Sinnamaldehitin yeni schiff bazlarının sentezi ve antioksidan özelliklerinin incelenmesi

Yıl 2018, Cilt: 22 Sayı: 3, 1024 - 1032, 01.06.2018

Belma Zengin Kurt

https://doi.org/10.16984/saufenbilder.356603

Cited By: 1

Öz

Bu çalışmada, sinnamaldehitin 9
yeni schiff bazı sentezlenmiş ve bu bileşiklerin 2,2-difenil-1-pikrilhidrazil radikal söndürücü kapasitesi
(DPPH), Troloks eşdeğeri antioksidan
kapasitesi (ABTS) ve bakır (II)
iyonu indirgeyici antioksidan kapasitesi (CUPRAC) olmak üzere üç farklı
yöntemle antioksidan aktivite özellikleri incelenmiştir. Bu bileşiklerin içinde
(2,3-dihidroksibenziliden)amino)fenil)-5-fenilpenta-2,4-dien-1-on
(4c) bileşiği her üç yönteme göre oldukça etkin bir şekilde antioksidan
özellik göstermiştir. Ayrıca sentezlenen bileşiklerin yapı aktivite ilişkisi
incelenerek bileşiklerin sahip oldukları grupların antioksidan aktiviteyi hangi
yönde etkilediği ortaya konulmuştur.

Anahtar Kelimeler

Sinnamaldehit, Schiff bazı, Antioksidan aktivite

Synthesis and antioxidant activities of new schiff bases of Cinnamaldehyde

Öz

In this study, 9 new schiff bases of
cinnamaldehyde were synthesized and their antioxidant activities were examined
by DPPH, ABTS and CUPRAC. Among the synthesized compounds,
(2,3-dihydroxybenzylidene)amino)phenyl)-5-phenylpenta-2,4-dien-1-one (4c)
showed high effective antioxidant activity for all three methods. In addition,
the structure activity relationship of the synthesized compounds was examined,
and it was revealed how the groups possessed by the compounds had an effect on
antioxidant activity.

Anahtar Kelimeler

Cinnamaldehyde, Schiff base, Antioxidant activity

Kaynakça

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