Galactogogues

Yıl 2018, Cilt: 10 Sayı: 6, 28 - 31, 15.11.2018

Doç. Dr. Sinan Mahir Kayıran

Öz

Abstract

Galactogogues are medications or products believed to assist initiation and aug-ment the maternal milk. Human milk production is a complex physiological processthat is affected by emotional and hormonal factors especially the prolactin. The help for the women having low milk supply may be evaluated by lactation experts for individual needs. In this review, we aimed to discuss the current knowledge about galactogogues.

Anahtar Kelimeler

Galactogogue, breastmilk, prolactin

Galaktogoglar

Öz

Öz

Galaktogoglar, anne sütünün başlamasına yardımcı olmak ya da artırmak amacıyla kullanılan ürünlerdir. Anne sütü üretimi, emosyonel ve özellikle de prolaktin olmak üzere hormonal faktörlerin etkilediği kompleks fizyolojik bir süreçtir. Sütüaz olan annelere destek, emzirme danışmanları tarafından bireysel gereksinimlere göre değerlendirilmelidir. Bu derlemede, galaktogoglar konusundaki güncel bilgiyi tartışmayı amaçladık,

Anahtar Kelimeler

Galaktogog, anne sütü, prolaktin

Kaynakça

• Kaynaklar 1.Brodribb Wendy. ABM Clinical Protocol 9: Use of Galacto-gogues in Initiating or Augmenting Maternal Milk Producti-on, Second Revision 2018. Breastfeeding Medicine 2018; 13:307-14. 2.Kent JC. How breastfeeding works. J Midwifery Womens He-alth 2007; 52:5 64-70. 3.Czank C, Henderson JL, Kent JC, et al. Hormonal control ofthe lactation cycle. In: Hale & Hartmann’s Textbook of Hu-man Lactation, Hale TW, Hartmann PE, eds. Amarillo, TX:Hale Publishing, 2007: 89-111. 4.da Silva OP, Knoppert DC, Angelini MM, et al. Effect of dom-peridone on milk production in mothers of premature newborns:A randomized, double-blind, placebo-controlled trial. Can MedAssoc J 2001; 164: 17-21. 5.Kauppila A, Kivinen S, Ylikorkala O. Metoclorpramide increa-ses prolactin release and milk secretion in puerperium witho-ut stimulating the secretion of thytropin and thyroid hormo-nes. J Clin Endocrinol Metab 1981; 52: 436-39. 6.Donovan TJ, Buchanan K. Medications for increasing milksupply in mothers expressing breastmilk for their preterm hos-pitalized infants. Cochrane Database Syst Rev 2012; 3:CD005544. 7.Grzeskowiak L, Smithers L, Amir L, et al. Domperidone forincreasing breast milk volume in mothers expressing breastmilk for their preterm infants: A systematic review andmeta-analysis. BJOG 2018 [Epub ahead of print];DOI:10.1111/1471-0528.15177. 8.Jantarasaengaram S, Sreewapa P. Effects of domperidone onaugmentation of lactation following cesarean delivery at fullterm. Int J Gynaecol Obstet 2012; 116: 240-43. 9.Knoppert DC, Page A, Warren J, et al. The effect of two dom-peridone doses on maternal milk production. J Hum Lact 2013;29: 38-44. 10.Ingram J, Taylor H, Churchill C, et al. Metoclopramide or dom-peridone for increasing maternal breast milk output: A ran-domized controlled trial. Arch Dis Child Fetal Neonatal Ed2012; 97: F241-F245. 11.Asztalos EV, Campell-Yeo M, da Silva OP, et al. Enhancinghuman milk production with domperidone in mothers of pre-term infants. J Hum Lact 2017; 33: 181-87. 12.Doggrell SA, Hancox JC. Cardiac safety concerns for dom-peridone, an antiemetic and prokinetic, and galactogogue me-dicine. Expert Opinion On Drug Safety 2014; 13: 131-38. 13.Lewis PJ, Devenish C, Kahn C. Controlled trial of metoclop-ramide in the initiation of breast feeding. Br J Clin Pharma-col 1980; 9: 217-19. 14.Hansen WF, McAndrew S, Harris K, Zimmerman MB. Metoc-lopramide effect on breastfeeding the preterm infant: a ran-domized trial. Obstet Gynecol 2005; 105: 383-89. 15.Sakha K, Behbahan AG. Training for perfect breastfeeding ormetoclopramide: which one can promote lactation in nursingmothers? Breastfeed Med 2008; 3: 120-23. doi:10.1089/bfm.2007.0020. 16.Seema Patwari AK, Satyanarayana L. Relactation: an effective intervention to promote exclusive breastfeeding. J TropPediatr 1997; 43: 213-16. doi: 10.1093/tropej/43.4.213. 17-Fife S, Gill P, Hopkins M, Angello C, Boswell S, Nelson KM.Metoclopramide to augment lactation, does it work? A ran-domized trial. J Matern Fetal Neonatal Med 2011; 24:1317-20. doi: 10.3109/14767058.2010.549255. Epub 2011 Mar17. 18.Ingram J, Taylor H, Churchill C, Pike A, Greenwood R. Me-toclopramide or domperidone for increasing maternal breastmilk output: a randomised controlled trial. Arch Dis Child Fe-tal Neonatal Ed 2012; 97: F241-5. doi: 10.1136/archdischild-2011-300601. Epub 2011 Dec 5. 19.https://www.fda.gov/Drugs/DevelopmentApprovalProcess/HowDrugsareDevelopedandApproved/ApprovalApplications/InvestigationalNewDrugINDApplication/ucm368736.htm (ac-cessed 30 September, 2018) 20.Smolina K, Mintzes K, Hanley GE, et al. The association bet-ween domperidone and ventricular arrhythmia in the postpar-tum period. Pharmacoepidemiol Drug Saf 2016; 25: 1210-14. 21.Thaweekul P, Thaweekul Y, Sritipsukho P. The efficacy of hos-pital-based food program as galactogogues in early period oflactation. J Med Assoc Thai 2014; 97: 478-82. 22.Özalkaya E, Aslandoğdu Z, Özkoral A, et al. Effect of a ga-lactogogue herbal tea on breast milk production and prolac-tin secretion by mothers of preterm babies. Niger J Clin Pract2018; 21: 38-42. 23. Mortel M, Mehta SD. Systematic review of the efficacy of her-bal galactogogues. J Hum Lact 2013; 29: 154-62. 24.Haastrup MB, Pottegard A, Damkier P. Alcohol and breast-feeding. Basic Clin Pharmocol Toxicol 2014; 114: 168-73. 25.Anderson PO. Herbal use during breastfeeding. Breastfeed Med2017; 12: 507-509. 26.Tiran D. The use of fenugreek for breast feeding women. Com-plement Ther Nurs Midwifery 2003 ;9: 155-56.