BÖBREĞİN JUKSTAGLOMERÜLER HÜCRELİ TÜMÖRÜ: BİR OLGU SUNUMU

Yıl 2019, Cilt: 26 Sayı: 4, 486 - 489, 01.12.2019

Afife Uğuz Sema Bircan , Şirin Başpınar , Osman Ergün , Murat Demir

https://doi.org/10.17343/sdutfd.491029

Öz

Jukstaglomerüler hücreli tümör (JGHT)
sekonder hiperaldosteronizme bağlı hipertansiyon ve hipokalemiye neden olan
benign renin salgılayan bir tümördür. Genellikle adölesan ve genç erişkinleri
etkiler. Klinik
olarak tümörlerin çoğu benign bir seyir göstermekle birlikte vasküler invazyon
veya metastaz yapan nadir tümörler bildirilmektedir. Burada tekrarlayan baş
ağrıları ve hipertansiyonu olan 19 yaşındaki bir kadın hastada JGHT olgusunu
sunuyoruz.

Anahtar Kelimeler

Jukstaglomerüler hücreli tümör, böbrek

Kaynakça

• 1. Robertson PW, Klidjian A, Harding LK, Walters G, Lee MR, Robb-Smith AH. Hypertension due to a renin-secreting renal tumour. Am J Med. 1967; 43: 963-76.
• 2. Kihara I, Kitamura S, Hoshino T, Seida H, Watanabe T. A hitherto unreported vascular tumor of the kidney: A proposal of "juxtaglomerular cell tumor". Acta Pathol Jpn. 1968; 18: 197-206.
• 3. Kuroda N, Maris S, Monzon FA, Tan PH, Thomas A, Petersson FB, et al. Juxtaglomerular cell tumor: A morphological, immunohistochemical and genetic study of six cases. Hum Pathol. 2013; 44: 47-54.
• 4. Onder S, Baydar DE. A case of juxtaglomerular cell tumor with novel histologic features. Int J Surg Pathol. 2011; 19: 65-70.
• 5. Gottardo F, Cesari M, Morra A, Gardiman M, Fassina A, Dal Bianco M. A kidney tumor in an adolescent with severe hypertension and hypokalemia: An uncommon case--case report and review of the literature on reninoma. Urol Int. 2010; 85: 121-4.
• 6. Sakata R, Shimoyamada H, Yanagisawa M, Murakami T, Makiyama K, Nakaigawa N, et al. Nonfunctioning juxtaglomerular cell tumor. Case Rep Pathol. 2013; 2013: 973865.
• 7. Wong L, Hsu TH, Perlroth MG, Hofmann LV, Haynes CM, Katznelson L. Reninoma: Case report and literature review. J Hypertens. 2008; 26: 368-73.
• 8. Kuroda N, Gotoda H, Ohe C, Mikami S, Inoue K, Nagashima Y, et al. Review of juxtaglomerular cell tumor with focus on pathobiological aspect. Diagn Pathol. 2011; 6: 80.
• 9. Kuroda N, Moriki T, Komatsu F, Miyazaki E, Hayashi Y, Naruse K, et al. Adult-onset giant juxtaglomerular cell tumor of the kidney. Pathol Int. 2000; 50: 249-54.
• 10. Kodet R, Taylor M, Vachalova H, Pycha K. Juxtaglomerular cell tumor. an immunohistochemical, electron-microscopic, and in situ hybridization study. Am J Surg Pathol. 1994; 18: 837-42.
• 11. Beaudoin J, Perigny M, Tetu B, Lebel M. A patient with a juxtaglomerular cell tumor with histological vascular invasion. Nat Clin Pract Nephrol. 2008; 4: 458-62.
• 12. Wang F, Shi C, Cui Y, Li C, Tong A. Juxtaglomerular cell tumor: Clinical and immunohistochemical features. J Clin Hypertens (Greenwich). 2017; 19: 807-12.
• 13. Duan X, Bruneval P, Hammadeh R, Fresco R, Eble JN, Clark JI, Vigneswaran WT, Flanigan RC, Pickman MN. Metastatic juxtaglomerular cell tumor in a 52-year old man. Am J Surg Pathol. 2004;28(8):1098–1102.
• 14. Gherardi GJ, Arya S, Hickler RB. Juxtaglomerular body tumor: A rare occult but curable cause of lethal hypertension. Hum Pathol. 1974;5(2):236–240.