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2-deoxyglucose transport in human peripheral lymphocytes rat lymphocytes and thymocytes; effects of insulin on 2-deoxyglucose transport in these cells

Yıl 1996, Cilt: 9 Sayı: 1, 23 - 28, 01.01.1996

G. Hergenç K. Emerk

Öz

Glucose transport into human peripheral lymphocytes, rat lymphocytes, and rat thymocytes were investigated using 2-deoxyglucose (2-DOG) in the transport studies. Our results showed rat thymocytes to have a high affinity and a low affinity system for transporting 2-DOG with Km values of

0.11 mM and 7.14 mM respectively. Both of the systems were inhibited by phloretin (0.1 mM), a specific inhibitor of carrier mediated transport. Human peripheral lymphocytes and rat lymphoctes transported 2-DOG with Km values of 5.26 mM and 3.57 mM respectively. While insulin had no effect on this transport in thymocytes and lymphocytes, it inhibited the efflux of 2-DOG from the cells.

Anahtar Kelimeler

2-DOG uptake lymphocytes thymocytes transport insulin

Kaynakça

  • Carruthers A. Facilitated diffusion of glucose. Physiol Reviews 1990:70:1135-1176.

Yıl 1996, Cilt: 9 Sayı: 1, 23 - 28, 01.01.1996

G. Hergenç K. Emerk

Öz

Kaynakça

  • Carruthers A. Facilitated diffusion of glucose. Physiol Reviews 1990:70:1135-1176.
Toplam 1 adet kaynakça vardır.

Ayrıntılar

Konular Klinik Tıp Bilimleri
Bölüm Derleme
Yazarlar

G. Hergenç Bu kişi benim

K. Emerk Bu kişi benim

Yayımlanma Tarihi 1 Ocak 1996
Yayımlandığı Sayı Yıl 1996 Cilt: 9 Sayı: 1

Kaynak Göster

APA Hergenç, G., & Emerk, K. (1996). 2-deoxyglucose transport in human peripheral lymphocytes rat lymphocytes and thymocytes; effects of insulin on 2-deoxyglucose transport in these cells. Marmara Medical Journal, 9(1), 23-28.
AMA Hergenç G, Emerk K. 2-deoxyglucose transport in human peripheral lymphocytes rat lymphocytes and thymocytes; effects of insulin on 2-deoxyglucose transport in these cells. Marmara Med J. Ocak 1996;9(1):23-28.
Chicago Hergenç, G., ve K. Emerk. “2-Deoxyglucose Transport in Human Peripheral Lymphocytes Rat Lymphocytes and Thymocytes; Effects of Insulin on 2-Deoxyglucose Transport in These Cells”. Marmara Medical Journal 9, sy. 1 (Ocak 1996): 23-28.
EndNote Hergenç G, Emerk K (01 Ocak 1996) 2-deoxyglucose transport in human peripheral lymphocytes rat lymphocytes and thymocytes; effects of insulin on 2-deoxyglucose transport in these cells. Marmara Medical Journal 9 1 23–28.
IEEE G. Hergenç ve K. Emerk, “2-deoxyglucose transport in human peripheral lymphocytes rat lymphocytes and thymocytes; effects of insulin on 2-deoxyglucose transport in these cells”, Marmara Med J, c. 9, sy. 1, ss. 23–28, 1996.
ISNAD Hergenç, G. - Emerk, K. “2-Deoxyglucose Transport in Human Peripheral Lymphocytes Rat Lymphocytes and Thymocytes; Effects of Insulin on 2-Deoxyglucose Transport in These Cells”. Marmara Medical Journal 9/1 (Ocak 1996), 23-28.
JAMA Hergenç G, Emerk K. 2-deoxyglucose transport in human peripheral lymphocytes rat lymphocytes and thymocytes; effects of insulin on 2-deoxyglucose transport in these cells. Marmara Med J. 1996;9:23–28.
MLA Hergenç, G. ve K. Emerk. “2-Deoxyglucose Transport in Human Peripheral Lymphocytes Rat Lymphocytes and Thymocytes; Effects of Insulin on 2-Deoxyglucose Transport in These Cells”. Marmara Medical Journal, c. 9, sy. 1, 1996, ss. 23-28.
Vancouver Hergenç G, Emerk K. 2-deoxyglucose transport in human peripheral lymphocytes rat lymphocytes and thymocytes; effects of insulin on 2-deoxyglucose transport in these cells. Marmara Med J. 1996;9(1):23-8.