Araştırma Makalesi
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Yıl 1998, Cilt: 11 Sayı: 2, 77 - 82, 01.03.1998

Öz

Kaynakça

  • Berman JD, Waddel D, Hanson BD. Biochemical Mechanisms of the antileishmanial activity of sodium stibagluconate. Antimicrob Agents Chemother 1985; 27(6): 916-920.

SERUM SELENIUM, ZINC, COPPER AND IRON CONCENTRATIONS AND SOME RELATED ANTIOXIDAN TENZYMES IN PATIENTS WITH CUTANEOUS LEISHMANIASIS

Yıl 1998, Cilt: 11 Sayı: 2, 77 - 82, 01.03.1998

Öz

Objective: This study has been carried out to measure the alterations of some trace element concentrations, their related antioxidant enzyme activities, and carrier proteins in patients with cutaneous leishmaniasis (CL).

Methods: Serum selenium, copper and zinc concentrations were determined by Atomic Absorption Spectrometer. Erythrocyte Cu-Zn superoxide dismutase (Cu-Zn SOD), glutathione peroxidase (GSH-Px) and catalase (CAT) activities and ceruloplasmin (Cp) levels were measured with enzymatic colorimetric methods and transferrin (Tf) levels were measured with turbidimetric method.

Results: Erythrocyte Cu-Zn SOD activities, serum copper concentrations and Cp levels were found to be significantly higher in patients group, than those of controls. However, GSH-Px and CAT activities, and selenium, zinc, iron and Tf levels were lower in patients according to the control subjects. There were positive important correlations between Cu-Zn SOD and Cp, Cu-Zn SOD and copper, Cp and copper, GSH-Px and selenium, and iron and CAT in patients group.

Conclusion: Our results showed that serum

essential trace elements selenium, zinc, copper and iron concentrations and their related enzymes Cu-Zn SOD, GSH-Px and CAT activities change in CL patients. The changes may be a part of defense strategies of organism and are induced by the hormone-like substances.

Kaynakça

  • Berman JD, Waddel D, Hanson BD. Biochemical Mechanisms of the antileishmanial activity of sodium stibagluconate. Antimicrob Agents Chemother 1985; 27(6): 916-920.
Toplam 1 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Klinik Tıp Bilimleri
Bölüm Derleme
Yazarlar

A. Koçyiğit Bu kişi benim

O. Erel Bu kişi benim

MS. Gürel Bu kişi benim

S. Avcı Bu kişi benim

N. Aktepe Bu kişi benim

Yayımlanma Tarihi 1 Mart 1998
Yayımlandığı Sayı Yıl 1998 Cilt: 11 Sayı: 2

Kaynak Göster

APA Koçyiğit, A., Erel, O., Gürel, M., Avcı, S., vd. (1998). SERUM SELENIUM, ZINC, COPPER AND IRON CONCENTRATIONS AND SOME RELATED ANTIOXIDAN TENZYMES IN PATIENTS WITH CUTANEOUS LEISHMANIASIS. Marmara Medical Journal, 11(2), 77-82.
AMA Koçyiğit A, Erel O, Gürel M, Avcı S, Aktepe N. SERUM SELENIUM, ZINC, COPPER AND IRON CONCENTRATIONS AND SOME RELATED ANTIOXIDAN TENZYMES IN PATIENTS WITH CUTANEOUS LEISHMANIASIS. Marmara Med J. Mart 1998;11(2):77-82.
Chicago Koçyiğit, A., O. Erel, MS. Gürel, S. Avcı, ve N. Aktepe. “SERUM SELENIUM, ZINC, COPPER AND IRON CONCENTRATIONS AND SOME RELATED ANTIOXIDAN TENZYMES IN PATIENTS WITH CUTANEOUS LEISHMANIASIS”. Marmara Medical Journal 11, sy. 2 (Mart 1998): 77-82.
EndNote Koçyiğit A, Erel O, Gürel M, Avcı S, Aktepe N (01 Mart 1998) SERUM SELENIUM, ZINC, COPPER AND IRON CONCENTRATIONS AND SOME RELATED ANTIOXIDAN TENZYMES IN PATIENTS WITH CUTANEOUS LEISHMANIASIS. Marmara Medical Journal 11 2 77–82.
IEEE A. Koçyiğit, O. Erel, M. Gürel, S. Avcı, ve N. Aktepe, “SERUM SELENIUM, ZINC, COPPER AND IRON CONCENTRATIONS AND SOME RELATED ANTIOXIDAN TENZYMES IN PATIENTS WITH CUTANEOUS LEISHMANIASIS”, Marmara Med J, c. 11, sy. 2, ss. 77–82, 1998.
ISNAD Koçyiğit, A. vd. “SERUM SELENIUM, ZINC, COPPER AND IRON CONCENTRATIONS AND SOME RELATED ANTIOXIDAN TENZYMES IN PATIENTS WITH CUTANEOUS LEISHMANIASIS”. Marmara Medical Journal 11/2 (Mart 1998), 77-82.
JAMA Koçyiğit A, Erel O, Gürel M, Avcı S, Aktepe N. SERUM SELENIUM, ZINC, COPPER AND IRON CONCENTRATIONS AND SOME RELATED ANTIOXIDAN TENZYMES IN PATIENTS WITH CUTANEOUS LEISHMANIASIS. Marmara Med J. 1998;11:77–82.
MLA Koçyiğit, A. vd. “SERUM SELENIUM, ZINC, COPPER AND IRON CONCENTRATIONS AND SOME RELATED ANTIOXIDAN TENZYMES IN PATIENTS WITH CUTANEOUS LEISHMANIASIS”. Marmara Medical Journal, c. 11, sy. 2, 1998, ss. 77-82.
Vancouver Koçyiğit A, Erel O, Gürel M, Avcı S, Aktepe N. SERUM SELENIUM, ZINC, COPPER AND IRON CONCENTRATIONS AND SOME RELATED ANTIOXIDAN TENZYMES IN PATIENTS WITH CUTANEOUS LEISHMANIASIS. Marmara Med J. 1998;11(2):77-82.