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The efficacy of almitrine bismesylate on hypoxemia, exercise performance and sleep desaturation of patients with severe copd

Yıl 1993, Cilt: 6 Sayı: 2, 53 - 58, 01.04.1993

B. Ceyhan T. Çelikel A. S. Fak

Öz

Almitrine bismesylate (AB), a peripheral chemorecep- tor agonist, has been shown to improve arterial blood gases in patients with chronic obstructive pulmonary disease (COPD). This study was designed to test the efficacy of almitrine bismesylate in patients with COPD. AB was administered 3 mg/kg po bid to 17 patients (12 men, 5 women, mean predicted FEV1%:33%(21-51). Arterial blood gas analysis revealed incline of Pa02 from 55.2111.7 mmHg to

62.7110.4 mmHg and incline of oxygen saturation (Sa02) from 84.319.7% to 89.716.1% (p<0.003, p<0.002) 3 hours after intake of a single dose, 7 patients dropped out of the study. Mean Pa02 increased 10.2 mmHg (p<0.003), mean PaC02 decreased 8.5 mmHg (p<0.003) and oxygen saturation increased 5.9%(p<0.009) 3 months after in 10 patients.

Anahtar Kelimeler

Almitrine bismesylate chronic obstructive pulmonary disease

Kaynakça

  • Melot C. Maege R, Hallemans R, Mois P. Lejeune P. Beneficial effects of almitrine bismesylate on pulmonary gas exchange in COPD. Bur J Resp Dis 1983 ;126(64) : 249-254.

Yıl 1993, Cilt: 6 Sayı: 2, 53 - 58, 01.04.1993

B. Ceyhan T. Çelikel A. S. Fak

Öz

Kaynakça

  • Melot C. Maege R, Hallemans R, Mois P. Lejeune P. Beneficial effects of almitrine bismesylate on pulmonary gas exchange in COPD. Bur J Resp Dis 1983 ;126(64) : 249-254.
Toplam 1 adet kaynakça vardır.

Ayrıntılar

Konular Klinik Tıp Bilimleri
Bölüm Derleme
Yazarlar

B. Ceyhan Bu kişi benim

T. Çelikel Bu kişi benim

A. S. Fak Bu kişi benim

Yayımlanma Tarihi 1 Nisan 1993
Yayımlandığı Sayı Yıl 1993 Cilt: 6 Sayı: 2

Kaynak Göster

APA Ceyhan, B., Çelikel, T., & Fak, A. S. (1993). The efficacy of almitrine bismesylate on hypoxemia, exercise performance and sleep desaturation of patients with severe copd. Marmara Medical Journal, 6(2), 53-58.
AMA Ceyhan B, Çelikel T, Fak AS. The efficacy of almitrine bismesylate on hypoxemia, exercise performance and sleep desaturation of patients with severe copd. Marmara Med J. Nisan 1993;6(2):53-58.
Chicago Ceyhan, B., T. Çelikel, ve A. S. Fak. “The Efficacy of Almitrine Bismesylate on Hypoxemia, Exercise Performance and Sleep Desaturation of Patients With Severe Copd”. Marmara Medical Journal 6, sy. 2 (Nisan 1993): 53-58.
EndNote Ceyhan B, Çelikel T, Fak AS (01 Nisan 1993) The efficacy of almitrine bismesylate on hypoxemia, exercise performance and sleep desaturation of patients with severe copd. Marmara Medical Journal 6 2 53–58.
IEEE B. Ceyhan, T. Çelikel, ve A. S. Fak, “The efficacy of almitrine bismesylate on hypoxemia, exercise performance and sleep desaturation of patients with severe copd”, Marmara Med J, c. 6, sy. 2, ss. 53–58, 1993.
ISNAD Ceyhan, B. vd. “The Efficacy of Almitrine Bismesylate on Hypoxemia, Exercise Performance and Sleep Desaturation of Patients With Severe Copd”. Marmara Medical Journal 6/2 (Nisan 1993), 53-58.
JAMA Ceyhan B, Çelikel T, Fak AS. The efficacy of almitrine bismesylate on hypoxemia, exercise performance and sleep desaturation of patients with severe copd. Marmara Med J. 1993;6:53–58.
MLA Ceyhan, B. vd. “The Efficacy of Almitrine Bismesylate on Hypoxemia, Exercise Performance and Sleep Desaturation of Patients With Severe Copd”. Marmara Medical Journal, c. 6, sy. 2, 1993, ss. 53-58.
Vancouver Ceyhan B, Çelikel T, Fak AS. The efficacy of almitrine bismesylate on hypoxemia, exercise performance and sleep desaturation of patients with severe copd. Marmara Med J. 1993;6(2):53-8.