Two ribosomal kinase fractions have been partially purified from reticulocyte lysates by DEAE-cellulose and phosphocellulose column chromatography. These fractions autophosphorylated the majority of the bands and phosphorylated EF-1 and elF-2|3. Addition of GSSG (oxidized glutathione) produced a general decrease in phosphorylation. However, phosphorylation of elF-2|3 was enhanced in the presence of GSSG.
initiation factor-2 elongation factor- 1 phosphorylation casein kinase I GSSg
Konular | Klinik Tıp Bilimleri |
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Bölüm | Derleme |
Yazarlar | |
Yayımlanma Tarihi | 1 Aralık 1993 |
Yayımlandığı Sayı | Yıl 1993 Cilt: 6 Sayı: 4 |