Böbreğin Metastatik Tümörlerinin Literatür Eşliğinde Gözden Geçirilmesi: Tek Merkez Deneyimi

Year 2024, Volume: 19 Issue: 3, 110 - 114, 30.10.2024

Ganime Çoban , Özlem Toluk , Abdullah İlktaç

https://doi.org/10.33719/nju1518955

Abstract

Objective: Böbreğin metastatik tümörleri oldukça nadir olup, bu çalışmada olgularımızın klinikopatolojik verilerini literatür ile tartışıp, farkındalığı artırmayı amaçaladık.
Methods: Trucut biyopsi veya rezeksiyon yapılan toplam 760 olgu incelendi. Olguların primer tanıları, klinik ve histopatolojik özellikleri araştırıldı.
Results: Çalışmada 60 trucut ve 700 parsiyel/radikal nefrektomi yapılan olgu dahil edilmiş olup, 24 olguda böbreğe metastaz saptandı. En sık görülen primer organ akciğer olup, daha az oranda, lenf nodu ve deri, meme, nazal sinüs, safra kesesi, plevra, prostat, kolon, özofagus, mide ve over mevcuttu. Tümörlerin çoğu epitelyal kökenliydi. Olguların çoğu soliter ve endofitik görünümdeydi. Olguların böbrek metastazı, primer tanıdan median 36(2-123) ay sonra olmuştu. Böbrek metastazından sonra median yaşam süresi 8(1-90) aydı.
Conclusion: Bu çalışmada böbreğe metastaz yapan olguların detaylı demografik ve patolojik verileri dökümante edildi. Her ne kadar böbrekte metastatik tümör oranı az da olsa, soliter ve endofitik görünümde bile, özellikle ileri yaştaki olgularda metastaz varlığı akla gelmeli ve histopatolojik bulgular ile konfirme edilmelidir.

Keywords

metastaz, böbrek, prognoz

A Review of Metastatic Tumours of the Kidney with Literature: A Single Centre Experience

Abstract

Objective: Metastatic tumors of the kidney are quite rare. In this study, we aimed to increase awareness by discussing the clinicopathological data of our cases in the context of the literature.
Materials and Methods: A total of 760 cases, subjected to trucut biopsy or resection, were examined. The primary diagnoses, clinical, and histopathological features of the cases were investigated.
Results: The study included 60 trucut and 700 partial/radical nephrectomy cases, with metastasis to the kidney detected in 24 cases. The most common primary organ was the lung, with less frequent cases from lymph nodes, skin, breast, nasal sinus, gall bladder, pleura, prostate, colon, esophagus, stomach, and ovary. Most tumors were of epithelial origin. The majority of the cases were solitary and endophytic in appearance. Kidney metastasis occurred at a median of 36 (2-123) months after the primary diagnosis. The median survival time after kidney metastasis was 8 (1-90) months.
Conclusion: In this study, detailed demographic and pathological data of cases metastasizing to the kidney were documented. Although the rate of metastatic tumors in the kidney is low, even in solitary and endophytic appearances, the possibility of metastasis should be considered, especially in elderly patients, and confirmed with histopathological findings.

Keywords

metastasis,, kidney, prognosis, lung

Ethical Statement

This retrospective study was approved by Bezmialem Vakıf Unıversıty Rectorate Technology Transfer Office Ethics Committees Unit. Protocol: Decision No: 333, Date: 22.11.2023.

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