Case Report

Squamous Cell Carcinoma of The Skin Mimicking Breast Cancer: A Case Report

Volume: 9 Number: 3 December 30, 2022
EN TR

Squamous Cell Carcinoma of The Skin Mimicking Breast Cancer: A Case Report

Abstract

Squamous cell carcinoma (SCC) is the second most common skin cancer and it often occurs in sun-exposed areas such as head and neck skin. Invasive SCC located on breast skin is a rare entity and may clinically mimic breast cancer. We report a case of a 39 years old female with a non-eroded, vegetative, growing lesion on the right breast skin, initially mimicking breast cancer both clinically and histopathologically. After surgery with clear margins, adjuvant radiotherapy was administered, by considering the pathological risk factors for recurrence. At 14 months, the patient is disease-free and under regular follow-up. Invasive SCC of the breast skin is a rare entity and may have different etiology/behavior or directly develop de novo when compared to SCCs located on sun-exposed skin. Medical history and physical examination in conjunction with histopathological examination of the biopsy specimen are critical for the accuracy of the diagnosis and the correct treatment decision in patients presenting with a mass invading breast skin.

Keywords

References

  1. 1. Que SKT, Zwald FO, Schmults CD. Cutaneous squamous cell carcinoma: Incidence, risk factors, diagnosis, and staging. J Am Acad Dermatol. 2018;78(2):237-47.
  2. 2. Melo Neto B, Oliveira Gda P, Vieira SC, Leal LR, Melo Junior JA, Vieira CF. Epidermoid carcinoma of the skin mimicking breast cancer. An Bras Dermatol. 2013;88(2):250-2.
  3. 3. Cherpelis BS, Marcusen C, Lang PG. Prognostic factors for metastasis in squamous cell carcinoma of the skin. Dermatol Surg. 2002;28(3):268-73.
  4. 4. Alam M, Ratner D. Cutaneous squamous-cell carcinoma. N Engl J Med. 2001;344(13):975-83.
  5. 5. Work G, Invited R, Kim JYS, Kozlow JH, Mittal B, Moyer J, et al. Guidelines of care for the management of cutaneous squamous cell carcinoma. J Am Acad Dermatol. 2018;78(3):560-78.

Details

Primary Language

English

Subjects

​Internal Diseases

Journal Section

Case Report

Publication Date

December 30, 2022

Submission Date

December 29, 2021

Acceptance Date

July 29, 2022

Published in Issue

Year 2022 Volume: 9 Number: 3

APA
Türkkan, G., Gözübüyük, F., Çınbay, K., Özen, E. E., Özdemir, F., Alkan, A., Ünçel, M., Bacakszılar Sarı, F., Tekin, L., Dinç Elibol, F., Dere, Ö., Eren Kupık, G., Tanrıverdi, Ö., & Nazlı, O. (2022). Squamous Cell Carcinoma of The Skin Mimicking Breast Cancer: A Case Report. Medical Journal of Mugla Sitki Kocman University, 9(3), 304-308. https://doi.org/10.47572/muskutd.978712
AMA
1.Türkkan G, Gözübüyük F, Çınbay K, et al. Squamous Cell Carcinoma of The Skin Mimicking Breast Cancer: A Case Report. MMJ. 2022;9(3):304-308. doi:10.47572/muskutd.978712
Chicago
Türkkan, Görkem, Furkan Gözübüyük, Kutluhan Çınbay, et al. 2022. “Squamous Cell Carcinoma of The Skin Mimicking Breast Cancer: A Case Report”. Medical Journal of Mugla Sitki Kocman University 9 (3): 304-8. https://doi.org/10.47572/muskutd.978712.
EndNote
Türkkan G, Gözübüyük F, Çınbay K, Özen EE, Özdemir F, Alkan A, Ünçel M, Bacakszılar Sarı F, Tekin L, Dinç Elibol F, Dere Ö, Eren Kupık G, Tanrıverdi Ö, Nazlı O (December 1, 2022) Squamous Cell Carcinoma of The Skin Mimicking Breast Cancer: A Case Report. Medical Journal of Mugla Sitki Kocman University 9 3 304–308.
IEEE
[1]G. Türkkan et al., “Squamous Cell Carcinoma of The Skin Mimicking Breast Cancer: A Case Report”, MMJ, vol. 9, no. 3, pp. 304–308, Dec. 2022, doi: 10.47572/muskutd.978712.
ISNAD
Türkkan, Görkem - Gözübüyük, Furkan - Çınbay, Kutluhan - Özen, Emine Erva - Özdemir, Fatih - Alkan, Ali - Ünçel, Melek et al. “Squamous Cell Carcinoma of The Skin Mimicking Breast Cancer: A Case Report”. Medical Journal of Mugla Sitki Kocman University 9/3 (December 1, 2022): 304-308. https://doi.org/10.47572/muskutd.978712.
JAMA
1.Türkkan G, Gözübüyük F, Çınbay K, Özen EE, Özdemir F, Alkan A, Ünçel M, Bacakszılar Sarı F, Tekin L, Dinç Elibol F, Dere Ö, Eren Kupık G, Tanrıverdi Ö, Nazlı O. Squamous Cell Carcinoma of The Skin Mimicking Breast Cancer: A Case Report. MMJ. 2022;9:304–308.
MLA
Türkkan, Görkem, et al. “Squamous Cell Carcinoma of The Skin Mimicking Breast Cancer: A Case Report”. Medical Journal of Mugla Sitki Kocman University, vol. 9, no. 3, Dec. 2022, pp. 304-8, doi:10.47572/muskutd.978712.
Vancouver
1.Görkem Türkkan, Furkan Gözübüyük, Kutluhan Çınbay, Emine Erva Özen, Fatih Özdemir, Ali Alkan, Melek Ünçel, Ferda Bacakszılar Sarı, Leyla Tekin, Funda Dinç Elibol, Özcan Dere, Gülnihan Eren Kupık, Özgür Tanrıverdi, Okay Nazlı. Squamous Cell Carcinoma of The Skin Mimicking Breast Cancer: A Case Report. MMJ. 2022 Dec. 1;9(3):304-8. doi:10.47572/muskutd.978712