The investigation of the reactions of some pyrazole-3-carboxylic acids with various diamines and diols

Yıl 2012, Cilt: 16 Sayı: 1, 47 - 52, 01.06.2012

Rahmi Kasımoğulları Makbule Maden Samet Mert

Öz

-

Anahtar Kelimeler

pyrazole-3-carboxylic acid, bis-carboxamide, ester, diamine, diol

Bazı pirazol-3-karboksilik asitlerin çeşitli diamin ve diollerle reaksiyonlarının incelenmesi

Öz

In this study, some new derivatives were synthesized of 4-benzoyl-1-(3-nitrophenyl)-5-phenyl-1H-pyrazole-3-carboxylic acid (1) and 4-(ethoxycarbonyl)-1-(3-nitrophenyl)-5-phenyl-1H-pyrazole-3-carboxylic acid (2) that they were pyrazole carboxylic acid derivatives. Firstly, 1 and 2 reacted with SOCl2 to transform them into acyl chlorides (3, 4). Then various bis-carboxamide derivatives (58) were obtained from the reaction of 3 and 4 with various diamines and also a β-hydroxy ester (9) derivative was obtained from the reaction of 3 with ethylene glycol. The structures of synthesized compounds were elucidated with using FT-IR, 1H NMR, 13C NMR and elemental analysis methods.

Anahtar Kelimeler

pirazol-3-karboksilik asit, bis-karboksamit, ester, diamin, diol

Kaynakça

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