Abstract
SüleymanDemirel Üniversitesi
TIP FAKÜLTESİ DERGİSİ: 2007 Haziran; 14(2)
Subkortikal bant heterotopisi - olgu sunumu
Betül Zantur*, M. Cem Dönmez**, Serpil Demirci**
*Niğde Devlet Hastanesi,
**Süleyman Demirel Üniversitesi, Tıp Fakültesi, Nöroloji AD
Özet
Heterotopi sınırlı veya yaygın bir nöronal migrasyon bozukluğudur. Klinikte hafif mental retardasyon, epileptik nöbetler, psikiyatrik belirtiler veya sistemik bozukluklarla seyredebilir. Epileptik nöbetler olguların yaklaşık %90'ında gözlenir ve genellikle tedaviye dirençlidir. Heterotopinin klinik belirti ve bulguları erişkin yaşa kadar herhangi bir dönemde görülebilir. Bu yazıda epileptik nöbet ve hemiparezi ile seyreden ve monoterapi ile nöbetlerin oldukça iyi bir şekilde kontrol edildiği bir heterotopi olgusu sunulmaktadır.
Anahtar kelimeler: nöronal migrasyon, heterotopi, epilepsi, hemiparezi
Abstract
Subcortical band heterotopia- case report
Heterotopia is a localized or diffuse neuronal migration disorder. Clinically it may be associated with mental retardation, epileptic seizures, psychiatric symptoms or systemic disorders. Epileptic seizures are seen in about 90% of cases and are usually resistant to treatment. The disorder may present itself at any age, up to adulthood. In this paper, we report a case of heterotopia presenting with epileptic seizures and hemiparesis in which seizures were fairly well controlled with monotherapy.
Key words: neuronal migration, heterotopia, epilepsy, hemiparesis
Keywords
References
- Gleeson JG. Neuronal migration disorders. Ment Retard Dev Disabil Res Rev 2001;7: 167-71
- Dubeau F, Tampieri D, Lee N, et al. Periventicular and subcortical nodular heterotopia. A study of 33 patients. Brain 1995;118:1273-87
- Sarnat HB. Cerebral dysgenesis: embriology and clinical expression. New York, Oxford University Pres,1992;473-79
- Falconer J, Wada J, Martin W, Li D. PET, CT, and MRI imaging of neuronal migration anomalies in epileptic patients. Can J Neurol Sci 1990;17: 35-9
- Barkovich AJ, Kjos BO. Gray matter heterotopias: MR characteristics and correlation with developmental and neurologic manifestations. Radiology 1992;182: 493-9
- Munari C, Francione S, Kahane P, et al. Usefulness of stereo EEG investigations in partial epilepsy associated with cortical dysplastic lesions and grey matter heterotopia. In : Guerrin R, Andermann F, Canapicchi R, Roger J, Zifkin B, Pfanner P. Dysplasis of Cerebral Cortex and Epilepsy. Philadelphia, Lippincott, 1996;383-94
- Huttenlocher PR, Taravath S, Mojtahedi S. Periventricular heterotopia and epilepsy. Neurology 1994;44: 51-5
- Cho WH, Seidenwurm D, Barkovich AJ. Adult- onset neurologic dysfunction associated with cortical malformations. Am J Neuroradiol 1999;20:1037-43
Abstract
References
- Gleeson JG. Neuronal migration disorders. Ment Retard Dev Disabil Res Rev 2001;7: 167-71
- Dubeau F, Tampieri D, Lee N, et al. Periventicular and subcortical nodular heterotopia. A study of 33 patients. Brain 1995;118:1273-87
- Sarnat HB. Cerebral dysgenesis: embriology and clinical expression. New York, Oxford University Pres,1992;473-79
- Falconer J, Wada J, Martin W, Li D. PET, CT, and MRI imaging of neuronal migration anomalies in epileptic patients. Can J Neurol Sci 1990;17: 35-9
- Barkovich AJ, Kjos BO. Gray matter heterotopias: MR characteristics and correlation with developmental and neurologic manifestations. Radiology 1992;182: 493-9
- Munari C, Francione S, Kahane P, et al. Usefulness of stereo EEG investigations in partial epilepsy associated with cortical dysplastic lesions and grey matter heterotopia. In : Guerrin R, Andermann F, Canapicchi R, Roger J, Zifkin B, Pfanner P. Dysplasis of Cerebral Cortex and Epilepsy. Philadelphia, Lippincott, 1996;383-94
- Huttenlocher PR, Taravath S, Mojtahedi S. Periventricular heterotopia and epilepsy. Neurology 1994;44: 51-5
- Cho WH, Seidenwurm D, Barkovich AJ. Adult- onset neurologic dysfunction associated with cortical malformations. Am J Neuroradiol 1999;20:1037-43
Details
| Primary Language | English |
|---|---|
| Journal Section | Case Reports |
| Authors | |
| Publication Date | April 30, 2009 |
| Submission Date | April 30, 2009 |
| Published in Issue | Year 2007 Volume: 14 Issue: 2 |
Süleyman Demirel Üniversitesi Tıp Fakültesi Dergisi/Medical Journal of Süleyman Demirel University is licensed under Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International.