Artificial Intelligence in Patient Communication: Performance of GPT-3.5 and GPT-4 in Coronary Bypass Surgery

Year 2025, Volume: 17 Issue: 1, 100 - 105, 27.03.2025

Muhammet Fethi Sağlam , Emrah Uğuz , Kemal Erdoğan , Hüseyin Ünsal Erçelik , Murat Yücel , Cevat Ahmet Sert , Fatih Yamac , Erol Sener

Abstract

Objective: This study aims to evaluate the ability of GPT-3.5 and GPT-4 to provide accurate, comprehensible, and clinically relevant responses to common patient questions about coronary bypass surgery.
Method: A cross-sectional study was conducted at Ankara Yıldırım Beyazıt University Bilkent City Hospital with 80 cardiovascular surgery specialists. Participants rated the responses of GPT-3.5 and GPT-4 to 10 common patient questions about coronary bypass surgery based on four criteria: accuracy, understandability, clinical appropriateness, and overall evaluation. Statistical analysis included independent t-tests, Cronbach’s Alpha reliability analysis, and Cohen’s d effect size calculation.
Results: GPT-4 significantly outperformed GPT-3.5 across all metrics. The mean scores for GPT-4 were higher in accuracy (3.02 vs. 1.77), understandability (2.99 vs. 1.81), clinical appropriateness (2.96 vs. 1.78), and overall evaluation (2.98 vs. 1.77) (p<0.05 for all). Cronbach's Alpha values indicated good internal consistency (≥0.69 for all metrics), and Cohen’s d effect sizes demonstrated large differences (1.54 to 1.65).
Conclusions: GPT-4 shows superior potential compared to GPT-3.5 in answering patient questions about coronary bypass surgery. Despite its strengths, occasional inaccuracies and incomplete responses highlight the need for further refinement. Future research should integrate patient feedback and evaluate the real-world clinical impact of these models to optimize their application in healthcare.

Keywords

Coronary bypass surgery , Artificial intelligence , GPT-3.5 , GPT-4 , Patient communication

Hasta İletişiminde Yapay Zeka: Koroner Bypass Cerrahisinde GPT-3.5 ve GPT-4'ün Performansı

Abstract

Amaç: Bu çalışma, GPT-3.5 ve GPT-4'ün koroner bypass cerrahisiyle ilgili yaygın hasta sorularına doğru, anlaşılır ve klinik olarak uygun yanıtlar verme yeteneğini değerlendirmeyi amaçlamaktadır.
Yöntem: Ankara Yıldırım Beyazıt Üniversitesi Bilkent Şehir Hastanesi'nde 80 kalp ve damar cerrahisi uzmanı ile kesitsel bir çalışma yürütülmüştür. Katılımcılar GPT-3.5 ve GPT-4'ün koroner bypass cerrahisi ile ilgili 10 yaygın hasta sorusuna verdiği yanıtları dört kritere göre değerlendirmiştir: doğruluk, anlaşılabilirlik, klinik uygunluk ve genel değerlendirme. İstatistiksel analiz bağımsız t-testlerini, Cronbach Alfa güvenilirlik analizini ve Cohen's d etki büyüklüğü hesaplamasını içermektedir.
Bulgular: GPT-4 tüm ölçütlerde GPT-3.5'ten önemli ölçüde daha iyi performans göstermiştir. GPT-4 için ortalama puanlar doğruluk (3,02'ye karşı 1,77), anlaşılabilirlik (2,99'a karşı 1,81), klinik uygunluk (2,96'ya karşı 1,78) ve genel değerlendirme (2,98'e karşı 1,77) açısından daha yüksekti (tümü için p<0,05). Cronbach's Alpha değerleri iyi bir iç tutarlılık (tüm ölçütler için ≥0,69) ve Cohen's d etki büyüklükleri büyük farklılıklar (1,54 ila 1,65) göstermiştir.
Sonuç: GPT-4, koroner bypass cerrahisi ile ilgili hasta sorularını yanıtlamada GPT-3.5'e kıyasla üstün potansiyel göstermektedir. Güçlü yönlerine rağmen, zaman zaman ortaya çıkan yanlışlıklar ve eksik yanıtlar daha fazla iyileştirme ihtiyacının altını çizmektedir. Gelecekteki araştırmalar, hasta geri bildirimlerini entegre etmeli ve sağlık hizmetlerinde uygulamalarını optimize etmek için bu modellerin gerçek dünyadaki klinik etkilerini değerlendirmelidir.

Keywords

Koroner bypass cerrahisi , Yapay zeka , GPT-3.5 , GPT-4 , Hasta iletişimi

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