Ten Years of Surgical Immunological and Survival Results in Renal Transplantation

Öz

Introduction: The aim of this study was to determine renal transplantation results that we performed in ourcenter. Material- Methods: A retrospective review of the results of renal transplantation between 1996 and 2006 was conducted.The evaluation was about both grafts and patients survival and immunologic, surgical complications in 1, 5, 10 years follow-up. Results: A total of 157 renal transplantation patients were included in the study.To 139 patients (89%) living related donor, and to 18 patients (11%) cadaveric renal transplantation was done. The mean age of the patients during the time of the operations was 30,4 years (range 14-60). The mean follow-up time was 55 months. In 1,5,10 years follow-up, the grafts survival rates of transplantations from living donors were 92%,80%,50%, and also the patients survival rates were 95%,90%,80% respectively. In 1,5 years follow-up, the graft survival rates of transplantations that we had done from cadavers were 89%,62% and the patients survival rates were 100%,87% respectively. Surgical complications developed in 43 patients, while in other 114 patients not. The most common surgical complications was lymphocele in 17 patients (10.8%) that was followed by ureterovesicalstenosis in 10 patients (6,4%), urinoma in 6 patients (3,8%), surgical site infection in 5 patients (3,2%), renal artery stenosis in 3 patients (1,9%), renal vein thrombosis in 2 patients (1,3%) respectively. Conclusion: We can prevent the harmful effects of surgical complications and rejections over the graft function and graft survival when we diagnose and treat them early.

Anahtar Kelimeler

• Renal transplantation,complication,survival

RENAL TRANSPLANTASYONDA ON YILLIK CERRAHİ İMMUNOLOJİK VE SAĞKALIM SONUÇLARI

Öz

Amaç : Kliniğimizde yapılan Renal transplantasyon sonuçlarını incelemek ve litaretüre kazandırmak Materyal ve metod: Bu çalışmada 1996 ile 2006 tarihleri arasında kliniğinimizde yapılan renal transplantasyon hastalarının sonuçları değerlendirildi. Renal transplantasyon yapılan hastaların sonuçları; 1,5,10 yıllık greft ve hasta sağkalımı, immunolojik ve cerrahi komplikasyonlar yönünden incelendi. Bulgular: Toplam hasta sayısı 157 olup 18(%11)’i kadavradan 139 (%89)’u canlıdan elde edilen böbrekler ile renal transplantasyon yapılmıştır. Yüzonüçü erkek 44’ü kadın olup yaş ortalaması 30.49.8 yıldır. Renal transplantasyon yapılan en genç hasta 14 yaşında iken en yaşlısı 60 yaşındadır. Ortalama takip süresi 55 aydır. Canlı donörlerden yapılan renal transplantasyonda 1,5,10 yıllık greft sağkalım oranları sırasıyla %92,%80,%50 olup 1,5,10 yıllık hasta sağkalım oranları sırasıyla %95,%90,%80dir.Kadavradan kaynaklı böbrekler ile yapılan renal transplantasyonda 1,5 yıllık greft sağkalım oranları sırasıyla %89, %62 olup 1 ve 5 yıllık hasta sağkalım oranları sırası ile %100 ve %87 dir. Hastaların 43’ünde cerrahi komplikasyon gelişirken 114 hastada gelişmedi. Cerrahi komplikasyon içinde 17 hasta (%10,8) ile lenfosel ensık görüleni olup bunu sıklık sırasına göre 10 hasta (%6,4) üreterovezikal darlık, 6 hasta (%3,8) ürinom, 5 hasta (%3,2) yara yeri enfeksiyonu, 3 hasta (%1,9) renal arter stenozu, 2 hasta (%1,3) renal ven trombozu takip etmektedir. Sonuç: Renal transplantasyon sonrası cerrahi komplikasyonların ve rejeksiyonların erken tanı ve tedavisi ile, greft fonksiyonu ve greft sağkalım süresi üzerindeki olumsuz etkiler önlenebilir.

Anahtar Kelimeler

• Renal transplantasyon,komplikasyon,sağkalım

Kaynakça

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