BibTex RIS Kaynak Göster

Intermediate Clinical Follow Up Results of Carotid Artery Stenting: Single Center Study

Yıl 2013, , 65 - 71, 01.06.2013
https://doi.org/10.5505/sakaryamj.2013.55265

Öz

ObjectiveCarotid artery stent treatment is developed as an alternative of carotid endarterectomy and it is provided by proving the comparison results of technical success' procedure depending morbidity-mortality and restenoses ratings with carotid endarterectomy by extended researches. We tried to present the mid-term clinic results of stent application by using distal emboli tools which are applied to carotid artery disease patients who are decided to have revascularizationMethods20 carotid artery disease patients who were diagnosed in the survey of Cardiology, Emergency and Neurology policlinics were included to the study in years between 2006-2010. The criteria for inclusion to the study was 60-99 % stenoses of diameter in asymptomatic patients who were assessed angiographically by NASCET method or 70-99 % stenoses of diameter in carotid bifurcation.ResultsAfter reaching every patient by phone, it was determined that; in one patient there was a transient ischemic attack, 48 days after the process (5 %), 3 different patients both had minor bleeding (15 %) and had no need for eritrosit transfusion and in one patient there was acute coronary syndrome /unstabil angina (5 %) but medical treatment was offered. One patient with transient ischemic attack an one patient with minor bleeding after the process; both had one day hospital stay (10 %). ConclusionIn the light of the clinic researches, especially the CREST research, which has the closest parameters to our design and population, we tried to measure the success rates of carotid artery stent treatment of our clinic. We tried to use emboli protecting devices on the patients who were included to the study. At the end of the following process we think that carotid artery stent treatment can be an alternative in the group of high risk surgery patients.

Kaynakça

  • Grau AJ, Weimar C, Buggle F, Heinrich A, Goertler M, Neumaier S, et al. Risk factors, outcome, and treatment in subtypes of ischemic stroke: the German stroke data bank. Stroke 2001;32:2559–2566.
  • ESC Guidelines on the diagnosis and treatment of peripheral artery diseases Document covering atherosclerotic disease of extracranial carotid and vertebral, mesenteric, renal, upper and lower extremity arteries The Task Force on the Diagnosis and Treatment of Peripheral Artery Diseases of the Europen Society of Cardiology (ESC).
  • Grant EG, Benson CB, Moneta GL, Alexandrov AV, Baker JD, Bluth EI, et al. Carotid artery stenosis: gray-scale and Doppler US diagnosis—Society of Radiologists in Ultrasound Consensus Conference. Radiology 2003;229:340–346.
  • Faxon DP, Fuster V, Libby P, Beckman LA, Hiatt WR, Thompson RW, et al. Atherosclerotic vascular disease conference: Writing Group III: pathophysiology. Circulation 2004:109:2617-25.
  • Eckard DA, Zarmov DM, McPherson CM, Siegel EL, Eckard VR, Batnitzky S, et al. Intracranial internal carotid artery angioplasty: technique with clinical and radiographic result and follow-up. AJR 1999;172:703-707.
  • Theron JG, Payelle GG, Coskun O, Huet HF, Guimaraens L. Carotid artery stenosis: treatment with protected balloon angioplasty and stent placement. Radiology 1996;201:627-636.
  • Interventional In: Henry M, Amor M, editors. 9th International course book on Peripheral Vascular Intervention. Europe Bd;1988.p.607-20.
  • 2011 ASA /ACCF /AHA /AANN /AANS /ACR /ASNR /CNS /SAIP /SCAI /SIR / SNIS/SVM/SVS Guideline on the Management of Patients With Extracranial Carotid and Vertebral Artery Disease.
  • Katzen BT, Ardid MI, MacLean AA, Kovacs MF, Zemel G, Benenati JF, et al. Bivalirudin as an anticoagulation agent: safety and efficacy in peripheral interventions. J Vasc Interv Radiol 2005;16:1183–7.
  • Schneider LM, Polena S, Roubin G, Iyer S, Vitek J, Panagopoulos G, et al. Carotid stenting and bivalirudin with and without vascular closure: 3-year analysis of procedural outcomes. Catheter Cardiovasc Interv 2010;75:420–6.
  • Osborn AG. Diagnostic Cerebral Angiography. 2 nd edition. Philadelphia: Lippincott, 1999.
  • Strong JP, Malcom GT, Mc Mahan CA, Tracy RE, Newman WP 3rd, Herderick EE, et al. Prevalence and extent of atherosclerosis in adolescents and young adults. Implication for prevention from the pathobiological determinants of atherosclerosis in youth study. JAMA 1999;281:727-35.
  • McGill HC Jr, McMahan CA, Zieske AW, Tracy RE, Malcom GT, Herderick EE, et al. Association of Coronary Heart Disease Risk Factors with microscopic qualities of coronary atherosclerosis in youth. Circulation 2000;102(4):374-9.
  • Sata M, Saiura A, Kunisato A, Tojo A, Okada S, Tokuhisa T, et al. Hematopoietic stem cells differentiate into vascular cells that participate in the pathogenesis of atherosclerosis. Nat Med 2002;8(4):403-9.
  • O'Brien KD, Olin KL, Alpers CE, Chiu W, Ferguson M, Hudkins K, et al. Comparison of apolipoprotein and proteoglycan deposits in human coronary atherosclerotic plaques: colocalization of biglycan with apolipoproteins. Circulation 1998;98(6):519-27.
  • Wardlaw JM, Chappell FM, Stevenson M, De Nigris E, Thomas S, Gillard J, et al. Accurate, practical and cost-effective assessment of carotid stenosis in the UK. Health Technol Assess 2006;10:iii– iv, ix–x, 1–182.
  • Economopoulos KP, Sergentanis TN, Tsivgoulis G, Mariolis AD, Stefanadis C. Carotid artery stenting versus carotid endarterectomy: a comprehensive meta-analysis of short-term and long-term outcomes. Stroke 2011;42:687–692.

Karotis artere stent yerleştirmenin orta dönem klinik sonuçları.: Tek merkez çalışması

Yıl 2013, , 65 - 71, 01.06.2013
https://doi.org/10.5505/sakaryamj.2013.55265

Öz

AmaçKarotis arter stent (KAS) tedavisi KEA'ye alternatif bir tedavi olarak gelişmiş olup bu gelişim teknik başarının prosedüre bağlı morbidite-mortalite ve restenoz oranlarının KEA ile karşılaştırılması ile elde edilen sonuçların büyük, geniş serilere dayanan çalışmalarla ispatlanması ile sağlanmıştır. Bu çalışmada kliniğimize başvuran ve revaskülarizasyon kararı alınan karotis arter hastalığı tanısı almış hastalarda distal emboli cihazları kullanılarak stent uygulamasının orta dönem klinik sonuçlarını sunmaya çalıştık. YöntemlerÇalışmaya 2006- 2010 yılları arasında Kardiyoloji polikliniği, Acil Servis ve Nöroloji kliniğini takiplerinde karotis arter hastalığı tanısı almış 20 hasta dahil edildi. Çalışmaya dahil edilme kriteri NASCET metodu ile angiografik olarak değerlendirilip asemptomatik hastalarda % 60-99 çap darlığı veya semptomatik hastalarda % 70-99 çap darlığı olan karotis bifurkasyon darlığı idi.BulgularHastaların hepsine telefon ile ulaşıldıktan sonra sorgulanmaları sonucunda 1 hastada işlemden 48 gün sonrasında geçici iskemik atak (%5), 3'ünde farklı hastalar olmak üzere minör kanama öyküsü olduğu (%15) ve eritrosit transfüzyon ihtiyacının olmadığı ve 1 hastada ise akut koroner sendrom/ unstabil anjina olduğu (%5) fakat medikal tedavi önerildiği öğrenildi. Geçici iskemik atak olan ve işlem sonrasında minör kanama öyküsü olan bir hasta olmak üzere 2 hastanın 1 günlük hastane yatışlarının olduğu öğrenildi (%10).SonuçKlinik çalışmalar ışığında özellikle bizim çalışma dizayn ve popülasyonumuza en yakın parametrelere sahip CREST çalışması ışığında, kliniğimizde yapılan karotis arter stentleme işlemlerinin başarısını ölçmeye çalıştık. Çalışmaya alınan hastalara emboli koruma cihazlarını kullanmaya çalıştık. Takip dönemi sonucunda cerrahi açısından yüksek riskli hasta grubunda karotis arter stentlemenin iyi bir alternatif olabileceğini düşünüyoruz.

Kaynakça

  • Grau AJ, Weimar C, Buggle F, Heinrich A, Goertler M, Neumaier S, et al. Risk factors, outcome, and treatment in subtypes of ischemic stroke: the German stroke data bank. Stroke 2001;32:2559–2566.
  • ESC Guidelines on the diagnosis and treatment of peripheral artery diseases Document covering atherosclerotic disease of extracranial carotid and vertebral, mesenteric, renal, upper and lower extremity arteries The Task Force on the Diagnosis and Treatment of Peripheral Artery Diseases of the Europen Society of Cardiology (ESC).
  • Grant EG, Benson CB, Moneta GL, Alexandrov AV, Baker JD, Bluth EI, et al. Carotid artery stenosis: gray-scale and Doppler US diagnosis—Society of Radiologists in Ultrasound Consensus Conference. Radiology 2003;229:340–346.
  • Faxon DP, Fuster V, Libby P, Beckman LA, Hiatt WR, Thompson RW, et al. Atherosclerotic vascular disease conference: Writing Group III: pathophysiology. Circulation 2004:109:2617-25.
  • Eckard DA, Zarmov DM, McPherson CM, Siegel EL, Eckard VR, Batnitzky S, et al. Intracranial internal carotid artery angioplasty: technique with clinical and radiographic result and follow-up. AJR 1999;172:703-707.
  • Theron JG, Payelle GG, Coskun O, Huet HF, Guimaraens L. Carotid artery stenosis: treatment with protected balloon angioplasty and stent placement. Radiology 1996;201:627-636.
  • Interventional In: Henry M, Amor M, editors. 9th International course book on Peripheral Vascular Intervention. Europe Bd;1988.p.607-20.
  • 2011 ASA /ACCF /AHA /AANN /AANS /ACR /ASNR /CNS /SAIP /SCAI /SIR / SNIS/SVM/SVS Guideline on the Management of Patients With Extracranial Carotid and Vertebral Artery Disease.
  • Katzen BT, Ardid MI, MacLean AA, Kovacs MF, Zemel G, Benenati JF, et al. Bivalirudin as an anticoagulation agent: safety and efficacy in peripheral interventions. J Vasc Interv Radiol 2005;16:1183–7.
  • Schneider LM, Polena S, Roubin G, Iyer S, Vitek J, Panagopoulos G, et al. Carotid stenting and bivalirudin with and without vascular closure: 3-year analysis of procedural outcomes. Catheter Cardiovasc Interv 2010;75:420–6.
  • Osborn AG. Diagnostic Cerebral Angiography. 2 nd edition. Philadelphia: Lippincott, 1999.
  • Strong JP, Malcom GT, Mc Mahan CA, Tracy RE, Newman WP 3rd, Herderick EE, et al. Prevalence and extent of atherosclerosis in adolescents and young adults. Implication for prevention from the pathobiological determinants of atherosclerosis in youth study. JAMA 1999;281:727-35.
  • McGill HC Jr, McMahan CA, Zieske AW, Tracy RE, Malcom GT, Herderick EE, et al. Association of Coronary Heart Disease Risk Factors with microscopic qualities of coronary atherosclerosis in youth. Circulation 2000;102(4):374-9.
  • Sata M, Saiura A, Kunisato A, Tojo A, Okada S, Tokuhisa T, et al. Hematopoietic stem cells differentiate into vascular cells that participate in the pathogenesis of atherosclerosis. Nat Med 2002;8(4):403-9.
  • O'Brien KD, Olin KL, Alpers CE, Chiu W, Ferguson M, Hudkins K, et al. Comparison of apolipoprotein and proteoglycan deposits in human coronary atherosclerotic plaques: colocalization of biglycan with apolipoproteins. Circulation 1998;98(6):519-27.
  • Wardlaw JM, Chappell FM, Stevenson M, De Nigris E, Thomas S, Gillard J, et al. Accurate, practical and cost-effective assessment of carotid stenosis in the UK. Health Technol Assess 2006;10:iii– iv, ix–x, 1–182.
  • Economopoulos KP, Sergentanis TN, Tsivgoulis G, Mariolis AD, Stefanadis C. Carotid artery stenting versus carotid endarterectomy: a comprehensive meta-analysis of short-term and long-term outcomes. Stroke 2011;42:687–692.
Toplam 17 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Bölüm Makaleler
Yazarlar

Ahmet Göktuğ Ertem Bu kişi benim

Ramazan Akdemir Bu kişi benim

Harun Kılıç Bu kişi benim

Ekrem Yeter Bu kişi benim

Yayımlanma Tarihi 1 Haziran 2013
Gönderilme Tarihi 7 Eylül 2015
Yayımlandığı Sayı Yıl 2013

Kaynak Göster

AMA Ertem AG, Akdemir R, Kılıç H, Yeter E. Karotis artere stent yerleştirmenin orta dönem klinik sonuçları.: Tek merkez çalışması. Sakarya Tıp Dergisi. Haziran 2013;3(2):65-71. doi:10.5505/sakaryamj.2013.55265

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