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Light and electronmicroscopical investigations on the cytoprotective effects of prostaglandin e2 and dimethyl sulfoxide in carbon tetrachloride-induced liver necrosis

Yıl 1991, Cilt: 4 Sayı: 4, 141 - 148, 01.12.1991

Öz

Studies have shown that prostaglandin E2 (PG E2) can prevent liver necrosis due to several agents. Dimethyl sulfoxide (DMSO) is also known with its cytoprotective efficiency. To determine the degree of cytoprotective effectivenesses of these two agents, 20 female rats were divided into 5 groups.

Livers of rats treated only with carbon tetrachloride showed severe necrosis. In groups pretreated with prostaglandin E2 and dimethyl sulfoxide, degree of necrosis was very low. Especially prostaglandin E2 could perform this cytoprotection very well.

It is concluded that these two cytoprotective agents could prevent carbon tetrachloride-induced liver cell necrosis in the rats at different degrees.

Kaynakça

  • Robert A. et al. Cytoprotection by prostaglandins. Gastroenterol 1979; 77: 761-767.
Yıl 1991, Cilt: 4 Sayı: 4, 141 - 148, 01.12.1991

Öz

Kaynakça

  • Robert A. et al. Cytoprotection by prostaglandins. Gastroenterol 1979; 77: 761-767.
Toplam 1 adet kaynakça vardır.

Ayrıntılar

Konular Klinik Tıp Bilimleri
Bölüm Editör'den
Yazarlar

S. Arbak Bu kişi benim

Yayımlanma Tarihi 1 Aralık 1991
Yayımlandığı Sayı Yıl 1991 Cilt: 4 Sayı: 4

Kaynak Göster

APA Arbak, S. (1991). Light and electronmicroscopical investigations on the cytoprotective effects of prostaglandin e2 and dimethyl sulfoxide in carbon tetrachloride-induced liver necrosis. Marmara Medical Journal, 4(4), 141-148.
AMA Arbak S. Light and electronmicroscopical investigations on the cytoprotective effects of prostaglandin e2 and dimethyl sulfoxide in carbon tetrachloride-induced liver necrosis. Marmara Med J. Aralık 1991;4(4):141-148.
Chicago Arbak, S. “Light and Electronmicroscopical Investigations on the Cytoprotective Effects of Prostaglandin E2 and Dimethyl Sulfoxide in Carbon Tetrachloride-Induced Liver Necrosis”. Marmara Medical Journal 4, sy. 4 (Aralık 1991): 141-48.
EndNote Arbak S (01 Aralık 1991) Light and electronmicroscopical investigations on the cytoprotective effects of prostaglandin e2 and dimethyl sulfoxide in carbon tetrachloride-induced liver necrosis. Marmara Medical Journal 4 4 141–148.
IEEE S. Arbak, “Light and electronmicroscopical investigations on the cytoprotective effects of prostaglandin e2 and dimethyl sulfoxide in carbon tetrachloride-induced liver necrosis”, Marmara Med J, c. 4, sy. 4, ss. 141–148, 1991.
ISNAD Arbak, S. “Light and Electronmicroscopical Investigations on the Cytoprotective Effects of Prostaglandin E2 and Dimethyl Sulfoxide in Carbon Tetrachloride-Induced Liver Necrosis”. Marmara Medical Journal 4/4 (Aralık 1991), 141-148.
JAMA Arbak S. Light and electronmicroscopical investigations on the cytoprotective effects of prostaglandin e2 and dimethyl sulfoxide in carbon tetrachloride-induced liver necrosis. Marmara Med J. 1991;4:141–148.
MLA Arbak, S. “Light and Electronmicroscopical Investigations on the Cytoprotective Effects of Prostaglandin E2 and Dimethyl Sulfoxide in Carbon Tetrachloride-Induced Liver Necrosis”. Marmara Medical Journal, c. 4, sy. 4, 1991, ss. 141-8.
Vancouver Arbak S. Light and electronmicroscopical investigations on the cytoprotective effects of prostaglandin e2 and dimethyl sulfoxide in carbon tetrachloride-induced liver necrosis. Marmara Med J. 1991;4(4):141-8.