Istanbul Medipol Ünivesitesi
Bap 2016/18
In this study, the cytotoxic effects of the extracts of methanol: water (80:20)
prepared from the above-ground parts of the varieties of Onobrychis albiflora
Hub.-Mor., Onobrychis argyrea Boiss. subsp. argyrea, Onobrychis galegifolia
Boiss. and Onobrychis tournefortii (Willd.) Desv. species to HCT-116 cells
were investigated. With cytotoxicity analysis that with these species inhibitor
concentrations (IC50) which resulted in a 50% reduction in the proliferation of
HCT-116 cells were identified. In continuation of the study; the antiproliferative
and apoptotic effects of Onobrychis albiflora extract on HCT-116 cells were
evaluated by Caspase 3, Annexin V / PI Apoptosis / Necrosis analysis, Apopxin
Green and 7-AAD Apoptosis / Necrosis analysis. The antiproliferative, apop-
totic and necrotic effects of Onobrychis albiflora extract on HCT-116 cells also
were determined.
Bap 2016/18
Birincil Dil | İngilizce |
---|---|
Konular | Sağlık Kurumları Yönetimi |
Bölüm | Experimental Research |
Yazarlar | |
Proje Numarası | Bap 2016/18 |
Yayımlanma Tarihi | 18 Kasım 2019 |
Gönderilme Tarihi | 26 Ağustos 2019 |
Kabul Tarihi | 24 Eylül 2019 |
Yayımlandığı Sayı | Yıl 2018 Cilt: 35 Sayı: 4 |
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