Effect Of Stress And Cimetidine Therapy On Serum Creatinine And Blood Urea Nitrogen Levels

Y. Kesim; M. Alvur; Y. Alvur; S. Çelik

Research Article

Effect Of Stress And Cimetidine Therapy On Serum Creatinine And Blood Urea Nitrogen Levels

Year 1991, Volume: 8 Issue: 4, 343 - 348, 22.12.2009

Abstract

Experiments were carried out on 140 Swiss-Albino rats. Ten rats were appplied stress and this group was called stress group and the other ten rats were chosen as the control group. Cimetidine were given to 60 rats and physiological salina to the other 60 rats.
The average serum creatinin levels was found to be 0.4710.04 mg/dl, in the nonstressgroup and 0.40+0.04 mg/dl in the stress group. The mean level of boold urea nitrogen (BUN) was found to be 5.0+0.4 mg/dl'in the group that was not applied stress and 4.9±0.5 mg/dl'in the stress group. It was found stress was not veiy efeective on serum creatinine and BUN levels (p>0.05).
The differences on serum creatine and BUN levels between control and experimental group, 1,2,3,7,14 and 21 days after cimetidine therapy, were insignificant (p>0.05).
In according to our results; stress and cimetidine therapy were not effective on the average serum levels of creatinine and BUN.

Keywords

Stress, cimetidine, serum creatinine, blood urea nitrogen.

Effect Of Stress And Cimetidine Therapy On Serum Creatinine And Blood Urea Nitrogen Levels

Year 1991, Volume: 8 Issue: 4, 343 - 348, 22.12.2009

Y. Kesim M. Alvur Y. Alvur S. Çelik

Abstract

Deneyler 140 erkek sıçan üzerinde yapıldı. 10 sıçana stres uygulandı. 10 sıçan kontrol grubu olarak alındı, 60 sıçana stresden sonra simetidin, diğer 60 sıçana da serum fizyolojik verildi. Stres uygulanmayan grupta ortalama serum kreatinin düzeyleri 0.47+0.04mg/dl, stresli grupta 0.4010.04mg/dl olarak bulundu. Kan üre azotu (BUN) düzeyleri stressiz grupta ortalama 5,0±0,4mg/dl, stresli grupta 4,9+0.5mg/dl idi. Stresin serum kreatinin ve BUN düzeylerine önemli bir etkisi olmadığı gözlendi (p>0.05). Simetidin tedavisinin 1,2,3,7,14 ve 21. günleri serum kreatinin ve BUN düzeyleri kontrol grubuna göre istatistiki yönden önemli değildi (P>0.05). Sonuçlarımız stres ve simetidin tedavisinin serum kreatinin ve BUN seviyelerine etkisi olmadığını gösterdi. Anahtar Kelimeler:

Keywords

Stres, Simetidin, Serum kreatinin, BUN.

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Details

Primary Language	English
Subjects	Health Care Administration
Journal Section	Basic Medical Sciences
Authors	Y. Kesim This is me M. Alvur This is me Y. Alvur This is me S. Çelik This is me
Publication Date	December 22, 2009
Submission Date	November 19, 2009
Published in Issue	Year 1991 Volume: 8 Issue: 4

Cite

APA	Kesim, Y., Alvur, M., Alvur, Y., Çelik, S. (2009). Effect Of Stress And Cimetidine Therapy On Serum Creatinine And Blood Urea Nitrogen Levels. Journal of Experimental and Clinical Medicine, 8(4), 343-348.
AMA	Kesim Y, Alvur M, Alvur Y, Çelik S. Effect Of Stress And Cimetidine Therapy On Serum Creatinine And Blood Urea Nitrogen Levels. J. Exp. Clin. Med. December 2009;8(4):343-348.
Chicago	Kesim, Y., M. Alvur, Y. Alvur, and S. Çelik. “Effect Of Stress And Cimetidine Therapy On Serum Creatinine And Blood Urea Nitrogen Levels”. Journal of Experimental and Clinical Medicine 8, no. 4 (December 2009): 343-48.
EndNote	Kesim Y, Alvur M, Alvur Y, Çelik S (December 1, 2009) Effect Of Stress And Cimetidine Therapy On Serum Creatinine And Blood Urea Nitrogen Levels. Journal of Experimental and Clinical Medicine 8 4 343–348.
IEEE	Y. Kesim, M. Alvur, Y. Alvur, and S. Çelik, “Effect Of Stress And Cimetidine Therapy On Serum Creatinine And Blood Urea Nitrogen Levels”, J. Exp. Clin. Med., vol. 8, no. 4, pp. 343–348, 2009.
ISNAD	Kesim, Y. et al. “Effect Of Stress And Cimetidine Therapy On Serum Creatinine And Blood Urea Nitrogen Levels”. Journal of Experimental and Clinical Medicine 8/4 (December 2009), 343-348.
JAMA	Kesim Y, Alvur M, Alvur Y, Çelik S. Effect Of Stress And Cimetidine Therapy On Serum Creatinine And Blood Urea Nitrogen Levels. J. Exp. Clin. Med. 2009;8:343–348.
MLA	Kesim, Y. et al. “Effect Of Stress And Cimetidine Therapy On Serum Creatinine And Blood Urea Nitrogen Levels”. Journal of Experimental and Clinical Medicine, vol. 8, no. 4, 2009, pp. 343-8.
Vancouver	Kesim Y, Alvur M, Alvur Y, Çelik S. Effect Of Stress And Cimetidine Therapy On Serum Creatinine And Blood Urea Nitrogen Levels. J. Exp. Clin. Med. 2009;8(4):343-8.