Araştırma Makalesi
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Antimicrobial Activity of Ethanol and Methanol Extracts of Suillus bovinus (L.) Roussel Mushroom Collected from Selçuk University Campus

Yıl 2024, , 60 - 65, 01.10.2024
https://doi.org/10.35238/sufefd.1522776

Öz

The aim of this study is to determine the antimicrobial activity of ethanol and methanol extracts of Suillus bovinus mushroom against some standard pathogenic microorganisms. Broth microdilution method was used to detect antimicrobial activity. It was determined that methanol and ethanol extract of S. bovinus showed activity against gram-positive Staphylococcus aureus and Sarcina lutea and gram-negative Salmonella enteritidis bacteria at a dose of 6.25 mg/ml. It was detected that both extracts had an antibacterial effect against gram-negative Pseudomonas aeruginosa at a dose of 3.12 mg/ml. It was determided that both extracts were ineffective against Escherichia coli and Klebsiella pneumoniae bacteria. The strain in which methanol and ethanol extracts showed the highest activity was the gram-positive Bacillus cereus strain, with MIC (Minimum Inhibition Concentration) values of 0.19 mg/ml and 0.78 mg/ml, respectively. Additionally, the study showed that neither extract had an antifungal effect against the Candida albicans yeast strain. As a result, it is thought that the S. bovinus fungus has antibacterial activity and that the antimicrobial compounds obtained from this species with further studies will be a potential source for the development of new drugs and therapeutic agents.

Kaynakça

  • Arif, T., Bhosale, J., Kumar, N., Mandal, T., Bendre, R., Lavekar, G. and Dabur, R., (2009), Natural products–antifungal agents derived from plants, Journal of Asian natural products research, 11 (7), 621-638.
  • Aslim, B. and Ozturk, S., (2011), Phenolic composition and antimicrobial and antioxidant activities of Leucoagaricus leucothites (Vittad.) Wasser, Journal of Medicinal Food, 14 (11), 1419-1424.
  • Aytar, E. C., Akata, İ. and Açık, L., (2020), Antioxidant, antimicrobial and anti-proliferative activity of Suillus luteus (L.) Roussel extracts, Journal Of Faculty Of Pharmacy Of Ankara University, 44 (3), 373-387.
  • Aytar, E. C. and Özmen, A., (2020), Cytotoxic and apoptotic activities of Rhizopogon roseolus (Corda) Th. Fr. extracts, International Journal of Secondary Metabolite, 7 (1), 54-62.
  • Chang, R., (1996), Functional properties of edible mushrooms, Nutrition Reviews, 54 (11), S91.
  • Chaudhary, P., Panth, N., Raut, B. K., Pokhrel, N., Shrestha, N., Shakya, S., Thapa, B., Mishra, A. D. and Parajuli, N., (2023), Biochemical, Antimicrobial, and Antioxidant activities of some wild Mushrooms from Nepal, Bıbechena, 20 (2), 161-174.
  • Cör Andrejč, D., Knez, Ž. and Knez Marevci, M., (2022), Antioxidant, antibacterial, antitumor, antifungal, antiviral, anti-inflammatory, and nevro-protective activity of Ganoderma lucidum: An overview, Frontiers in pharmacology, 13, 934982.
  • Engel, H., Dermek, A., Klofac, W., Ludwig, E. and Brückner, T., (1996), Schmier-und Filzröhrlinge sl in Europa, Engel, p. Gao, Y., Tang, W., Gao, H., Chan, E., Lan, J., Li, X. and Zhou, S., (2005), Antimicrobial activity of the medicinal mushroom Ganoderma, Food Reviews International, 21 (2), 211-229.
  • Gürgen, A., Bal, C., Krupodorova, T. and Sevindik, M., (2024), Anticholinesterase, Antimicrobial and Antioxidant Activities of Wild Mushroom Suillus bellinii (Inzenga) Kuntze, ISERDAR, 2 (1), 16-23.
  • Gyawali, R. and Ibrahim, S. A., (2014), Natural products as antimicrobial agents, Food control, 46, 412-429.
  • Han, E. H., Hwang, Y. P., Kim, H. G., Choi, J. H., Im, J. H., Yang, J. H., Lee, H.-U., Chun, S.-S., Chung, Y. C. and Jeong, H. G., (2011), Inhibitory effect of Pleurotus eryngii extracts on the activities of allergic mediators in antigen-stimulated mast cells, Food and chemical toxicology, 49 (6), 1416-1425.
  • Hatvani, N., (2001), Antibacterial effect of the culture fluid of Lentinus edodes mycelium grown in submerged liquid culture, International Journal of Antimicrobial Agents, 17 (1), 71-74.
  • Hirasawa, M., Shouji, N., Neta, T., Fukushima, K. and Takada, K., (1999), Three kinds of antibacterial substances from Lentinus edodes (Berk.) Sing.(Shiitake, an edible mushroom), International Journal of Antimicrobial Agents, 11 (2), 151-157.
  • Knudsen, H. and Vesterholt, J., (2008), Funga Nordica: agaricoid, boletoid and cyphelloid genera, (No Title). Lull, C., Wichers, H. J. and Savelkoul, H. F., (2005), Antiinflammatory and immunomodulating properties of fungal metabolites, Mediators of inflammation, 2005 (2), 63-80.
  • Matijašević, D., Pantić, M., Rašković, B., Pavlović, V., Duvnjak, D., Sknepnek, A. and Nikšić, M., (2016), The antibacterial activity of Coriolus versicolor methanol extract and its effect on ultrastructural changes of Staphylococcus aureus and Salmonella Enteritidis, Frontiers in Microbiology, 7, 1226.
  • Opletal, L., Jahodar, L., Chobot, V., Zdanský, P., Lukes, J., Bratova, M., Solichova, D., Blunden, G., Dacke, C. and Patel, A., (1997), Evidence for the anti-hyperlipidaemic activity of the edible fungus Pleurotus ostreatus, British journal of biomedical science, 54 (4), 240-243.
  • Parekh, J. and Chanda, S., (2007), In vitro screening of antibacterial activity of aqueous and alcoholic extracts of various Indian plant species against selected pathogens from Enterobacteriaceae, Afr J Microbiol Res, 1 (6), 92-99.
  • Reis, F. S., Stojković, D., Barros, L., Glamočlija, J., Ćirić, A., Soković, M., Martins, A., Vasconcelos, M. H., Morales, P. and Ferreira, I. C., (2014), Can Suillus granulatus (L.) Roussel be classified as a functional food?, Food & Function, 5 (11), 2861-2869.
  • Ren, L., Perera, C. and Hemar, Y., (2012), Antitumor activity of mushroom polysaccharides: a review, Food & Function, 3 (11), 1118-1130.
  • Sesli, E., Asan, A., Selçuk, F., Abacı Günyar, Ö., Akata, I., Akgül, H., Aktaş, S., Alkan, S., Allı, H. and Aydoğdu, H., (2020), Türkiye mantarları listesi, İstanbul: Ali Nihat Gökyiğit Vakfı Yayını.
  • Shamtsyan, M., Konusova, V., Maksimova, Y., Goloshchev, A., Panchenko, A., Simbirtsev, A., Petrishchev, N. and Denisova, N., (2004), Immunomodulating and anti-tumor action of extracts of several mushrooms, Journal of Biotechnology, 113 (1-3), 77-83.
  • Song, X., Ren, Z., Wang, X., Jia, L. and Zhang, C., (2020), Antioxidant, anti-inflammatory and renoprotective effects of acidic-hydrolytic polysaccharides by spent mushroom compost (Lentinula edodes) on LPS-induced kidney injury, International journal of biological macromolecules, 151, 1267-1276.
  • Statements, P., (2000), Mushrooms, civilization and history, Growing Gourmet and Medical Mushrooms, 1-4. Šutara, J., Janda, V. and Mikšík, M., (2009), Hřibovité houby: Čeled''Boletaceae'a rody'Gyrodon, 'Gyroporus', 'Boletinus'a'Suillus', Academia Praha, p.
  • Uysal, I., Koçer, O., Mohammed, F. S., Lekesiz, Ö., Doğan, M., Şabik, A. E., Sevindik, E., Gerçeker, F. Ö. and Sevindik, M., (2023), Pharmacological and nutritional properties: Genus Salvia, Advances in Pharmacology and Pharmacy, 11 (2), 140-155.
  • Volcão, L. M., Fernandes, C. L. F., Ribeiro, A. C., de Lima Brum, R., Eslabão, C. F., Badiale-Furlong, E., Ramos, D. F., Bernardi, E. and da Silva Júnior, F. M. R., (2021), Bioactive extracts of Russula xerampelina and Suillus granulatus in the in vitro control of Pseudomonas aeruginosa phytopathogenic, South African Journal of Botany, 140, 218-225.
  • Wasser, S. P. and Weis, A. L., (1999), Therapeutic effects of substances occurring in higher Basidiomycetes mushrooms: a modern perspective, Critical Reviews™ in Immunology, 19 (1).
  • Yamaç, M. and Bilgili, F., (2006), Antimicrobial activities of fruit bodies and/or mycelial cultures of some mushroom isolates, Pharmaceutical biology, 44 (9), 660-667.
  • Zengin, G., Uysal, A., Gunes, E. and Aktumsek, A., (2014), Survey of phytochemical composition and biological effects of three extracts from a wild plant (Cotoneaster nummularia Fisch. et Mey.): A potential source for functional food ingredients and drug formulations, PLoS One, 9 (11), e113527.
  • Živković, L., Bajić, V., Bruić, M., Borozan, S., Popić, K., Topalović, D., Santibanez, J. and Spremo-Potparević, B., (2019), Antigenotoxic and antioxidant potential of medicinal mushrooms (Immune Assist) against DNA damage induced by free radicals-an in vitro study, Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 845, 403078.

Selçuk Üniversitesi Kampüsünden Toplanan Suillus bovinus (L.) Roussel Mantarının Etanol ve Metanol Özütlerinin Antimikrobiyal Aktivitesi

Yıl 2024, , 60 - 65, 01.10.2024
https://doi.org/10.35238/sufefd.1522776

Öz

Bu çalışmanın amacı Suillus bovinus mantarının etanol ve metanol özütlerinin bazı standart patojen mikoorganizmalara karşı antimikrobiyal aktivitesini belirlemektir. Antimikrobiyal aktiviteyi saptamak için sıvı mikrodilüsyon metodu kullanılmıştır. S. bovinus'un metanol ve etanol özütünün, gram pozitif Staphylococcus aureus ve Sarcina lutea, gram negatif Salmonella enteritidis bakterilerine karşı 6.25 mg/ml dozda antibakteriyel aktivite gösterdiği tespit edilmiştir. Her iki özütün gram negatif Pseudomonas aeruginosa’ya ise 3.12 mg/ml dozunda antibakteriyal etki gösterdiği saptanmıştır. Escherichia coli ve Klebsiella pneumoniae bakterilerine karşı her iki özütün de etkisiz olduğu belirlenmiştir. Metanol ve etanol özütü sırasıyla 0.19 mg/ml ve 0.78 mg/ml MİK (Minimum İnhibisyon Konsantrasyonu) değeriyle en yüksek aktivite gösterdikleri suş ise gram pozitif Bacillu cereus suşu olmuştur. Ayrıca yapılan çalışmada Candida albicans maya suşuna karşı her iki özütün antifungal bir etki göstermediği görülmüştür. Sonuç olarak çalışmada, S. bovinus mantarının antibakteriyal aktiviteye sahip olduğu ve ileriki çalışmalarla bu türden elde edilen antimikrobiyal bileşiklerin, yeni ilaçların ve terapötik ajanların geliştirilmesi için potansiyel bir kaynak olacağı düşünülmektedir.

Etik Beyan

Bu çalışmanın hazırlanma sürecinde bilimsel ve etik ilkelere uyulduğu ve yararlanılan tüm çalışmaların kaynakçada belirtildiği beyan olunur

Teşekkür

Çalışmada kullanılan mantarın tür teşhisini yapan ve her türlü desteklerini sunan Dr. Öğr. Ü. Sinan ALKAN’a teşekkürlerimi sunarım.

Kaynakça

  • Arif, T., Bhosale, J., Kumar, N., Mandal, T., Bendre, R., Lavekar, G. and Dabur, R., (2009), Natural products–antifungal agents derived from plants, Journal of Asian natural products research, 11 (7), 621-638.
  • Aslim, B. and Ozturk, S., (2011), Phenolic composition and antimicrobial and antioxidant activities of Leucoagaricus leucothites (Vittad.) Wasser, Journal of Medicinal Food, 14 (11), 1419-1424.
  • Aytar, E. C., Akata, İ. and Açık, L., (2020), Antioxidant, antimicrobial and anti-proliferative activity of Suillus luteus (L.) Roussel extracts, Journal Of Faculty Of Pharmacy Of Ankara University, 44 (3), 373-387.
  • Aytar, E. C. and Özmen, A., (2020), Cytotoxic and apoptotic activities of Rhizopogon roseolus (Corda) Th. Fr. extracts, International Journal of Secondary Metabolite, 7 (1), 54-62.
  • Chang, R., (1996), Functional properties of edible mushrooms, Nutrition Reviews, 54 (11), S91.
  • Chaudhary, P., Panth, N., Raut, B. K., Pokhrel, N., Shrestha, N., Shakya, S., Thapa, B., Mishra, A. D. and Parajuli, N., (2023), Biochemical, Antimicrobial, and Antioxidant activities of some wild Mushrooms from Nepal, Bıbechena, 20 (2), 161-174.
  • Cör Andrejč, D., Knez, Ž. and Knez Marevci, M., (2022), Antioxidant, antibacterial, antitumor, antifungal, antiviral, anti-inflammatory, and nevro-protective activity of Ganoderma lucidum: An overview, Frontiers in pharmacology, 13, 934982.
  • Engel, H., Dermek, A., Klofac, W., Ludwig, E. and Brückner, T., (1996), Schmier-und Filzröhrlinge sl in Europa, Engel, p. Gao, Y., Tang, W., Gao, H., Chan, E., Lan, J., Li, X. and Zhou, S., (2005), Antimicrobial activity of the medicinal mushroom Ganoderma, Food Reviews International, 21 (2), 211-229.
  • Gürgen, A., Bal, C., Krupodorova, T. and Sevindik, M., (2024), Anticholinesterase, Antimicrobial and Antioxidant Activities of Wild Mushroom Suillus bellinii (Inzenga) Kuntze, ISERDAR, 2 (1), 16-23.
  • Gyawali, R. and Ibrahim, S. A., (2014), Natural products as antimicrobial agents, Food control, 46, 412-429.
  • Han, E. H., Hwang, Y. P., Kim, H. G., Choi, J. H., Im, J. H., Yang, J. H., Lee, H.-U., Chun, S.-S., Chung, Y. C. and Jeong, H. G., (2011), Inhibitory effect of Pleurotus eryngii extracts on the activities of allergic mediators in antigen-stimulated mast cells, Food and chemical toxicology, 49 (6), 1416-1425.
  • Hatvani, N., (2001), Antibacterial effect of the culture fluid of Lentinus edodes mycelium grown in submerged liquid culture, International Journal of Antimicrobial Agents, 17 (1), 71-74.
  • Hirasawa, M., Shouji, N., Neta, T., Fukushima, K. and Takada, K., (1999), Three kinds of antibacterial substances from Lentinus edodes (Berk.) Sing.(Shiitake, an edible mushroom), International Journal of Antimicrobial Agents, 11 (2), 151-157.
  • Knudsen, H. and Vesterholt, J., (2008), Funga Nordica: agaricoid, boletoid and cyphelloid genera, (No Title). Lull, C., Wichers, H. J. and Savelkoul, H. F., (2005), Antiinflammatory and immunomodulating properties of fungal metabolites, Mediators of inflammation, 2005 (2), 63-80.
  • Matijašević, D., Pantić, M., Rašković, B., Pavlović, V., Duvnjak, D., Sknepnek, A. and Nikšić, M., (2016), The antibacterial activity of Coriolus versicolor methanol extract and its effect on ultrastructural changes of Staphylococcus aureus and Salmonella Enteritidis, Frontiers in Microbiology, 7, 1226.
  • Opletal, L., Jahodar, L., Chobot, V., Zdanský, P., Lukes, J., Bratova, M., Solichova, D., Blunden, G., Dacke, C. and Patel, A., (1997), Evidence for the anti-hyperlipidaemic activity of the edible fungus Pleurotus ostreatus, British journal of biomedical science, 54 (4), 240-243.
  • Parekh, J. and Chanda, S., (2007), In vitro screening of antibacterial activity of aqueous and alcoholic extracts of various Indian plant species against selected pathogens from Enterobacteriaceae, Afr J Microbiol Res, 1 (6), 92-99.
  • Reis, F. S., Stojković, D., Barros, L., Glamočlija, J., Ćirić, A., Soković, M., Martins, A., Vasconcelos, M. H., Morales, P. and Ferreira, I. C., (2014), Can Suillus granulatus (L.) Roussel be classified as a functional food?, Food & Function, 5 (11), 2861-2869.
  • Ren, L., Perera, C. and Hemar, Y., (2012), Antitumor activity of mushroom polysaccharides: a review, Food & Function, 3 (11), 1118-1130.
  • Sesli, E., Asan, A., Selçuk, F., Abacı Günyar, Ö., Akata, I., Akgül, H., Aktaş, S., Alkan, S., Allı, H. and Aydoğdu, H., (2020), Türkiye mantarları listesi, İstanbul: Ali Nihat Gökyiğit Vakfı Yayını.
  • Shamtsyan, M., Konusova, V., Maksimova, Y., Goloshchev, A., Panchenko, A., Simbirtsev, A., Petrishchev, N. and Denisova, N., (2004), Immunomodulating and anti-tumor action of extracts of several mushrooms, Journal of Biotechnology, 113 (1-3), 77-83.
  • Song, X., Ren, Z., Wang, X., Jia, L. and Zhang, C., (2020), Antioxidant, anti-inflammatory and renoprotective effects of acidic-hydrolytic polysaccharides by spent mushroom compost (Lentinula edodes) on LPS-induced kidney injury, International journal of biological macromolecules, 151, 1267-1276.
  • Statements, P., (2000), Mushrooms, civilization and history, Growing Gourmet and Medical Mushrooms, 1-4. Šutara, J., Janda, V. and Mikšík, M., (2009), Hřibovité houby: Čeled''Boletaceae'a rody'Gyrodon, 'Gyroporus', 'Boletinus'a'Suillus', Academia Praha, p.
  • Uysal, I., Koçer, O., Mohammed, F. S., Lekesiz, Ö., Doğan, M., Şabik, A. E., Sevindik, E., Gerçeker, F. Ö. and Sevindik, M., (2023), Pharmacological and nutritional properties: Genus Salvia, Advances in Pharmacology and Pharmacy, 11 (2), 140-155.
  • Volcão, L. M., Fernandes, C. L. F., Ribeiro, A. C., de Lima Brum, R., Eslabão, C. F., Badiale-Furlong, E., Ramos, D. F., Bernardi, E. and da Silva Júnior, F. M. R., (2021), Bioactive extracts of Russula xerampelina and Suillus granulatus in the in vitro control of Pseudomonas aeruginosa phytopathogenic, South African Journal of Botany, 140, 218-225.
  • Wasser, S. P. and Weis, A. L., (1999), Therapeutic effects of substances occurring in higher Basidiomycetes mushrooms: a modern perspective, Critical Reviews™ in Immunology, 19 (1).
  • Yamaç, M. and Bilgili, F., (2006), Antimicrobial activities of fruit bodies and/or mycelial cultures of some mushroom isolates, Pharmaceutical biology, 44 (9), 660-667.
  • Zengin, G., Uysal, A., Gunes, E. and Aktumsek, A., (2014), Survey of phytochemical composition and biological effects of three extracts from a wild plant (Cotoneaster nummularia Fisch. et Mey.): A potential source for functional food ingredients and drug formulations, PLoS One, 9 (11), e113527.
  • Živković, L., Bajić, V., Bruić, M., Borozan, S., Popić, K., Topalović, D., Santibanez, J. and Spremo-Potparević, B., (2019), Antigenotoxic and antioxidant potential of medicinal mushrooms (Immune Assist) against DNA damage induced by free radicals-an in vitro study, Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 845, 403078.
Toplam 29 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Bakteriyoloji
Bölüm Araştırma Makaleleri
Yazarlar

Erdoğan Güneş 0000-0003-2833-5710

Erken Görünüm Tarihi 21 Eylül 2024
Yayımlanma Tarihi 1 Ekim 2024
Gönderilme Tarihi 26 Temmuz 2024
Kabul Tarihi 26 Ağustos 2024
Yayımlandığı Sayı Yıl 2024

Kaynak Göster

APA Güneş, E. (2024). Selçuk Üniversitesi Kampüsünden Toplanan Suillus bovinus (L.) Roussel Mantarının Etanol ve Metanol Özütlerinin Antimikrobiyal Aktivitesi. Selçuk Üniversitesi Fen Fakültesi Fen Dergisi, 50(2), 60-65. https://doi.org/10.35238/sufefd.1522776
AMA Güneş E. Selçuk Üniversitesi Kampüsünden Toplanan Suillus bovinus (L.) Roussel Mantarının Etanol ve Metanol Özütlerinin Antimikrobiyal Aktivitesi. sufefd. Ekim 2024;50(2):60-65. doi:10.35238/sufefd.1522776
Chicago Güneş, Erdoğan. “Selçuk Üniversitesi Kampüsünden Toplanan Suillus Bovinus (L.) Roussel Mantarının Etanol Ve Metanol Özütlerinin Antimikrobiyal Aktivitesi”. Selçuk Üniversitesi Fen Fakültesi Fen Dergisi 50, sy. 2 (Ekim 2024): 60-65. https://doi.org/10.35238/sufefd.1522776.
EndNote Güneş E (01 Ekim 2024) Selçuk Üniversitesi Kampüsünden Toplanan Suillus bovinus (L.) Roussel Mantarının Etanol ve Metanol Özütlerinin Antimikrobiyal Aktivitesi. Selçuk Üniversitesi Fen Fakültesi Fen Dergisi 50 2 60–65.
IEEE E. Güneş, “Selçuk Üniversitesi Kampüsünden Toplanan Suillus bovinus (L.) Roussel Mantarının Etanol ve Metanol Özütlerinin Antimikrobiyal Aktivitesi”, sufefd, c. 50, sy. 2, ss. 60–65, 2024, doi: 10.35238/sufefd.1522776.
ISNAD Güneş, Erdoğan. “Selçuk Üniversitesi Kampüsünden Toplanan Suillus Bovinus (L.) Roussel Mantarının Etanol Ve Metanol Özütlerinin Antimikrobiyal Aktivitesi”. Selçuk Üniversitesi Fen Fakültesi Fen Dergisi 50/2 (Ekim 2024), 60-65. https://doi.org/10.35238/sufefd.1522776.
JAMA Güneş E. Selçuk Üniversitesi Kampüsünden Toplanan Suillus bovinus (L.) Roussel Mantarının Etanol ve Metanol Özütlerinin Antimikrobiyal Aktivitesi. sufefd. 2024;50:60–65.
MLA Güneş, Erdoğan. “Selçuk Üniversitesi Kampüsünden Toplanan Suillus Bovinus (L.) Roussel Mantarının Etanol Ve Metanol Özütlerinin Antimikrobiyal Aktivitesi”. Selçuk Üniversitesi Fen Fakültesi Fen Dergisi, c. 50, sy. 2, 2024, ss. 60-65, doi:10.35238/sufefd.1522776.
Vancouver Güneş E. Selçuk Üniversitesi Kampüsünden Toplanan Suillus bovinus (L.) Roussel Mantarının Etanol ve Metanol Özütlerinin Antimikrobiyal Aktivitesi. sufefd. 2024;50(2):60-5.

Dergi Sahibi: Selçuk Üniversitesi Fen Fakültesi Adına Rektör Prof. Dr. Hüseyin YILMAZ
Selçuk Üniversitesi Fen Fakültesi Fen Dergisi temel bilimlerde ve diğer uygulamalı bilimlerde özgün sonuçları olan Türkçe ve İngilizce makaleleri kabul eder. Dergide ayrıca güncel yenilikleri içeren derlemelere de yer verilebilir.
Selçuk Üniversitesi Fen Fakültesi Fen Dergisi;
İlk olarak 1981 yılında S.Ü. Fen-Edebiyat Fakültesi Dergisi olarak yayın hayatına başlamış; 1984 yılına kadar (Sayı 1-4) bu adla yayınlanmıştır.
1984 yılında S.Ü. Fen-Edeb. Fak. Fen Dergisi olarak adı değiştirilmiş 5. sayıdan itibaren bu isimle yayınlanmıştır.
3 Aralık 2008 tarih ve 27073 sayılı Resmi Gazetede yayımlanan 2008/4344 sayılı Bakanlar Kurulu Kararı ile Fen-Edebiyat Fakültesi; Fen Fakültesi ve Edebiyat Fakültesi olarak ayrılınca 2009 yılından itibaren dergi Fen Fakültesi Fen Dergisi olarak çıkmıştır.
2016 yılından itibaren DergiPark’ta taranmaktadır.


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