Beyin Manyetik Rezonans Görüntüsünde Anatomik Atlas Oluşturma yöntemi ve Anatomi Eğitimine Katkısı

Abstract

Amaç: Manyetik rezonans (MR) görüntülerinde Beyin yapılarının 3D görsellerinde parselasyon yapılarak beyin atlası oluşturulması amaçlanmıştır. Bu amaçla oluşturulan Anatomi atlasının, hem Anatomi eğitimine hem de klinik çalışmalara katkı sunacağı hedeflenmiştir. Materyal ve Metod: Amaç: Manyetik rezonans görüntüleri üzerinde tam otomatik parselasyon yazılımı olan MriStudio kullanılmıştır. MriStudio beyin görüntülerinde tam otomatik segmentasyon olanağı sağlar. DTIStudio, DiffeoMap ve ROIEditor olmak üzere üç yazılımdan oluşmaktadır. MriStudio yazılımları kullanılarak istenilen beyin yapısı MASK (görüntüyü arka plandan ayrıştırarak etiketlerinin atanması) olarak kaydedilir. Beyinde bulunan 189 bölgeye ait ROI'leri elde etmek için, ROI atlas uygulanmıştır. Her bir beyin bölgesi görüntüsü MricroGL yazılımı ile her bir kesit seviyesinde ve üç boyutlu olarak kayıt edilmiştir. Bulgular: Beyin Manyetik rezonans görüntüleri üzerinde kullanılan üç yönteme (manuel, MriStudio ve Ibaspm) ait hacim değerleri elde edilmiştir. Manuel ölçümleri altın standart olarak kabul ederek MriStudio ile elde edilen değerlerin manuel ölçümlere daha yakın olduğu görülmüştür. Beyine ait 189 bölgenin hacmi ve kesit alanı elde edilmiştir (Tablo 1). Sonuç: Anatomik olarak normal bireylere ait Manyetik rezonans görüntüleri kullanılarak atlas elde etmek mümkündür. Oluşturulan bu tür bireysel atlaslarla beyin yapılarının hacim değerlerinin elde edilmesi de ikinci bir avantaj oluşturacaktır. Ayrıca beyin içindeki yapıların kesitsel ve 3 boyutlu gösterilerek beyin anatomisinin anlaşılmasında ve klinik problemlerde teşhise katkı sunmada yararlı olacağı kanaatindeyiz.

Keywords

• MriStudio
• IBASPM
• Beyin Parselasyonu
• Beyin 3D Atlas
• MRG

Anatomical Atlas Creation Method in Brain Magnetic Resonance Image and Its Contribution to Anatomy Education

Abstract

Objective: The aim was to create a brain atlas by creating 3D visualizations of the structures of the brain tissue in magnetic resonance images and parceling them. It is aimed that the anatomy atlas created for this purpose will contribute to both anatomy education and clinical studies. Materials and methods: Objective: MriStudio, a fully automatic segmentation software, was used on magnetic resonance images. MriStudio provides fully automatic segmentation of brain images. It consists of three software programs: DTIStudio, DiffeoMap and ROIEditor. Using MriStudio software, the desired brain structure is saved as MASK (separating the image from the background and assigning labels). ROI atlas was applied to obtain ROIs for 189 brain regions. Each brain region image was registered at each slice level and in three dimensions with MricroGL software. Results: The volume values of three methods (manual, MriStudio and Ibaspm) were obtained on brain magnetic resonance images. By accepting manual measurements as the gold standard, it was observed that the values obtained with MriStudio were closer to manual measurements. The volume and cross-sectional area of 189 regions of the brain were obtained (Table 1). Conclusion: It is possible to obtain atlases of anatomically normal individuals using magnetic resonance images. Obtaining the volume values of brain structures with such individual atlases will be a second advantage. In addition, we believe that it will be useful in understanding the brain anatomy and contributing to the diagnosis of clinical problems by showing the structures in the brain cross-sectionally and in 3D.

Keywords

• MriStudio
• IBASPM
• Brain Parcellation
• Brain 3D Atlas
• MRI

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