kemik ve Yumuşak Doku Tümörlerinde Biyopsi Ve Rezeksiyon Materyallerinin Histopatolojik Karşılaştırılması: Üçüncü Basamak Onkoloji Referans Merkezi Deneyimi “İstanbul Medeniyet Üniversitesi Prof.Dr. Süleyman Yalçın Şehir Hastanesi”

Abstract

Amaç: Üçüncü basamak bir sevk merkezine sevk edilen kemik ve yumuşak doku tümörlerinin biyopsi ve rezeksiyon materyallerinde patoloji sonuçlarının tutarlılığını değerlendirmek Metod: Ocak 2015-Mart 2021 tarihleri arasında İstanbul Prof.Dr. Süleyman Yalçın Şehir Hastanesi Ortopedi ve Travmatoloji Anabilim Dalı'na başvuran 270 hasta retrospektif olarak incelendi. Toplanan veriler, demografik verileri, biyopsi tipini, biyopsi ve rezeksiyonun patoloji raporunu içeriyordu. Bulgular: 125 hastada kemik tümörü saptandı (ortalama yaş: 38.3 yıl, 58 kadın, 67 erkek). Tümör lokalizasyonları en sık alt ekstremitede (%53,6) ve üst ekstremitede (%28), ardından klavikula, kaburga, kalça ve omurgadaydı. Hastalara core needle (n=109) veya insizyonel biyopsi (n=16) yapıldı. Çalışmamızda, core needle ve insizyonel biyopsilerde yeterli biyopsi materyali oranı sırasıyla %89.91 ve %93.75 idi. 145 hastamıza yumuşak doku tümörü nedeniyle biyopsi uygulandı (ortalama yaş: 38.8 yıl, 75 kadın, 70 erkek). Tümör lokalizasyonları en sık alt (%64.1) ve üst ekstremitede (%22) görülmekle birlikte daha az sıklıkta sırasıyla boyun, kalça, retroperitoneal ve skapula bölgelerinde yerleşim göstermekteydi. Tanı amacıyla tru-cut biyopsi (n=136), insizyonel biyopsi (n=7), veya ince iğne aspirasyonu (n=2) yapıldı. İlk biyopsi materyali yeterli olan yumuşak doku tümörlerinin %94,78'inde biyopsi ve rezeksiyon patolojisinin uyumlu olduğu saptandı. Sonuç: Biyopsi sonrası tanısal doğruluğu arttırmak amacıyla çok disiplinli yaklaşım önemli rol oynamaktadır. Uyumsuz klinik ve radyolojik bulgular görülen hastalarda tedavi yaklaşımının doğru planlanabilmesi için biyopsinin tekrar edilmesi gereklidir.

Keywords

• Biyopsi
• Kemik dokusu tümörleri
• Yumuşak doku neoplazileri

Histopathological Comparison Of Biopsy And Resection Materials In Bone And Soft Tissue Tumors: The Experience of a Tertiary Oncology Referral Center “Istanbul Medeniyet University Prof.Dr. Süleyman Yalçın City Hospital”

Abstract

Objective: To evaluate the consistency of pathology results in biopsy and resection materials of bone and soft tissue tumors referred to a tertiarry referral center. Method: 270 patients who were admitted to the Department of Orthopedics and Traumatology of Istanbul Prof. Dr. Suleyman Yalcin City Hospital between January 2015 and March 2021, were retrospectively reviewed. Collected data included demographic data, type of biopsy technique, the pathology report of biopsy and resection. Result: Bone tumors had been detected in 125 patients (mean age: 38.3 years, 58 female, 67 male). Tumor localizations were most common in the lower extremity (53.6%) and upper extremity (28%), followed by clavicle, rib, hip, and vertebra. Core needle (n=109) or incisional biopsy (n=16) was performed. The rate of biopsy material that deemed adequate in core needle and incisional biopsies was 89.91% and 93.75%, respectively. Biopsy was done in 145 patients due to soft tissue tumors. (mean age: 38.8 years, 75 female, 70 male). Tumor localizations were most common in the lower extremity (64.1 %) and upper extremity (22%), followed by neck, hip, retroperitoneal, and scapula. For diagnosis, core needle (n=136), incisional biopsy (n=7) or fine needle aspiration (n=2) was performed. In 94.78% of soft tissue tumors with adequate first biopsy material, the biopsy and resected material pathology was found to be consistent. Conclusion: A multidisciplinary approach plays an important role in increasing the diagnostic accuracy after biopsy in bone and soft tissue tumors. In patients with inconsistent clinical and radiological findings, repeat biopsy is mandatory in order to plan the correct treatment approach.

Keywords

• biopsy;
• bone tissue neoplasms
• soft tissue neoplasms

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