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Single dose intravenous ondansetron in the prophylaxis of postoperative nausea and vomiting

Yıl 1994, Cilt: 7 Sayı: 1, 33 - 35, 01.01.1994

M. Erenus Ö. Leylek H. Canatay M.A. Akman Y. Göğüs

Öz

The purpose of the present randomized, double blind placebo controlled study was to compare the effect of ondansetron, a 5 HT 3 subtype of serotonin receptor antagonist, with placebo, in preventing postoperative nausea and vomiting. A total of forty-nine patients undergoing total abdominal hysterectomy were assigned to the study. The patients received either 4 mg intravenous ondansetron or a matching placebo, prior to induction of anesthesia. The number of episodes of emesis and nausea were recorded at 1 hour, 4 hour and 8 hour after recovery from anesthesia. The nausea and womiting scores at 1h 4h and 8h in the ondansetron group were significantly lower than the placebo group (p<0.05). The incidence of the most frequently occuring side effects in the ondansetron group were headache in 15.38 % and dizziness in 7.7 % of the patients. In conclusion, ondansetron appears to be an effective agent in the prophylaxis of postoperative nausea and vomiting in gynecologic operations.

Anahtar Kelimeler

Prophylaxis emesis ondansetron

Kaynakça

  • Mathia WL, Bell SK, Leak WD. Effects of preoperative metoclopralde and droperidol on postoperative nauesa and vomiting in ambulatory surgery patients. Am Assoc nurse Anesth J 1988; 56:325-333.

Yıl 1994, Cilt: 7 Sayı: 1, 33 - 35, 01.01.1994

M. Erenus Ö. Leylek H. Canatay M.A. Akman Y. Göğüs

Öz

Kaynakça

  • Mathia WL, Bell SK, Leak WD. Effects of preoperative metoclopralde and droperidol on postoperative nauesa and vomiting in ambulatory surgery patients. Am Assoc nurse Anesth J 1988; 56:325-333.
Toplam 1 adet kaynakça vardır.

Ayrıntılar

Konular Klinik Tıp Bilimleri
Bölüm Derleme
Yazarlar

M. Erenus Bu kişi benim

Ö. Leylek Bu kişi benim

H. Canatay Bu kişi benim

M.A. Akman Bu kişi benim

Y. Göğüs Bu kişi benim

Yayımlanma Tarihi 1 Ocak 1994
Yayımlandığı Sayı Yıl 1994 Cilt: 7 Sayı: 1

Kaynak Göster

APA Erenus, M., Leylek, Ö., Canatay, H., Akman, M., vd. (1994). Single dose intravenous ondansetron in the prophylaxis of postoperative nausea and vomiting. Marmara Medical Journal, 7(1), 33-35.
AMA Erenus M, Leylek Ö, Canatay H, Akman M, Göğüs Y. Single dose intravenous ondansetron in the prophylaxis of postoperative nausea and vomiting. Marmara Med J. Ocak 1994;7(1):33-35.
Chicago Erenus, M., Ö. Leylek, H. Canatay, M.A. Akman, ve Y. Göğüs. “Single Dose Intravenous Ondansetron in the Prophylaxis of Postoperative Nausea and Vomiting”. Marmara Medical Journal 7, sy. 1 (Ocak 1994): 33-35.
EndNote Erenus M, Leylek Ö, Canatay H, Akman M, Göğüs Y (01 Ocak 1994) Single dose intravenous ondansetron in the prophylaxis of postoperative nausea and vomiting. Marmara Medical Journal 7 1 33–35.
IEEE M. Erenus, Ö. Leylek, H. Canatay, M. Akman, ve Y. Göğüs, “Single dose intravenous ondansetron in the prophylaxis of postoperative nausea and vomiting”, Marmara Med J, c. 7, sy. 1, ss. 33–35, 1994.
ISNAD Erenus, M. vd. “Single Dose Intravenous Ondansetron in the Prophylaxis of Postoperative Nausea and Vomiting”. Marmara Medical Journal 7/1 (Ocak 1994), 33-35.
JAMA Erenus M, Leylek Ö, Canatay H, Akman M, Göğüs Y. Single dose intravenous ondansetron in the prophylaxis of postoperative nausea and vomiting. Marmara Med J. 1994;7:33–35.
MLA Erenus, M. vd. “Single Dose Intravenous Ondansetron in the Prophylaxis of Postoperative Nausea and Vomiting”. Marmara Medical Journal, c. 7, sy. 1, 1994, ss. 33-35.
Vancouver Erenus M, Leylek Ö, Canatay H, Akman M, Göğüs Y. Single dose intravenous ondansetron in the prophylaxis of postoperative nausea and vomiting. Marmara Med J. 1994;7(1):33-5.