Year 2025,
Volume: 10 Issue: 1, 410 - 415, 30.04.2025
Ecenur Esra Sarikaya
,
Halil İbrahim Gökçe
Project Number
project number 0854-YL 22.
References
-
Byers, C.G., Wilson, C.C., & Stephens, M.B. (2011). Obesity in dogs: Part 1: Exploring the causes and consequences of canine obesity. Veterinary Medicine, 106(4), 184-192.
-
Buishand, F. O., & Kirpensteijn, J. (2023). Canine and feline insulinoma. In: E. Monnet (Ed.). Small Animal Soft Tissue Surgery, (2nd ed., pp.785-797). Balckwell Publishing.
-
Chun, J.L., Bang, H.T., Ji ,S.Y., Jeong, J.Y., Kim, M., Kim, B., Lee, S.D., Lee, Y.K., Reddy, K.E., & Kim, K.Y. (2019). A simple method to evaluate body condition score to maintain the optimal body weight in dogs. Journal of Animal Sciences & Technology, 61(6), 366-37. https://doi.org/10.5187/jast.2019.61.6.366.
-
De Marchi, P.N., Machado L.H.A., Holsback, L., Calesso, J.R., Fagnani, R., Junior A.Z., & Cardoso, M.J.L. (2020). Metabolic profile and adipokine levels in overweight and obese dogs. Turkish Journal of Veterinary & Animal Sciences, 44, 1093-1099. https://doi.org/10.3906/vet-2004-44
-
German, A.J., Holden, S.L., Wiseman-Orr, M.L., Reid, J., Nolan, A.M., Biourge, V., Morris, P.J., & Scott, E.M. (2012). Quality of life is reduced in obese dogs but improves after successful weight loss. The Veterinary Journal, 192, 428–434. https://doi.org/10.1016/j.tvjl.2011.09.015
-
Gonzalez-Gil, A.M., & Elizondo-Montemayor, L. (2020). The Role of Exercise in the Interplay between Myokines, Hepatokines, Osteokines, Adipokines, and Modulation of Inflammation for Energy Substrate Redistribution and Fat Mass Loss: A Review. Nutrients, 12(6), 1899. https://doi.org/10.3390/nu12061899
-
Kennerman, E. (2006). Obez köpeklerde serum lipoprotein ve fruktozamin düzeylerinin belirlenmesi. İstanbul Üniversitesi Veteriner Fakültesi Dergisi, 32(2), 53-59.
-
Loftus J.P., & Wakshlag, J.J. (2015). Canine and feline obesity: a review of pathophysiology, epidemiology, and clinical management. Veterinary Medicine: Research and Reports, 6, 49-60. https://doi.org/10.2147/VMRR.S40868
-
Mawby, D.I., Bartges, J.W, Avignon, A., Laflamme, D.P., Moyers, T.D., & Cottrell, T. (2004). Comparison of Various Methods for Estimating Body Fat in Dogs. Journal of American Animal Hospital Association, 40(2), 109-114. http://dx.doi.org/10.5326/0400109
-
Mori, N., Takemitsu, H., Okada, Y., Yamamoto, I., & Arai, T. (2013). A comparison of metabolic parameters between obese and non-obese healthy domestic dogs in Japan. Asian Journal of Animal and Veterinary Advances, 8(7), 863-873. https:/doi.org/10.3923/ajava.2013.863.873
-
Muñoz-Prieto, A., Nielsen, L.R., Dąbrowski, R., Bjørnvad, C.R., Söder, J., Lamy, E., Monkeviciene, I., jubić, B.B., Vasiu, L., Savic, S., Busato, F.,Yilmaz, Z., Bravo-Cantero, A.F., Öhlund, M., Lucena, S., Zelvyte, S., Aladrović, J., Lopez-Jornet, P., Caldin, M., Lavrador, C., Karveliene, B., Mrljak, V., Mazeikiene, J., & Tvarijonaviciute, A. (2018). European dog owner perceptions of obesity and factors associated with human and canine obesity. Scientific reports, 8,1-10. https:/doi.org/10.1038/s41598-018-31532-0
-
Oh, W. (2011). Prevalence and risk factors for obesity in dogs and cats. In 36th World Small Animal Veterinary Congress, Jeju/Korea. pp: 244-246.
-
Preet, G.S., Turkar, S., Gupta, S., & Kumar, S. (2021). Dog obesity: Epidemiology, risk factors, diagnosis and management: A review paper. The Pharma Innovation Journal, 10(5), 698-705.
-
Rafaj, R.B., Kules, J., Turkovic, V., & Rebselj, B. (2016). Prospective hematologic and biochemical evaluation of spontaneously overweight and obese dogs. Veterinary Arhive, 86(3),383-394.
-
• Ricci, R., Gottardo, F., Ferlito, J.C., Stefani, A., Ravarotto, L., & Andrighetto, I. (2007). Body condition score (BCS) and metabolic status of shelter dogs. Italian Journal of Animal Science (6(1), 859-861. https://doi.org/10.4081/ijas.2007.1s.859
-
Ramos, J.R., & Castillo, V. (2020). Evaluation of insulin resistance in overweight and obese dogs. International Journal of Veterinary Sciences Research, 6(1), 58-63. https:/doi.org/10.17352/ijvsr.000055
-
Robertson, I.D. (2003). The association of exercise, diet and other factors with owner-perceived obesity in privately owned dogs from metropolitan Perth, WA, Preventive Veterinary Medicine, 58(1-2), 75-83. https:/doi.org/ 10.1016/S0167-5877(03)00009-6
-
Ronja, N., & Kölle, P. (2021). Obesity in dogs-A review of underlying reasons. Tierarztl Prax Ausg K Kleintiere Heimtiere, 49(4), 284-293. https:/doi.org/ 10.1055/a-1548-2293
-
Tunca, M. (2019). Klinik Olarak Normal Vücut Kondisyonuna Sahip ve Obez Köpeklerde Rutin Biyo-Belirteçler ile Asimetrik Dimetil Arjinin (Adma) ve Oksidatif Stres Parametrelerinin Değerlendirilmesi. Doktora tezi, Uludağ Üniversitesi, Sağlık Bilimleri Enstitüsü.
-
Shmalberg, J., (2013). Treatment of obesity. Today’s Veterinary Practice, 60-65.
-
Usui, S., Yasuda, H., & Koketsu, Y. (2015). Lipoprotein cholesterol and triglyceride concentrations associated with dog body condition score; effect of recommended fasting duration on sample concentrations in Japanese private clinics. Journal of Veterinary Medical Science, 77(9),1063-1069. https:/doi.org/ 10.1292/jvms.15-0032
-
Verkest, K.R., Fleemana, L.M., Mortona, J.M., Ishiokab, & K., Rand. J.S. (2011). Compensation for obesity-induced insulin resistance in dogs: assessment of the effects of leptin, adiponectin, and glucagon-like peptide-1 using path analysis. Domestic Animal Endocrinology, 41, 24 –34. https:/doi.org/10.1016/j.domaniend.2011.02.001
-
Williams, K., & Buzhardt, L. (2022). Body condition scores. Vca Animal hospital. https://vcahospitals.com/know-your-pet/body-condition-scores
Yamka, R.M., Friesen, K.G. & Frantz, N.Z. (2006). Identification of canine markers related to obesity and the effects of weight loss on the markers of interest. International Journal of Appled Research in Veteterinary Medicine, 4,282-292.
-
Zoran, D.L. (2010). Obesity in dogs and cats: a metabolic and endocrine disorder. Veterinary Clinics of North America Small Animal Practice, 40(2), 221-239. https:/doi.org/10.1016/j.cvsm.2009.10.009
Alterations of lipid profile in overweight and obese dogs
Year 2025,
Volume: 10 Issue: 1, 410 - 415, 30.04.2025
Ecenur Esra Sarikaya
,
Halil İbrahim Gökçe
Abstract
The purpose of the study was to determine the alterations of lipid profile in overweight and obese dogs. Obesity is defined as abnormal or excessive fat accumulation in the body. It is a chronic health problem for both human and animals. Dogs with restricted movements and fed high-energy diets are particularly at a high risk. In the study, 30 dogs of different ages, breeds and genders were used. Dogs were divided into 3 groups equally as ideal weight, overweight and obese according to the body condition score (BCS) chart. Serum samples were collected from all dogs and used to analyze lipid profile parameters using a biochemistry analyzer. In the study, significant increases were detected in total-C (p<0.01), VLDL (p<0.05), and LDL (p<0.05) in obese dogs compared to those of both control and overweight dogs (Table 1). The numbers of dogs with increases in lipid profile parameters were higher in obese dogs than in overweight dogs. In obese dogs, very strong positive correlations were also detected between some of lipid profile parameters. In conclusion, it has been revealed that there are significant alterations in lipid profile parameters in both overweight and obese dogs. The levels of these changes are thought to be related to the severity and progression of obesity in dogs. Presence of strong correlations between lipid profile parameters indicated that total-C, HDL, VLDL, LDL, total-C/LDL and Tg values can be used to evaluate alterations in lipid profile parameters in obese dogs.
Ethical Statement
This study was approved by the Animal Ethics Committee (AEC), Burdur Mehmet Akif University, Türkiye (No:929/2022).
Supporting Institution
Burdur Mehmet Akif Ersoy University, Scientific Research Projects Coordinator ship
Project Number
project number 0854-YL 22.
Thanks
This research study was supported by Burdur Mehmet Akif Ersoy University, Scientific Research Projects Coordinator ship with project number 0854-YL 22.
References
-
Byers, C.G., Wilson, C.C., & Stephens, M.B. (2011). Obesity in dogs: Part 1: Exploring the causes and consequences of canine obesity. Veterinary Medicine, 106(4), 184-192.
-
Buishand, F. O., & Kirpensteijn, J. (2023). Canine and feline insulinoma. In: E. Monnet (Ed.). Small Animal Soft Tissue Surgery, (2nd ed., pp.785-797). Balckwell Publishing.
-
Chun, J.L., Bang, H.T., Ji ,S.Y., Jeong, J.Y., Kim, M., Kim, B., Lee, S.D., Lee, Y.K., Reddy, K.E., & Kim, K.Y. (2019). A simple method to evaluate body condition score to maintain the optimal body weight in dogs. Journal of Animal Sciences & Technology, 61(6), 366-37. https://doi.org/10.5187/jast.2019.61.6.366.
-
De Marchi, P.N., Machado L.H.A., Holsback, L., Calesso, J.R., Fagnani, R., Junior A.Z., & Cardoso, M.J.L. (2020). Metabolic profile and adipokine levels in overweight and obese dogs. Turkish Journal of Veterinary & Animal Sciences, 44, 1093-1099. https://doi.org/10.3906/vet-2004-44
-
German, A.J., Holden, S.L., Wiseman-Orr, M.L., Reid, J., Nolan, A.M., Biourge, V., Morris, P.J., & Scott, E.M. (2012). Quality of life is reduced in obese dogs but improves after successful weight loss. The Veterinary Journal, 192, 428–434. https://doi.org/10.1016/j.tvjl.2011.09.015
-
Gonzalez-Gil, A.M., & Elizondo-Montemayor, L. (2020). The Role of Exercise in the Interplay between Myokines, Hepatokines, Osteokines, Adipokines, and Modulation of Inflammation for Energy Substrate Redistribution and Fat Mass Loss: A Review. Nutrients, 12(6), 1899. https://doi.org/10.3390/nu12061899
-
Kennerman, E. (2006). Obez köpeklerde serum lipoprotein ve fruktozamin düzeylerinin belirlenmesi. İstanbul Üniversitesi Veteriner Fakültesi Dergisi, 32(2), 53-59.
-
Loftus J.P., & Wakshlag, J.J. (2015). Canine and feline obesity: a review of pathophysiology, epidemiology, and clinical management. Veterinary Medicine: Research and Reports, 6, 49-60. https://doi.org/10.2147/VMRR.S40868
-
Mawby, D.I., Bartges, J.W, Avignon, A., Laflamme, D.P., Moyers, T.D., & Cottrell, T. (2004). Comparison of Various Methods for Estimating Body Fat in Dogs. Journal of American Animal Hospital Association, 40(2), 109-114. http://dx.doi.org/10.5326/0400109
-
Mori, N., Takemitsu, H., Okada, Y., Yamamoto, I., & Arai, T. (2013). A comparison of metabolic parameters between obese and non-obese healthy domestic dogs in Japan. Asian Journal of Animal and Veterinary Advances, 8(7), 863-873. https:/doi.org/10.3923/ajava.2013.863.873
-
Muñoz-Prieto, A., Nielsen, L.R., Dąbrowski, R., Bjørnvad, C.R., Söder, J., Lamy, E., Monkeviciene, I., jubić, B.B., Vasiu, L., Savic, S., Busato, F.,Yilmaz, Z., Bravo-Cantero, A.F., Öhlund, M., Lucena, S., Zelvyte, S., Aladrović, J., Lopez-Jornet, P., Caldin, M., Lavrador, C., Karveliene, B., Mrljak, V., Mazeikiene, J., & Tvarijonaviciute, A. (2018). European dog owner perceptions of obesity and factors associated with human and canine obesity. Scientific reports, 8,1-10. https:/doi.org/10.1038/s41598-018-31532-0
-
Oh, W. (2011). Prevalence and risk factors for obesity in dogs and cats. In 36th World Small Animal Veterinary Congress, Jeju/Korea. pp: 244-246.
-
Preet, G.S., Turkar, S., Gupta, S., & Kumar, S. (2021). Dog obesity: Epidemiology, risk factors, diagnosis and management: A review paper. The Pharma Innovation Journal, 10(5), 698-705.
-
Rafaj, R.B., Kules, J., Turkovic, V., & Rebselj, B. (2016). Prospective hematologic and biochemical evaluation of spontaneously overweight and obese dogs. Veterinary Arhive, 86(3),383-394.
-
• Ricci, R., Gottardo, F., Ferlito, J.C., Stefani, A., Ravarotto, L., & Andrighetto, I. (2007). Body condition score (BCS) and metabolic status of shelter dogs. Italian Journal of Animal Science (6(1), 859-861. https://doi.org/10.4081/ijas.2007.1s.859
-
Ramos, J.R., & Castillo, V. (2020). Evaluation of insulin resistance in overweight and obese dogs. International Journal of Veterinary Sciences Research, 6(1), 58-63. https:/doi.org/10.17352/ijvsr.000055
-
Robertson, I.D. (2003). The association of exercise, diet and other factors with owner-perceived obesity in privately owned dogs from metropolitan Perth, WA, Preventive Veterinary Medicine, 58(1-2), 75-83. https:/doi.org/ 10.1016/S0167-5877(03)00009-6
-
Ronja, N., & Kölle, P. (2021). Obesity in dogs-A review of underlying reasons. Tierarztl Prax Ausg K Kleintiere Heimtiere, 49(4), 284-293. https:/doi.org/ 10.1055/a-1548-2293
-
Tunca, M. (2019). Klinik Olarak Normal Vücut Kondisyonuna Sahip ve Obez Köpeklerde Rutin Biyo-Belirteçler ile Asimetrik Dimetil Arjinin (Adma) ve Oksidatif Stres Parametrelerinin Değerlendirilmesi. Doktora tezi, Uludağ Üniversitesi, Sağlık Bilimleri Enstitüsü.
-
Shmalberg, J., (2013). Treatment of obesity. Today’s Veterinary Practice, 60-65.
-
Usui, S., Yasuda, H., & Koketsu, Y. (2015). Lipoprotein cholesterol and triglyceride concentrations associated with dog body condition score; effect of recommended fasting duration on sample concentrations in Japanese private clinics. Journal of Veterinary Medical Science, 77(9),1063-1069. https:/doi.org/ 10.1292/jvms.15-0032
-
Verkest, K.R., Fleemana, L.M., Mortona, J.M., Ishiokab, & K., Rand. J.S. (2011). Compensation for obesity-induced insulin resistance in dogs: assessment of the effects of leptin, adiponectin, and glucagon-like peptide-1 using path analysis. Domestic Animal Endocrinology, 41, 24 –34. https:/doi.org/10.1016/j.domaniend.2011.02.001
-
Williams, K., & Buzhardt, L. (2022). Body condition scores. Vca Animal hospital. https://vcahospitals.com/know-your-pet/body-condition-scores
Yamka, R.M., Friesen, K.G. & Frantz, N.Z. (2006). Identification of canine markers related to obesity and the effects of weight loss on the markers of interest. International Journal of Appled Research in Veteterinary Medicine, 4,282-292.
-
Zoran, D.L. (2010). Obesity in dogs and cats: a metabolic and endocrine disorder. Veterinary Clinics of North America Small Animal Practice, 40(2), 221-239. https:/doi.org/10.1016/j.cvsm.2009.10.009