Öz
Henoch-Schonlein purpura is the most common vasculitis in childhood with the pathogenesis of immunoglobulin A deposition in small-vessel wall. As the end-organ vasculature involved, this disease is characterized by palpable purpura, abdominal pain, arthritis, and renal disease. Renal involvement may present with isolated haematuria and/or proteinuria from mild to severe as nephrotic levels. Membranoproliferative glomerulonephritis is the most common cause of chronic glomerulonephritis in older children and young adults and also one of the major causes of nephrotic syndrome. In this case, we reported the concurrent of leukocytoclastic glomerulonephritis. Key Membranoproliferative Glomerulonephritis, Nephrotic Syndrome
Anahtar Kelimeler
Kaynakça
- Cansick JC, Lennon R, Cummins CL, et al. Prognosis, treatment and outcome of childhood mesangiocapillary (membranoproliferative) glomerulonephritis. Nephrol Dial Transplant 2004;19(11):2769- 77.
- Cassidy JT, Petty RE. Leukocytoclastic Vasculitis. In: Casidy JT, Petty RE, Laxer RM, Lindsly CB (eds). Textbook of Pediatric Rheumatology, 5th ed. Philadelphia: Elsevier–Saunders, 2005; 496–520.
- Rostoker G. Schonlein-henoch purpura in children and adults: diagnosis, pathophysiology and management. Bio Drugs. 2001; 15(2): 99–138.
- Davis ID, Avner ED. Membranoproliferative (Mesangiocapillary) glomerulonephritis. In: Kliegman RM, Behrman RE, Jenson HB, Stanton BF (eds). Nelson textbook of pediatrics. 18th edition. Philadelphia: WB Saunders, 2007; 2176-7.
- Ghersetich I, Comacchi C, Katsambas A, et al. Cellular steps in pathogenesis of cutaneous necrotizing vasculitis. Clin Dermatol 1999; 17(5): 597-601.
- Nakajıma A, Adachi M, Tanaka M, et al. Membranoproliferative Glomerulonephritis and Leukocytoclastic Vasculitis without Cryoglobulin in Chronic Hepatitis C Virus Infection. Intern Med. 2003; 42(10): 1042-6.
- Fidan HK.İnfeksiyöz Glomerülonefritler. Turkiye Klinikleri J Pediatr Sci. 2008; 4(1): 59-66.
- Ergin H, Parlaz N, Ergin Ş, et al. Poststreptokoksik septal pannikülit ve lökositoklastik birlikteliği: Bir vaka takdimi. Çocuk Sağlığı ve Hastalıkları Dergisi 2008; 51(1): 48-50. 9. Çimen F, Canbakan S, Pelit A, et al. Küçük Hücreli Akciğer Kanseri ve Lökositoklastik Vaskülit (Bir Olgu Nedeniyle). Solunum Hastalık. 2001; 12(2): 146-50.
- Orfila C, Lepert JC, Modesto A, et al. Henoch-Schönlein purpura and membranoproliferative-like glomerulonephritis. Nephron. 1996; 74(1): 209-13.
- Ozen S, Ruperto N, Dillon MJ, et al. EULAR/PReS endorsed consensus criteria for the classification of childhood vasculitides. Ann Rheum Dis 2006; 65(7): 936-41.
- Tanaka H, Onodera N, Waga S, et al. Glomerulonephritis without IgA deposits in a case of Henoch- Schönlein purpura. Pediatr Nephrol. 1999; 13(7): 597–9.
- West CD, McAdams AJ, Welch TR. Glomerulonephritis in Henoch-Schönlein purpura without mesangial IgA deposition. Pediatr Nephrol 1994; 8(6): 677–83.
Öz
Henoch-Schonlein duvarında immünglobulin A birikimi ile karakterize çocukluk çağının en sık rastlanan vaskülitidir. Hedef organda damarsal yapının tutulması sonucu palpe edilebilen purpura, karın ağrısı, artrit ve böbrek hastalığı görülür. Böbrek tutulumu, izole hematüri ve/veya hafif düzeyden nefrotik düzeylerdeki oranlara varan Membranoproliferatif glomerulonefrit, büyük çocuklarda ve genç erişkinlerde kronik glomerulonefritin en sık sebebidir ve aynı zamanda nefrotik sendromun en önemli sebeplerinden biridir. Bu vakada, lökositoklastik vaskülit ile membranoproliferatif glomerulonefrit birlikteliği sunulmuştur
Anahtar Kelimeler
Kaynakça
- Cansick JC, Lennon R, Cummins CL, et al. Prognosis, treatment and outcome of childhood mesangiocapillary (membranoproliferative) glomerulonephritis. Nephrol Dial Transplant 2004;19(11):2769- 77.
- Cassidy JT, Petty RE. Leukocytoclastic Vasculitis. In: Casidy JT, Petty RE, Laxer RM, Lindsly CB (eds). Textbook of Pediatric Rheumatology, 5th ed. Philadelphia: Elsevier–Saunders, 2005; 496–520.
- Rostoker G. Schonlein-henoch purpura in children and adults: diagnosis, pathophysiology and management. Bio Drugs. 2001; 15(2): 99–138.
- Davis ID, Avner ED. Membranoproliferative (Mesangiocapillary) glomerulonephritis. In: Kliegman RM, Behrman RE, Jenson HB, Stanton BF (eds). Nelson textbook of pediatrics. 18th edition. Philadelphia: WB Saunders, 2007; 2176-7.
- Ghersetich I, Comacchi C, Katsambas A, et al. Cellular steps in pathogenesis of cutaneous necrotizing vasculitis. Clin Dermatol 1999; 17(5): 597-601.
- Nakajıma A, Adachi M, Tanaka M, et al. Membranoproliferative Glomerulonephritis and Leukocytoclastic Vasculitis without Cryoglobulin in Chronic Hepatitis C Virus Infection. Intern Med. 2003; 42(10): 1042-6.
- Fidan HK.İnfeksiyöz Glomerülonefritler. Turkiye Klinikleri J Pediatr Sci. 2008; 4(1): 59-66.
- Ergin H, Parlaz N, Ergin Ş, et al. Poststreptokoksik septal pannikülit ve lökositoklastik birlikteliği: Bir vaka takdimi. Çocuk Sağlığı ve Hastalıkları Dergisi 2008; 51(1): 48-50. 9. Çimen F, Canbakan S, Pelit A, et al. Küçük Hücreli Akciğer Kanseri ve Lökositoklastik Vaskülit (Bir Olgu Nedeniyle). Solunum Hastalık. 2001; 12(2): 146-50.
- Orfila C, Lepert JC, Modesto A, et al. Henoch-Schönlein purpura and membranoproliferative-like glomerulonephritis. Nephron. 1996; 74(1): 209-13.
- Ozen S, Ruperto N, Dillon MJ, et al. EULAR/PReS endorsed consensus criteria for the classification of childhood vasculitides. Ann Rheum Dis 2006; 65(7): 936-41.
- Tanaka H, Onodera N, Waga S, et al. Glomerulonephritis without IgA deposits in a case of Henoch- Schönlein purpura. Pediatr Nephrol. 1999; 13(7): 597–9.
- West CD, McAdams AJ, Welch TR. Glomerulonephritis in Henoch-Schönlein purpura without mesangial IgA deposition. Pediatr Nephrol 1994; 8(6): 677–83.
Ayrıntılar
| Birincil Dil | Türkçe |
|---|---|
| Bölüm | Makaleler |
| Yazarlar | |
| Yayımlanma Tarihi | 1 Aralık 2013 |
| Yayımlandığı Sayı | Yıl 2013 Cilt: 5 Sayı: 3 |