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Hypomelanosis of Ito and Hemimegalencephaly

Year 2009, Volume: 16 Issue: 2, 23 - 26, 30.06.2009

A.Barış Akcan Nihal Olgaç Dündar Seyhan Oygucu Şenay Haspolat Nihal Oygür

Abstract

Hypomelanosis of Ito is characterized by unilateral or bilateral macular hypopigmented whorls, streaks, and patches. Abnormalities of the eyes, musculoskeletal system, and central nervous system may also be present. Hemimegalencephaly is a congenital brain malformation characterized by unilateral enlargement of the cerebral hemisphere. Hemimegalencephaly is an often isolated finding, but it has been described as an occasional feature of a large number of syndromes. We report a case of Hypomelanosis of Ito associated with hemimegalencephaly

Keywords

Hypomelanosis of Ito hemimegalencephaly newborn

References

  • Ito M. Studies on melanin XI. Incontinentia pigmenti achromians. A singular case of nevus depigmentosus systematicus bilateralis. Tohoku J Exp Med 1952; 55: 57-59.
  • Kuster W, Konig A. Hypomelanosis of Ito: No entity, but a cutaneous sign of mosaicism. Am J Med Genet 1999; 85: 346-350.
  • Mosher DB, Fitzpatrick TB, Hori Y, Ortonne J-P. Disorders of Pigmentation. In Fitzpatrick TB, Eissen AZ, Wolff K, Freedberg IM, Austen KF (Eds.). Dermatology In General Medicine. Mc Graw-Hýll Inc. Newyork 1993; 946.
  • Ruiz MR, Toussaint S, Tamayo L, Laterza A, del Castillo V. Hypomelanosis of Ito: diagnostic criteria and report of 41 cases. Pediatr Dermatol 1992; 9: 1- 10.
  • Serdal G, Dilek Y, Meral T. Kortikal geliþimsel malformasyonlar. Çocuk Saðlýðý ve Hastalýklarý Dergisi 2007; 50: 210-225.
  • Barkovich AJ. Congenital malformations of the brain and skull. In: Barkovich AJ, editor. Pediatric Neuroimaging,second ed. Philadelphia: Lippincott Raven, 1996: 225-230.
  • Sarnat LF. Hemimegalencephaly: Part 1. Genetic, clinical, and imaging aspects. J Child Neurol 2002; 17: 373-384.
  • Sarnat LF, Sarnat HB. Hemimegalencephaly. In: Barth PG(ed). Disorders of Neuronal Migrations, (1st ed). London: Mac Keith Pres; 2003: 104-126.
  • Sasaki M, Hashimoto T, Furushima W, Okada M, Kinoshita S, Fujikawa Y et al. Clinical Aspects of Hemimegalencephaly by means of a Nationwide Survey. Child Neurol 2005; 20: 337-341.
  • Battistella PA, Peserico A, Bertoli P, Drigo P, Laverda AM, Casara GL.
  • Hypomelanosis of Ito and hemimegalencephaly. Childs Nerv Syst 1990; 6: 421-423.
  • Bhushan V, Gupta RR, Weinreb J, Kairam R. Unusual brain MRI findings in a patient with hypomelanosis of Ito. Pediatr Radiol 1989;20: 104-106.
  • Peserico A, Battistella PA, Bertoli P, Drigo P. Unilateral hypomelanosis of Ito with hemimegalencephaly. Acta Paediatr Scand 1988;77: 446-447.
  • Tagawa T, Futagi Y, Arai H, Mushiake S, Nakayama M. Hypomelanosis of Ito assosiated with hemimegalencephaly: a clinicopathological study. Pediatr Neurol 1997;17: 180-184.
  • Ruggieri M, Pavone L. Hypomelanosis of Ito: clinical syndrome or just phenotype. J Child Neurol 2000; 15: 635-44.
  • Pascual-Castroviejo I, Lopez-Rodriguez L, de la Cruz Medina M, Salamanca-maesso C, Roche Herrero C. Hypomelanosýs of Ito. Neurological complications in 34 cases. Can J Neurol Sci 1988; 15: 124-129.
  • Amon M, Menapace R, Kirnbauer R . Ocular symptomatology in familial hypomelanosis Ito: Incontinentia pigmenti achromians.Ophthalmologica 1990; 200:1-6.
  • Sybert VP. Hypomelanosis of Ito: a description, not a diagnosis. J Invest Dermatol 1994; 103: 141-143.
  • Shobha N, Taly AB, Sinha S, Arunodaya GR, Srikanth SG. Hypomelanosis of Ito. J Neurol Neurosurg Psychiatry 2006;77: 873.
  • Glover MT, Brett EM, Atherton DJ. Hypomelanosis of Ito. Spectrum of the disease. J Pediatr 1989; 115: 75-80.
  • Steiner J, Adamsbaum C, Desguerres I, Lalande G, Raynaud F, Pansot G, et al. Hypomelanosis of Ito and brain abnormalities: MRI findings and literature review.
  • Pediatr Radiol 1996; 26: 763-768.
  • Kuzniecky RI, Barkowich AJ. Malformations of cortical development and epilepsy. Brain Dev 2001; 23: 2-11.

Ýto hipomelanozis ve hemimegalensefali birlikteliði

Year 2009, Volume: 16 Issue: 2, 23 - 26, 30.06.2009

A.Barış Akcan Nihal Olgaç Dündar Seyhan Oygucu Şenay Haspolat Nihal Oygür

Abstract

Ito hipomelanozu, tek veya çift taraflý maküler hipopigmente sarmal þekiller, çizgiler ve yamalarla karakterize bir antitedir. Beraberinde gözlerin, kas iskelet sisteminin ve santral sinir sisteminin anormallikleri bulunabilir. Hemimegalensefali, bir serebral hemisferin tek taraflý büyümesiyle karakterize konjenital beyin malformasyonudur. Hemimegalensefali, genelde izole bir bulgu olmasýna raðmen, birçok sendromla da birlikte tarif edilebilir. Ito Hipomelanozu ve hemimegalensefali birlikteliðini gösteren bir olguyu sunmaktayýz.

Keywords

Ito Hipomelanozu hemimegalensefali yenidoðan

References

  • Ito M. Studies on melanin XI. Incontinentia pigmenti achromians. A singular case of nevus depigmentosus systematicus bilateralis. Tohoku J Exp Med 1952; 55: 57-59.
  • Kuster W, Konig A. Hypomelanosis of Ito: No entity, but a cutaneous sign of mosaicism. Am J Med Genet 1999; 85: 346-350.
  • Mosher DB, Fitzpatrick TB, Hori Y, Ortonne J-P. Disorders of Pigmentation. In Fitzpatrick TB, Eissen AZ, Wolff K, Freedberg IM, Austen KF (Eds.). Dermatology In General Medicine. Mc Graw-Hýll Inc. Newyork 1993; 946.
  • Ruiz MR, Toussaint S, Tamayo L, Laterza A, del Castillo V. Hypomelanosis of Ito: diagnostic criteria and report of 41 cases. Pediatr Dermatol 1992; 9: 1- 10.
  • Serdal G, Dilek Y, Meral T. Kortikal geliþimsel malformasyonlar. Çocuk Saðlýðý ve Hastalýklarý Dergisi 2007; 50: 210-225.
  • Barkovich AJ. Congenital malformations of the brain and skull. In: Barkovich AJ, editor. Pediatric Neuroimaging,second ed. Philadelphia: Lippincott Raven, 1996: 225-230.
  • Sarnat LF. Hemimegalencephaly: Part 1. Genetic, clinical, and imaging aspects. J Child Neurol 2002; 17: 373-384.
  • Sarnat LF, Sarnat HB. Hemimegalencephaly. In: Barth PG(ed). Disorders of Neuronal Migrations, (1st ed). London: Mac Keith Pres; 2003: 104-126.
  • Sasaki M, Hashimoto T, Furushima W, Okada M, Kinoshita S, Fujikawa Y et al. Clinical Aspects of Hemimegalencephaly by means of a Nationwide Survey. Child Neurol 2005; 20: 337-341.
  • Battistella PA, Peserico A, Bertoli P, Drigo P, Laverda AM, Casara GL.
  • Hypomelanosis of Ito and hemimegalencephaly. Childs Nerv Syst 1990; 6: 421-423.
  • Bhushan V, Gupta RR, Weinreb J, Kairam R. Unusual brain MRI findings in a patient with hypomelanosis of Ito. Pediatr Radiol 1989;20: 104-106.
  • Peserico A, Battistella PA, Bertoli P, Drigo P. Unilateral hypomelanosis of Ito with hemimegalencephaly. Acta Paediatr Scand 1988;77: 446-447.
  • Tagawa T, Futagi Y, Arai H, Mushiake S, Nakayama M. Hypomelanosis of Ito assosiated with hemimegalencephaly: a clinicopathological study. Pediatr Neurol 1997;17: 180-184.
  • Ruggieri M, Pavone L. Hypomelanosis of Ito: clinical syndrome or just phenotype. J Child Neurol 2000; 15: 635-44.
  • Pascual-Castroviejo I, Lopez-Rodriguez L, de la Cruz Medina M, Salamanca-maesso C, Roche Herrero C. Hypomelanosýs of Ito. Neurological complications in 34 cases. Can J Neurol Sci 1988; 15: 124-129.
  • Amon M, Menapace R, Kirnbauer R . Ocular symptomatology in familial hypomelanosis Ito: Incontinentia pigmenti achromians.Ophthalmologica 1990; 200:1-6.
  • Sybert VP. Hypomelanosis of Ito: a description, not a diagnosis. J Invest Dermatol 1994; 103: 141-143.
  • Shobha N, Taly AB, Sinha S, Arunodaya GR, Srikanth SG. Hypomelanosis of Ito. J Neurol Neurosurg Psychiatry 2006;77: 873.
  • Glover MT, Brett EM, Atherton DJ. Hypomelanosis of Ito. Spectrum of the disease. J Pediatr 1989; 115: 75-80.
  • Steiner J, Adamsbaum C, Desguerres I, Lalande G, Raynaud F, Pansot G, et al. Hypomelanosis of Ito and brain abnormalities: MRI findings and literature review.
  • Pediatr Radiol 1996; 26: 763-768.
  • Kuzniecky RI, Barkowich AJ. Malformations of cortical development and epilepsy. Brain Dev 2001; 23: 2-11.
There are 23 citations in total.

Details

Primary Language Turkish
Subjects Dentistry
Journal Section Case Reports
Authors

A.Barış Akcan This is me

Nihal Olgaç Dündar This is me

Seyhan Oygucu This is me

Şenay Haspolat This is me

Nihal Oygür This is me

Publication Date June 30, 2009
Submission Date October 30, 2009
Published in Issue Year 2009 Volume: 16 Issue: 2

Cite

Vancouver Akcan A, Olgaç Dündar N, Oygucu S, Haspolat Ş, Oygür N. Ýto hipomelanozis ve hemimegalensefali birlikteliði. Med J SDU. 2009;16(2):23-6.

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