Reviewing Phlomis rigida Labill From Turkey as a Antimicrobial Efficacy

Yıl 2020, , 1265 - 1271, 01.12.2020

Pınar Erecevit Sönmez , Sevda Kırbag , Uğur Çakılcıoğlu

https://doi.org/10.16984/saufenbilder.769854

Cited By: 4

Öz

This work researched the inhibitory properties of the extract of Phlomis rigida Labill plant including chloroform on gram-negative and positive bacteria, yeasts and dermatophyta; the related plant is used for therapeutic purpose in public. For the disk diffusion method, this extract is effective on Pseudomonas aeruginosa that is one of the negative bacterias by 11.33 ± 0.57 mm inhibition areas. Regarding other bacterias, the effect of the related extract is so low in avoiding the improvement of Escherichia coli, Staphylococcus aureus and Bacillus megaterium by 8.33 ± 0.57 mm inhibition area. It has highly effective on Trichopyton sp. and Candida albicans that are from dermatophytes fungis and yeast by 16.33 ± 0.57 mm inhibition area. About yeast and dermatophytes fungi it has a remarkable impact on Candida glabrata (14.33 ± 0.57 mm inhibition area), Epidermophyton sp. (12.33 ± 0.57 mm inhibition area). Antimicrobial activity of this natural extract against all the microorganisms that were tested by MIC method by concentrations vary by 100 uL and 6.25 uL. Acording to this; the results showed good inhibitory effect with 6.25 μL for C. albicans, Trichophyton sp. with 12.25 μL for C. glabrata. In the other hand it is effective with 25 μL for P. aeruginosa, Epidermophyton sp. with 50 μL for E. coli, S. aureus, B. megaterium. Being used plants for medical purposes as from since the early ages show that these plants can be used as alternatives of available antibiotics; including important medical components is the other reason for being an alternative at the same time. Concerning results, P. rigida can be utilized as a therapeutic drug for the healing of infections caused by microorganisms. In this study, we believe that the P. rigida is important in the search for new antibiotics and will contribute to the literatüre and the world of drug as it affects different types of microorganisms at the lowest level for the first time.

Anahtar Kelimeler

Phlomis rigida Labill, therapeutic medicine, dermatophyta, bacteria, yeast

Proje Numarası

Yok

Kaynakça

• E. M. Altuner and I. Akata, “Antimicrobial activity of some macrofungi extracts,” Sakarya Üniversitesi Fen Bilimleri Dergisi, vol. 14, no.1, pp. 45-49, 2010.
• F. Demirci, K. Guven, B. Demirci, M. Y. Dadandi, and K. H. C. Baser, “Antibacterial activity of two Phlomis essential oils against food pathogens,” Food Control, vol. 19, pp. 1159–1164, 2008.
• Y. Akgül, “Antibacterial activities of some plant extracts against Pseudomonas aeruginosa and K. pneumoniae isolates causing ürinary tract infection (M. Sc.), İdrar yolu enfeksiyonlarına neden olan Pseudomonas aeruginosa ve Klebsiella pneumoniae izolatlarına karşı bazı bitki ekstraktlarının antibakteriyal aktiviteleri,” Yüsek Lisans Tezi, Nevşehir Hacı Bektaş Veli Üniversitesi Fen Bilimleri Enstitüsü, Nevşehir, pp. 75, 2014.
• [I. Limem-Ben Amor, J. Boubaker, M. B. Sgaier, I. Skandrani, W. Bhouri, A. Neffati, S. Kilani, I. Bouhlel, K. Ghedira, and L. Chekir-Ghedira, “Phytochemistry and biological activities of Phlomis species,” Journal of Ethnopharmacology, vol. 125, pp. 183–202, 2009.
• Z. Ulukanlı and A. Akkaya, “Antibacterial activities of Marrubium catariifolium and Phlomis pungens var. Hirta grown wild in eastern Anatolia, Turkey,” Internatioanal Journal of Agriculture & Biology, pp. 1560–8530, 2011.
• S. Toroğlu and M. Çenet, “Comparsion of antimicrobial activities of essential oil and solvent extracts of endemic Phlomis oppositiflora Boiss. & Hausskn. From Turkey,” Pakistan Journal of Zoology, vol. 45, pp. 475-482, 2013.
• Y. Takeda, H. Matsumura, T. Masuda, G. Honda, H. Otsuka, Y. Takaishi, and E. Sezik, “Phlorigidosides A–C, iridoid glucosides from Phlomis rigida,” Phytochemistry, vol. 53, pp. 931–935, 2000.
• I. Kyriakopoulou, P. Magiatis, A. L. Skaltsounis, N. Aligiannis, and C. Harvala, “Samioside, a new phenylethanoid gycoside with free-radical scavenging and antimicrobial activities from Phlomis samia,” Journal of Natural Products, vol. 64, pp. 1095-7, 2001.
• A. E. Karadağ, A. E. Demirci, B. Kültür, Ş. F. Demirci, and K. H. C. Başer, “Antimicrobial, anticholinesterase evaluation and chemical characterization of essential oil Phlomis kurdica Rech. fil. Growing in Turkey,” Journal of Essential Oil Research, vol. 32, pp. 242-246, 2020.
• T. Y. Shin and J. K. Lee, “Effect of Phlomis umbrosa root on mastcell-dependent immediate-type allergic reactions by anal therapy,” Immunopharmacology and Immunotoxicology, vol. 25, pp. 73-85, 2003.
• E. Souri, G. Amin, A. Dehmobed-Sharifabadi, A. Nazifi, and H. Farsam, “Antioxidative activity of sixty plants from Iran,” Iranian Journal of Pharmaceutical Research, vol. 3, pp. 55-59, 2004.
• M. M. Balos and H. Akan, “Zeytinbahçe -Akargay (Birecik, Şanliurfa) arasında kalan bölgenin etnobotanik özellikleri,” Selçuk Üniversitesi Fen Fakültesi Fen Dergisi, vol. 29, pp. 155- 171, 2007.
• M. A. Khalilzadeh, M. Tajbakhsh, A. Rineh, “Study of the essential oils composition of leaves and flowers of two subspecies Phlomis herba-Venti (Pungens And Lenkoranica) from Iran,” Journal of Essential Oil Research, vol. 20, pp. 46–48, 2008.
• P. H. Davis “Flora of turkey and the aegean islands,” England: Edinburgh Univ. Press, vol. 7, 8, 9, 1970-1984-1985.
• C. H. Collins and P. M. Lyne “Microbiological methods,” London: Butter worths & Co. (Publishers) Ltd, pp. 410, 1989.
• P. Erecevit, and S. Kırbağ, “Antimicrobial activity of some plant species used for the medical purpose in Turkey,” The Journal of Phytopharmacology, vol. 6, pp. 93-97, 2017.
• B. Dülger, “Coriolus versicolor (L. ex Fr.) Quel. makrofungusunun antimikrobiyal aktivitesi,”Uludağ Turkısh Journal of Biology, vol. 23, pp. 385–392, 1999.
• K. Hürkan, M. Ballı Yüksel, Y. Kemeç Hürkan, and N. Demir, “Bazı salep orkidelerinin antioksidan ve antimikrobiyal özellikleri,” 2019 UMTEB 6. Uluslararası Mesleki ve Teknik Bilimler Bilimler Kongresi, pp. 29, 2019.
• M. Nikan, S. Saeidnia, A. Manayi, and S. Saadatmand, “Essential oils of four Phlomis species growing in Iran: chemical composition, antimicrobial and antifungal activity,” Progress in Nutrition, vol. 19, pp. 75-79, 2017.
• E. Kulani, M. Kazemi, and M. Dakhili, “Chemical composition and biological activities of Phlomis rigida Labill essential oil,” 2nd National Congress on Medicinal Plants 15-16 May, Tehran, Iran, p. 291. 2013.
• M. D. Ristic, S. Duletic-Lausevic, J. Knezevic-Vukcevic, P. D. Marin, D. Simic, Vukojevic, P. Janackovic, and V. Vajs, “Antimicrobial activity of essential oils and ethanol extract of Phlomis fruticosa L. (Lamiaceae),” Phytotherapy Research,” vol. 14, pp. 267–271, 2000.
• N. Aligiannis, E. Kalpoutzakis, I. Kyriakopoulou, S. Mitaku, and I. B. Chinou, “Essential oils of Phlomis species growing in Greece: chemical composition and antimicrobial activity,” Flavour and Fragrance Journal, vol. 19, pp. 320–324, 2004.
• K. Morteza-Semnani, M. Saeedi, M. R. Mahdavi, F. Rahimi, “Antimicrobial studies on extracts of three species of Phlomis,” Pharmaceutical Biology,” vol. 44, pp. 426–429, 2006.
• M. D. C. Zinsou, F. Assogba, F. Gbaguidi, and M. Moudachirou, “Chemical composition and in vitro investigation of biological activities of Hemizygia bracteosa (Benth.) Briq leaves,” Journal of Pharmacognosy and Phytotherapy, vol. 10, pp. 11-20, 2018.